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2006 19
2007 35
2008 44
2009 54
2010 50
2011 53
2012 72
2013 97
2014 93
2015 94
2016 119
2017 118
2018 125
2019 127
2020 154
2021 162
2022 149
2023 115
2024 54

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[Analysis of risk factors for long-term overactive bladder after radical prostatectomy].
Yan Y, Li X, Xia H, Zhu X, Zhang Y, Zhang F, Liu K, Liu C, Ma L. Yan Y, et al. Beijing Da Xue Xue Bao Yi Xue Ban. 2024 Aug 18;56(4):589-593. Beijing Da Xue Xue Bao Yi Xue Ban. 2024. PMID: 39041550 Free article. Chinese.
Clinical baseline information, comprehensive imaging features, perioperative parameters, preoperative urinary control status, pathological diagnosis, and the incidence of OAB within one year postoperatively were collected and analyzed. ...
Clinical baseline information, comprehensive imaging features, perioperative parameters, preoperative urinary control status, patholo …
Clinical efficacy and safety analysis of type A botulinum toxin in the treatment of adolescents with refractory overactive bladder.
Li J, Liu W, Tang C, Pan H, Song C. Li J, et al. Medicine (Baltimore). 2024 Jul 5;103(27):e38803. doi: 10.1097/MD.0000000000038803. Medicine (Baltimore). 2024. PMID: 38968476 Free PMC article.
After the first treatment, 5 patients had mild hematuria, 4 patients had urinary tract infection, and 1 patient had urinary retention, which was relieved after catheterization. ...In adolescents with refractory overactive bladder who do not respond well to co …
After the first treatment, 5 patients had mild hematuria, 4 patients had urinary tract infection, and 1 patient had urinary
The impact of bladder problems on well-being in multiple sclerosis - A cross-sectional study.
Islamoska S, Forman CR, Panicker JN, Flachenecker P, Phé V, Brichetto G, Blok B, Barken KB. Islamoska S, et al. Mult Scler Relat Disord. 2024 Jul;87:105661. doi: 10.1016/j.msard.2024.105661. Epub 2024 May 3. Mult Scler Relat Disord. 2024. PMID: 38728957 Free article.
Among pwMS, 55 % reported bladder problems indicating overactive bladder (OAB), and 40 % reported self-experienced urinary retention. Self-management of bladder problems was reported by 32 %, 33 % were yet to have problem resolution, and 45 % reported a wish to receive bla …
Among pwMS, 55 % reported bladder problems indicating overactive bladder (OAB), and 40 % reported self-experienced urinary retention. …
The association between wet overactive bladder and consumption of tea, coffee, and caffeine: Results from 2005-2018 National Health and Nutrition Examination Survey.
Tang F, Zhang J, Huang R, Zhou H, Yan T, Tang Z, Li Z, Lu Z, Huang S, He Z. Tang F, et al. Clin Nutr. 2024 Jun;43(6):1261-1269. doi: 10.1016/j.clnu.2024.03.027. Epub 2024 Apr 16. Clin Nutr. 2024. PMID: 38653009 Free article.
The outcome was the risk of wet OAB that was diagnosed when the OAB symptom score was 3 with urgent urinary incontinence and excluded other diseases affecting diagnosis. ...
The outcome was the risk of wet OAB that was diagnosed when the OAB symptom score was 3 with urgent urinary incontinence and excluded …
Predicting muscarinic receptor occupancy in human bladder mucosa from urinary concentrations of antimuscarinic agents for overactive bladder.
Shiho M, Akashita G, Nakatani E, Tanaka S, Yamada S, Okura T. Shiho M, et al. Drug Metab Pharmacokinet. 2024 Jun;56:100998. doi: 10.1016/j.dmpk.2024.100998. Epub 2024 Jan 15. Drug Metab Pharmacokinet. 2024. PMID: 38583388 Free article.
To assess the pharmacologically relevant and selective muscarinic receptor occupancy in the bladder mucosa, we considered not only plasma drug concentrations but also urinary drug concentrations. The purpose of this study was to predict muscarinic receptor occupancy in the …
To assess the pharmacologically relevant and selective muscarinic receptor occupancy in the bladder mucosa, we considered not only plasma dr …
Preliminary analysis of stimulation parameters for sacral neuromodulation in different indications: a multicenter retrospective cohort study from China.
Meng L, Yan Z, Wang X, Zhang Y, Zhu Z, Zhu W, Ling Q, Sun X, Gu Y, Lv J, Li Y. Meng L, et al. Int J Surg. 2024 Jun 1;110(6):3536-3542. doi: 10.1097/JS9.0000000000001302. Int J Surg. 2024. PMID: 38445489 Free PMC article.
BACKGROUND: Sacral neuromodulation (SNM) is an effective approach for treating lower urinary tract dysfunction (LUTD), and stimulation programming is essential for successful treatment. ...RESULTS: After screening, 282 patients were enrolled and categorized into fou …
BACKGROUND: Sacral neuromodulation (SNM) is an effective approach for treating lower urinary tract dysfunction (LUTD), and sti …
The association between overactive bladder and systemic immunity-inflammation index: a cross-sectional study of NHANES 2005 to 2018.
Wei B, Zhao Y, Lin P, Qiu W, Wang S, Gu C, Deng L, Deng T, Li S. Wei B, et al. Sci Rep. 2024 May 31;14(1):12579. doi: 10.1038/s41598-024-63448-3. Sci Rep. 2024. PMID: 38822015 Free PMC article.
SII, calculated as platelet count neutrophil count/lymphocyte count, was categorized into quartiles. OAB was defined by the presence of urge urinary incontinence and nocturia. Weighted logistic regression models were used to examine the independent relationship between SII …
SII, calculated as platelet count neutrophil count/lymphocyte count, was categorized into quartiles. OAB was defined by the presence of urge …
Role of urine glycosaminoglycan levels in the diagnosis and follow-up in men with lower urinary tract symptoms.
Aydin HR, Sekerci CA, Kocakgol H, Basok BI, Bedir F, Guctas AO, Akdeniz F, Aksoy HZ, Ramazanoglu MA, Tanidir Y. Aydin HR, et al. Arch Ital Urol Androl. 2024 May 9;96(2):12367. doi: 10.4081/aiua.2024.12367. Arch Ital Urol Androl. 2024. PMID: 38722147 Free article.
OBJECTIVE: The aim of this study was to investigate whether urinary glycosaminoglycans (GAG) levels reflect clinical status in men with lower urinary tract symptoms and if they could be used as a marker in management of overactive bladder (OAB). ...CONCLUSION …
OBJECTIVE: The aim of this study was to investigate whether urinary glycosaminoglycans (GAG) levels reflect clinical status in men wi …
Intradetrusor Versus Suburothelial Onabotulinum Toxin A in Adults with Neurogenic and Non-neurogenic Overactive Bladder Syndrome: A Meta-Analysis.
Alshammari D, Yadav P, Ahmad I, Chancy M, Kim JK, Lorenzo A, Dos Santos J, Rickard M, Cunningham J, Chua ME. Alshammari D, et al. Arch Esp Urol. 2024 May;77(4):368-377. doi: 10.56434/j.arch.esp.urol.20247704.50. Arch Esp Urol. 2024. PMID: 38840279 Free article.
No significant difference was noted for mean compliance, mean bladder capacity, and mean maximum detrusor pressure. Urinary tract infections (UTIs) (p = 0.24) and acute urinary retention (p = 0.92) showed no significant difference between the two groups. ...
No significant difference was noted for mean compliance, mean bladder capacity, and mean maximum detrusor pressure. Urinary tract
Intravesical Injection of OnabotulinumtoxinA (Botulinum Toxin Type A) in Japanese Patients With Refractory Overactive Bladder.
Gotoh D, Torimoto K, Takamatsu N, Onishi K, Morizawa Y, Hori S, Nakai Y, Miyake M, Fujimoto K. Gotoh D, et al. In Vivo. 2024 May-Jun;38(3):1332-1337. doi: 10.21873/invivo.13573. In Vivo. 2024. PMID: 38688605 Free PMC article.
BACKGROUND/AIM: Botulinum toxin intravesical injection therapy (hereafter, botulinum therapy) is approved in Japan for treating urinary urgency, frequency, and urinary incontinence due to refractory overactive bladder or neurogenic bladder. Although botulinum therap …
BACKGROUND/AIM: Botulinum toxin intravesical injection therapy (hereafter, botulinum therapy) is approved in Japan for treating urinary
Diabetes mellitus, systemic inflammation and overactive bladder.
He Q, Wu L, Deng C, He J, Wen J, Wei C, You Z. He Q, et al. Front Endocrinol (Lausanne). 2024 Apr 29;15:1386639. doi: 10.3389/fendo.2024.1386639. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 38745959 Free PMC article.
Effect of Electroacupuncture Combined with Pelvic Floor Muscle Exercise on Urinary Symptoms, Sexual Dysfunction and Pelvic Floor Muscle Strength in Female Patients with Overactive Bladder: A Retrospective Study.
Yin Y, Zhao C, Liu M, Chen J. Yin Y, et al. Arch Esp Urol. 2024 Apr;77(3):256-262. doi: 10.56434/j.arch.esp.urol.20247703.34. Arch Esp Urol. 2024. PMID: 38715166 Free article.
CONCLUSIONS: The effect of electroacupuncture stimulation combined with pelvic floor muscle exercise is more significant, which can alleviate urinary symptoms, reduce urine leakage, enhance pelvic floor muscle strength and alleviate sexual dysfunction....
CONCLUSIONS: The effect of electroacupuncture stimulation combined with pelvic floor muscle exercise is more significant, which can alleviat …
Treatment Patterns with Mirabegron and Antimuscarinics for Overactive Bladder: A Prospective, Registry Study in Taiwan and South Korea (FAITH).
Oh SJ, Cho ST, Kuo HC, Chou EC, Hsu YC, Lee KS, Hadi F, Song Y, Sumarsono B. Oh SJ, et al. Adv Ther. 2024 Apr;41(4):1652-1671. doi: 10.1007/s12325-024-02784-2. Epub 2024 Mar 2. Adv Ther. 2024. PMID: 38430402 Free PMC article.
In multivariable models, baseline OABSS was the only variable significantly associated with change from baseline in OABSS, and patients with mild and moderate OAB had significantly better persistence with mirabegron than those with severe OAB. Urinary tract infectio …
In multivariable models, baseline OABSS was the only variable significantly associated with change from baseline in OABSS, and patients with …
Sacral Neuromodulation: Device Improvement and Current Applications in Urology.
Spilotros M, Gerbasi S, Lasorsa F, de Rienzo G, Balducci L, Ditonno P, Lucarelli G. Spilotros M, et al. Medicina (Kaunas). 2024 Mar 20;60(3):509. doi: 10.3390/medicina60030509. Medicina (Kaunas). 2024. PMID: 38541235 Free PMC article. Review.
Sacral neuromodulation (SNM) offers a therapeutic approach to urological patients suffering from idiopathic overactive bladder (OAB) syndrome, with or without incontinence and non-obstructive urinary retention (NOR), who are not responding to or are not compliant with cons …
Sacral neuromodulation (SNM) offers a therapeutic approach to urological patients suffering from idiopathic overactive bladder (OAB) syndrom …
Primary care providers practice patterns regarding female pelvic floor disorders.
Weimer A, Hallock JL, Chen CCG. Weimer A, et al. Fam Med Community Health. 2024 Mar 14;12(1):e002448. doi: 10.1136/fmch-2023-002448. Fam Med Community Health. 2024. PMID: 38485284 Free PMC article.
RESULTS: Of the 153 respondents to the survey, more felt comfortable managing stress urinary incontinence (SUI) and overactive bladder (OAB), compared with pelvic organ prolapse (POP) and faecal incontinence (FI) and were less likely to refer patients with urinary s …
RESULTS: Of the 153 respondents to the survey, more felt comfortable managing stress urinary incontinence (SUI) and overactive bladde …
Real-Life Treatment Outcome of Botulinum Toxin A Injection on Overactive Bladder and Voiding Dysfunction in Patients with Central Nervous System Lesions.
Jiang YH, Jhang JF, Chen SF, Kuo HC. Jiang YH, et al. Toxins (Basel). 2024 Mar 1;16(3):123. doi: 10.3390/toxins16030123. Toxins (Basel). 2024. PMID: 38535789 Free PMC article.
PURPOSE: Neurogenic lower urinary tract dysfunction (NLUTD) is common in patients with neurological lesions in the central nervous system (CNS). ...RESULTS: The study included 74 patients receiving detrusor injections for OAB (36 with cerebrovascular accidents, 13 w …
PURPOSE: Neurogenic lower urinary tract dysfunction (NLUTD) is common in patients with neurological lesions in the central ner …
Sensing in Sacral Neuromodulation: A Feasibility Study in Subjects With Urinary Incontinence and Retention.
Goudelocke C, Jungbauer Nikolas LM, Bittner KC, Offutt SJ, Miller AE, Slopsema JP. Goudelocke C, et al. Neuromodulation. 2024 Feb;27(2):392-398. doi: 10.1016/j.neurom.2023.07.002. Epub 2023 Aug 16. Neuromodulation. 2024. PMID: 37589643 Free article.
The system collected SER recordings across a range of prespecified stimulation settings (electrode configuration combinations for bipolar stimulation and bipolar sensing) during intraoperative and postoperative sessions in 21 subjects with overactive bladder (OAB) and nonobstruct …
The system collected SER recordings across a range of prespecified stimulation settings (electrode configuration combinations for bipolar st …
Machine Learning-Based Classification of Transcriptome Signatures of Non-Ulcerative Bladder Pain Syndrome.
Akshay A, Besic M, Kuhn A, Burkhard FC, Bigger-Allen A, Adam RM, Monastyrskaya K, Hashemi Gheinani A. Akshay A, et al. Int J Mol Sci. 2024 Jan 26;25(3):1568. doi: 10.3390/ijms25031568. Int J Mol Sci. 2024. PMID: 38338847 Free PMC article.
Lower urinary tract dysfunction (LUTD) presents a global health challenge with symptoms impacting a substantial percentage of the population. ...
Lower urinary tract dysfunction (LUTD) presents a global health challenge with symptoms impacting a substantial percentage of …
Evaluating noninvasive brain stimulation to treat overactive bladder in individuals with multiple sclerosis: a randomized controlled trial protocol.
Salazar BH, Hoffman KA, Lincoln JA, Karmonik C, Rajab H, Helekar SA, Khavari R. Salazar BH, et al. BMC Urol. 2024 Jan 25;24(1):20. doi: 10.1186/s12894-023-01358-8. BMC Urol. 2024. PMID: 38273296 Free PMC article.
It can be accompanied by a myriad of pathologies and adverse effects such as neurogenic lower urinary tract dysfunction (NLUTD). Current treatment modalities for resolving NLUTD focus mainly on alleviating symptoms while the source of the discomfort emanates from a …
It can be accompanied by a myriad of pathologies and adverse effects such as neurogenic lower urinary tract dysfunction (NLUTD …
Radiofrequency as the New Opportunity in Treating Overactive Bladder and Urge Urinary Incontinence-A Single-Arm Pilot Study.
Franić D, Franić Ivanišević M, Verdenik I. Franić D, et al. Medicina (Kaunas). 2024 Jan 24;60(2):197. doi: 10.3390/medicina60020197. Medicina (Kaunas). 2024. PMID: 38399486 Free PMC article. Clinical Trial.
Background and Objectives: Until now, overactive bladder (OAB) with or without urge urinary incontinence (UUI) has been treated mainly in two ways: with behavioral methods and patient education, or using antimuscarinic drugs and/or beta-3 adrenergic receptor agonists. ...
Background and Objectives: Until now, overactive bladder (OAB) with or without urge urinary incontinence (UUI) has been treated mainl …
Seminal papers in urology: two-year outcomes of Sacral Neuromodulation Versus OnabotulinumtoxinA for refractory urgency urinary incontinence: a Randomized Trial.
Abd Wahab HHB, O'Callaghan M. Abd Wahab HHB, et al. BMC Urol. 2024 Jan 16;24(1):16. doi: 10.1186/s12894-023-01385-5. BMC Urol. 2024. PMID: 38229041 Free PMC article. Review.
In this critical review, we explore the study design, strengths and limitations of the paper: "Two-Year Outcomes of Sacral Neuromodulation Versus OnabotulinumtoxinA for Refractory Urgency Urinary Incontinence: A Randomized Trial." The paper reports 24 month follow-up data …
In this critical review, we explore the study design, strengths and limitations of the paper: "Two-Year Outcomes of Sacral Neuromodulation V …
Is bladder outlet obstruction rat model to induce overactive bladder (OAB) has similarity to human OAB? Research on the events in smooth muscle, collagen, interstitial cell and telocyte distribution.
Wishahi M, Hassan S, Kamal N, Badawy M, Hafiz E. Wishahi M, et al. BMC Res Notes. 2024 Jan 11;17(1):22. doi: 10.1186/s13104-023-06681-9. BMC Res Notes. 2024. PMID: 38212840 Free PMC article. Clinical Trial.
The Effect of induction of BOO was evaluated after 6 and 8 weeks. The rats were anesthetized, and the urinary bladder was removed, while the rat was unconscious under anaesthesia it was transferred to the inhalation anaesthesia cage for euthanasia, rats were sacrificed und …
The Effect of induction of BOO was evaluated after 6 and 8 weeks. The rats were anesthetized, and the urinary bladder was removed, wh …
Comparison of the efficacy and safety of onabotulinum toxin A and mirabegron for overactive bladder in elderly patients.
Karakeci A, Keles A, Onur R. Karakeci A, et al. Eur Rev Med Pharmacol Sci. 2024 Jan;28(1):350-356. doi: 10.26355/eurrev_202401_34923. Eur Rev Med Pharmacol Sci. 2024. PMID: 38235886 Free article.
Furthermore, 30 patients receiving 50 mg of mirabegron daily were compared. Micturition frequency, urgency of urinary incontinence, pad usage, and nocturia were all evaluated for efficacy. ...There was no significant difference in nocturia or maximum urine flow rate betwee …
Furthermore, 30 patients receiving 50 mg of mirabegron daily were compared. Micturition frequency, urgency of urinary incontinence, p …
Associations between Urinary Concentrations of Polycyclic Aromatic Hydrocarbons and Overactive Bladder in US Adults: Data from the National Health and Nutrition Examination Survey 2005-2016.
Pu S, Li Q, Tao Z, Wang S, Meng X, Wang S, Wang Z. Pu S, et al. Urol Int. 2024;108(2):137-145. doi: 10.1159/000536253. Epub 2024 Jan 12. Urol Int. 2024. PMID: 38219726 Free PMC article.
This study investigated the associations between urinary PAHs and OAB. METHODS: 7,146 adults aged over 20 who participated in the US National Health and Nutrition Examination Survey 2005-2016 were studied. ...RESULTS: There is a significant positive correlation between …
This study investigated the associations between urinary PAHs and OAB. METHODS: 7,146 adults aged over 20 who participated in the US …
Characterization and treatment of enuresis in overactive bladder patients.
Capdevila Vilaró B, Casal-Beloy I, Villalón Ferrero FN, Martín-Solé O, Coronas Soucheiron M, González-Temprano N, Larreina De la Fuente L, Carbonell Pradas M, Pérez-Bertólez S, Tarrado Castellarnau X, García-Aparicio L. Capdevila Vilaró B, et al. Cir Pediatr. 2024 Jan 1;37(1):27-32. doi: 10.54847/cp.2024.01.14. Cir Pediatr. 2024. PMID: 38180099 Free article. English, Spanish.
Variables achieved from the voiding calendar and PLUTSS (Pediatric Lower Urinary Tract Score System), as well as enuresis-related variables, were collected. ...
Variables achieved from the voiding calendar and PLUTSS (Pediatric Lower Urinary Tract Score System), as well as enuresis-rela …
A Multicenter Study Evaluating the FREquency of Use and Efficacy of a Novel Closed-Loop Wearable Tibial Neuromodulation System for Overactive Bladder and Urgency Urinary Incontinence (FREEOAB).
Goudelocke C, Sobol J, Poulos D, Enemchukwu E, Zaslau S, Dhir R. Goudelocke C, et al. Urology. 2024 Jan;183:63-69. doi: 10.1016/j.urology.2023.10.007. Epub 2023 Nov 7. Urology. 2024. PMID: 37944596 Free article.
Subjects used the transcutaneous tibial neuromodulation system, either once or three times weekly, with evaluations at weeks 1, 4, 8, and 12. Enrolled subjects (N = 96) were assessed for changes in urinary frequency, urgency, and urgency urinary incontinence episode …
Subjects used the transcutaneous tibial neuromodulation system, either once or three times weekly, with evaluations at weeks 1, 4, 8, and 12 …
Real-World Evidence for Risk Factors of Bruises and Fractures from Falls in Patients with Overactive Bladder: A Medical Record Analysis.
Miyajima S, Omaru T, Ishii T, Arima H, Shibata Y, Izaki T, Haga N. Miyajima S, et al. Int J Clin Pract. 2023 Dec 27;2023:3701823. doi: 10.1155/2023/3701823. eCollection 2023. Int J Clin Pract. 2023. PMID: 38179145 Free PMC article.
METHODS: We evaluated 1136 patients with OAB and aged 50 years who visited our hospital. Age, sex, frequency of nocturnal urination, and urinary incontinence type were investigated in the 360 eligible patients. ...
METHODS: We evaluated 1136 patients with OAB and aged 50 years who visited our hospital. Age, sex, frequency of nocturnal urination, and …
How I Do It: Transcutaneous tibial nerve stimulation TENSI+ system.
Cornu JN, Hashim H, Van Der Aa F, De Nunzio C, Perez VG, Ferreira R, Elterman DS. Cornu JN, et al. Can J Urol. 2023 Dec;30(6):11756-11761. Can J Urol. 2023. PMID: 38104335 Free article.
Recent studies have shown negligible differences between P-PTNS and T-PTNS efficacy in alleviating urinary urgency and frequency and QoL improvement and, overall no difference in efficacy over antimuscarinic regimens. ...Prospective multicentric data highlights TENSI+ to b …
Recent studies have shown negligible differences between P-PTNS and T-PTNS efficacy in alleviating urinary urgency and frequency and …
The endocrinology of the urinary bladder.
Bhattacharya S, Singal AK, Kalra S. Bhattacharya S, et al. J Pak Med Assoc. 2023 Dec;73(12):2488-2490. doi: 10.47391/JPMA.23-100. J Pak Med Assoc. 2023. PMID: 38083940 Free article. Review.
The urinary bladder primarily functions as a reservoir for urine. Apparently, it serves only a mechanical and passive role in the urinary tract, but closer scrutiny reveals that it has several meaningful endocrine interactions. ...
The urinary bladder primarily functions as a reservoir for urine. Apparently, it serves only a mechanical and passive role in the …
Impact of deep resection of endometriosis in the pelvis on urodynamic parameters.
Farias JC, Nascimento MDDSB, Leal PDC, Oliveira CMB, Moura ECR. Farias JC, et al. Acta Cir Bras. 2023 Dec 1;38:e386323. doi: 10.1590/acb386323. eCollection 2023. Acta Cir Bras. 2023. PMID: 38055398 Free PMC article.
METHODS: A prospective observational study conducted with female patients diagnosed with deep pelvic endometriosis before and after endometriosis resection surgery. Clinical history, image exams, the Female Lower Urinary Tract Symptoms questionnaire, urodynamic exam …
METHODS: A prospective observational study conducted with female patients diagnosed with deep pelvic endometriosis before and after endometr …
Importance of Regular Examination and Follow-up in Pediatric Patients with Neurogenic Bladder: 24-Month Follow-up Study Using a Japanese Health Insurance Database.
Izumi N, Kitta T, Mitsui T. Izumi N, et al. Adv Ther. 2023 Dec;40(12):5519-5535. doi: 10.1007/s12325-023-02692-x. Epub 2023 Oct 16. Adv Ther. 2023. PMID: 37843724 Free PMC article.
A multivariate analysis evaluating the potential risk factors for the development of urinary tract infection (UTI) was performed. The diagnosis of spina bifida, demographics, baseline comorbidities, and early use of clean intermittent catheterization (CIC) and/or ov …
A multivariate analysis evaluating the potential risk factors for the development of urinary tract infection (UTI) was perform …
Long-term beneficial effects of mirabegron in pediatric patients with therapy-refractory neurogenic lower urinary tract dysfunction.
van Veen FEE, Schotman M, 't Hoen LA, Blok BFM, Scheepe JR. van Veen FEE, et al. J Pediatr Urol. 2023 Dec;19(6):753.e1-753.e8. doi: 10.1016/j.jpurol.2023.08.015. Epub 2023 Aug 19. J Pediatr Urol. 2023. PMID: 37658014 Free article.
INTRODUCTION: Neurogenic lower urinary tract dysfunction (NLUTD) in children can cause renal failure and urinary incontinence if not treated sufficiently. ...Changes in video-urodynamic parameters, the need for other NLUTD therapy during follow-up, patient-re …
INTRODUCTION: Neurogenic lower urinary tract dysfunction (NLUTD) in children can cause renal failure and urinary incont …
The Persistency Index: a novel screening tool for identifying myofascial pelvic floor dysfunction in patients seeking care for lower urinary tract symptoms.
Ackerman AL, Torosis M, Jackson NJ, Caron AT, Kaufman MR, Lowder JL, Routh JC. Ackerman AL, et al. Am J Obstet Gynecol. 2023 Dec;229(6):667.e1-667.e11. doi: 10.1016/j.ajog.2023.08.017. Epub 2023 Aug 24. Am J Obstet Gynecol. 2023. PMID: 37633575 Free PMC article.
BACKGROUND: Patients with myofascial pelvic floor dysfunction often present with lower urinary tract symptoms, such as urinary frequency, urgency, and bladder pressure. Often confused with other lower urinary tract disorders, this constellation …
BACKGROUND: Patients with myofascial pelvic floor dysfunction often present with lower urinary tract symptoms, such as urin
Efficacy and Safety of Sacral Neuromodulation by Converting Constant Frequency Stimulation Into Variable Frequency Stimulation in Patients With Detrusor Overactivity and Impaired Contractility: A Single-Center Prospective Study.
Zhu W, Shan S, Zhang G, Zhang Q, Zhang J, Che Y, Wen J, Wang Q. Zhu W, et al. Neuromodulation. 2023 Dec;26(8):1836-1844. doi: 10.1016/j.neurom.2022.07.002. Epub 2022 Aug 14. Neuromodulation. 2023. PMID: 35977853 Free article.
OBJECTIVES: In patients with detrusor overactivity with impaired contractility (DOIC), it is difficult to relieve abnormal lower urinary tract symptoms during both storage and voiding using sacral neuromodulation (SNM) with constant frequency stimulation (CFS). ...
OBJECTIVES: In patients with detrusor overactivity with impaired contractility (DOIC), it is difficult to relieve abnormal lower urinary
Two-Staged Sacral Neuromodulation for the Treatment of Nonobstructive Urinary Retention: A Multicenter Study Assessing Predictors of Success.
Coolen RL, Groen J, Stillebroer AB, Scheepe JR, Witte LPW, Blok BFM. Coolen RL, et al. Neuromodulation. 2023 Dec;26(8):1823-1830. doi: 10.1016/j.neurom.2022.04.042. Epub 2022 Jun 9. Neuromodulation. 2023. PMID: 35690510 Free article.
OBJECTIVES: The aims of this study were to 1) determine the success rate of the tined lead test phase in patients with nonobstructive urinary retention (NOUR), 2) determine predictive factors of a successful test phase in patients with NOUR, and 3) determine long-term trea …
OBJECTIVES: The aims of this study were to 1) determine the success rate of the tined lead test phase in patients with nonobstructive uri
Dynamic analysis of the individual patterns of intakes, voids, and bladder sensations reported in bladder diaries collected in the LURN study.
Andreev VP, Helmuth ME, Smith AR, Zisman A, Cameron AP, DeLancey JOL, Bushman WA. Andreev VP, et al. PLoS One. 2023 Nov 20;18(11):e0284544. doi: 10.1371/journal.pone.0284544. eCollection 2023. PLoS One. 2023. PMID: 37983243 Free PMC article.
The goal of this study was to develop the novel analytical approach and to perform an in-depth dynamic analysis of individual bladder diaries to inform which behavioral modifications would best reduce lower urinary tract symptoms, such as frequency and urgency. Thre …
The goal of this study was to develop the novel analytical approach and to perform an in-depth dynamic analysis of individual bladder diarie …
Rezūm water vapor thermal therapy in patients with benign prostatic hyperplasia: Initial real-world data from Japan.
Obinata D, Mochida J, Uehara R, Osawa M, Hashimoto S, Nakahara K, Yoshizawa T, Yamaguchi K, Takahashi S. Obinata D, et al. Medicine (Baltimore). 2023 Nov 17;102(46):e36055. doi: 10.1097/MD.0000000000036055. Medicine (Baltimore). 2023. PMID: 37986385 Free PMC article.
The International Prostate Symptom Score (IPSS), Overactive Bladder Symptom Score, and Core Lower Urinary Tract Symptom Score (CLSS) were used to assess symptoms before the procedure, and at 1 and 3 months after it. Urinary function indicators such as single …
The International Prostate Symptom Score (IPSS), Overactive Bladder Symptom Score, and Core Lower Urinary Tract Symptom Score …
Flat Magnetic Stimulation for Urge Urinary Incontinence.
Barba M, Cola A, Rezzan G, Costa C, Re I, Volontè S, Terzoni S, Frigerio M, Maruccia S. Barba M, et al. Medicina (Kaunas). 2023 Nov 14;59(11):1999. doi: 10.3390/medicina59111999. Medicina (Kaunas). 2023. PMID: 38004048 Free PMC article.
Arnold (DEKA, Calenzano, Italy) in women suffering from OAB syndrome associated with urinary incontinence. Materials and Methods: This prospective study included patients with OAB, urge urinary incontinence, and no ongoing OAB treatments. ...This makes FMS a promisi …
Arnold (DEKA, Calenzano, Italy) in women suffering from OAB syndrome associated with urinary incontinence. Materials and Methods: Thi …
Associations between exposure to organophosphate esters and overactive bladder in U.S. adults: a cross-sectional study.
Lin W, Wang H, Wu Z, Zhang W, Lin ME. Lin W, et al. Front Public Health. 2023 Nov 9;11:1186848. doi: 10.3389/fpubh.2023.1186848. eCollection 2023. Front Public Health. 2023. PMID: 38026372 Free PMC article.
Four urinary metabolites of organophosphate esters: diphenyl phosphate (DPHP), bis (1,3-dichloro-2-propyl) phosphate (BDCPP), bis (2-chloroethyl) phosphate (BCEP), and dibutyl phosphate (DBUP) were included in the study. Multivariate logistic regression and restricted cubi …
Four urinary metabolites of organophosphate esters: diphenyl phosphate (DPHP), bis (1,3-dichloro-2-propyl) phosphate (BDCPP), bis (2- …
Urinary beta 3-adrenoceptor as a diagnostic biomarker for overactive bladder in women.
Liang CC, Hsieh WC, Lo TS, Huang TX, Chou YC, Huang JY, Huang YH. Liang CC, et al. Sci Rep. 2023 Nov 8;13(1):19368. doi: 10.1038/s41598-023-46786-6. Sci Rep. 2023. PMID: 37938600 Free PMC article.
All OAB-related questionnaires and GRAS indicated improved posttreatment urinary health. After mirabegron treatment, the frequency of micturition and urgency episodes decreased, but the urinary beta 3-adrenoceptor/creatinine (Cr) ratio increased. The urinary
All OAB-related questionnaires and GRAS indicated improved posttreatment urinary health. After mirabegron treatment, the frequency of …
Progress in overactive bladder: novel avenues from psychology to clinical opinions.
Jin Z, Zhang Q, Yu Y, Zhang R, Ding G, Li T, Song Y. Jin Z, et al. PeerJ. 2023 Nov 1;11:e16112. doi: 10.7717/peerj.16112. eCollection 2023. PeerJ. 2023. PMID: 37927797 Free PMC article.
THE INTENDED AUDIENCE: Urological surgeon and psychologists majoring in urinary diseases. IMPLICATION: As a result of this information, we are able to develop a better understanding of the role of psychological factors in the development of OAB and suggest potential therap …
THE INTENDED AUDIENCE: Urological surgeon and psychologists majoring in urinary diseases. IMPLICATION: As a result of this informatio …
Predicting Mirabegron Treatment Response in Patients with Overactive Bladder: A Post Hoc Analysis of Data from Clinical Trials.
Matta R, Saskin R, Neu S, Locke JA, Kowalczyk A, Steup A, Herschorn S. Matta R, et al. Eur Urol Focus. 2023 Nov;9(6):957-965. doi: 10.1016/j.euf.2023.04.001. Epub 2023 Apr 27. Eur Urol Focus. 2023. PMID: 37120417 Free article.
Mirabegron treatment was associated with a lower number of urinations and occurrences of urinary incontinence per day. Factors associated with worse responses to the medication included being obese....
Mirabegron treatment was associated with a lower number of urinations and occurrences of urinary incontinence per day. Factors associ …
The Assessment of the Efficacy of Imperatorin in Reducing Overactive Bladder Symptoms.
Iwaniak P, Dobrowolski P, Wróbel J, Kluz T, Wdowiak A, Bojar I, Stangel-Wójcikiewicz K, Poleszak E, Jakimiuk A, Misiek M, Zapała Ł, Wróbel A. Iwaniak P, et al. Int J Mol Sci. 2023 Oct 31;24(21):15793. doi: 10.3390/ijms242115793. Int J Mol Sci. 2023. PMID: 37958777 Free PMC article.
Notably, intraperitoneal administration of imperatorin had no discernible effect on urinary bladder function and micturition cycles in normal rats. IMP attenuated the severity of RA-induced OAB. ...
Notably, intraperitoneal administration of imperatorin had no discernible effect on urinary bladder function and micturition cycles i …
Underactive Bladder and Detrusor Underactivity: New Advances and Prospectives.
Wang J, Ren L, Liu X, Liu J, Ling Q. Wang J, et al. Int J Mol Sci. 2023 Oct 24;24(21):15517. doi: 10.3390/ijms242115517. Int J Mol Sci. 2023. PMID: 37958499 Free PMC article. Review.
Underactive bladder (UAB) is a prevalent but under-researched lower urinary tract symptom that typically occurs alongside detrusor underactivity (DU). ...
Underactive bladder (UAB) is a prevalent but under-researched lower urinary tract symptom that typically occurs alongside detr …
Nutritional Considerations for Bladder Storage Conditions in Adult Females.
Gordon B. Gordon B. Int J Environ Res Public Health. 2023 Oct 3;20(19):6879. doi: 10.3390/ijerph20196879. Int J Environ Res Public Health. 2023. PMID: 37835149 Free PMC article. Review.
This study identified and compared clinical guidelines on three urological conditions (interstitial cystitis/bladder pain syndrome (IC/BPS), overactive bladder, and stress urinary incontinence) affecting adult women. METHODS: A three-step process was employed to identify t …
This study identified and compared clinical guidelines on three urological conditions (interstitial cystitis/bladder pain syndrome (IC/BPS), …
Are voiding volumes and frequencies different in the three-day voiding diary in children with lower urinary tract dysfunction?
Ergun R, Sekerci CA, Cetin M, Sahak MY, Yucel S, Tarcan T. Ergun R, et al. Arch Ital Urol Androl. 2023 Oct 3;95(3):11662. doi: 10.4081/aiua.2023.11662. Arch Ital Urol Androl. 2023. PMID: 37791547 Free article.
AIM: The voiding diary (VD) yields crucial insights into voiding volumes (VV), voiding frequency (VF), and management habits in children with lower urinary tract (LUT) dysfunction. It is recommended to be conducted for a minimum of 2 days. ...
AIM: The voiding diary (VD) yields crucial insights into voiding volumes (VV), voiding frequency (VF), and management habits in children wit …
Efficacy of sacral transcutaneous electrical nerve stimulation in patients with overactive bladder refractory to anticholinergic treatment: a prospective multi-center study.
Coronas Soucheiron M, Casal Beloy I, Villalón Ferrero FN, Martín Solé O, Capdevila Vilaró B, González Temprano N, Larreina De la Fuente L, García González M, Carbonell Pradas M, Pérez Bertólez S, Tarrado Castellarnau X, García Aparicio L, Somoza Argibay I. Coronas Soucheiron M, et al. Cir Pediatr. 2023 Oct 1;36(4):180-185. doi: 10.54847/cp.2023.04.14. Cir Pediatr. 2023. PMID: 37818900 Free article. English, Spanish.
Symptom progression was assessed using the voiding calendar and the Pediatric Lower Urinary Tract Symptoms Score (PLUTSS), excluding questions 3 and 4 -referring to enuresis- so that progression of daytime symptoms only (LUTS variable) was analyzed. ...
Symptom progression was assessed using the voiding calendar and the Pediatric Lower Urinary Tract Symptoms Score (PLUTSS), exc …
Therapeutic targets in the brain for overactive bladder: A focus on angiotensin II type 1 receptor.
Shimizu S. Shimizu S. J Pharmacol Sci. 2023 Oct;153(2):69-72. doi: 10.1016/j.jphs.2023.07.005. Epub 2023 Jul 22. J Pharmacol Sci. 2023. PMID: 37640471 Free article. Review.
Angiotensin II (Ang II) is a neuropeptide produced in both brain and peripheral tissues, and Ang II type 1 (AT1) receptors, which are important regions for the micturition reflex, are widely expressed in the cerebral cortex, paraventricular nucleus, solitary tract nucleus, …
Angiotensin II (Ang II) is a neuropeptide produced in both brain and peripheral tissues, and Ang II type 1 (AT1) receptors, which are import …
Use of Fermented Red Clover Isoflavones in the Treatment of Overactive Bladder in Postmenopausal Women: A Randomized, Double-Blinded, Placebo-Controlled Trial.
Villadsen AB, Holm-Jacobsen JN, Prabhala BK, Bundgaard-Nielsen C, Huntjens P, Kornum JB, Glavind K, Leutscher PDC, Christensen LP, Jeppesen PB, Sørensen S, Arenholt LTS. Villadsen AB, et al. Nutrients. 2023 Sep 27;15(19):4165. doi: 10.3390/nu15194165. Nutrients. 2023. PMID: 37836449 Free PMC article. Clinical Trial.
Women filled out the International Consultation on Incontinence Questionnaire Overactive Bladder (ICIQ-OAB) and Urinary Incontinence Short Form (ICIQ-UI-SF), together with a fluid intake and voiding diary. ...Baseline demographics and OAB characteristics were comparable ac …
Women filled out the International Consultation on Incontinence Questionnaire Overactive Bladder (ICIQ-OAB) and Urinary Incontinence …
Comparative assessment of efficacy and safety of approved oral therapies for overactive bladder: a systematic review and network meta-analysis.
He W, Huang G, Cui W, Tian Y, Sun Q, Zhao X, Zhao Y, Li D, Liu X. He W, et al. Int Braz J Urol. 2023 Sep-Oct;49(5):535-563. doi: 10.1590/S1677-5538.IBJU.2023.0158. Int Braz J Urol. 2023. PMID: 37506033 Free PMC article. Review.
Solifenacin 10mg was the most effective in mean daily micturitions and incontinence episodes, solifenacin 5/10mg in mean daily urinary urgency episodes and nocturia episodes, fesoterodine 8mg in urgency incontinence episodes/d and oxybutynin 5mg in voided volume/micturitio …
Solifenacin 10mg was the most effective in mean daily micturitions and incontinence episodes, solifenacin 5/10mg in mean daily urinary
Sleep Disturbance Among Adults With Overactive Bladder: A Cross-sectional Survey.
Lai HH, Walker D, Elsouda D, Lockefeer A, Gallington K, Bacci ED. Lai HH, et al. Urology. 2023 Sep;179:23-31. doi: 10.1016/j.urology.2023.06.014. Epub 2023 Jun 23. Urology. 2023. PMID: 37356462 Free article.
METHODS: A cross-sectional survey of adults with OAB assessed sleep disturbance, nocturia, and depression using patient-reported outcome measures, including the Patient Reported Outcomes Measurement Information System (PROMIS)-29 Profile v2.1 (Sleep Disturbance and Depression dom …
METHODS: A cross-sectional survey of adults with OAB assessed sleep disturbance, nocturia, and depression using patient-reported outcome mea …
[Uroflowmetry: A follow-up tool for neurogenic bladder patients treated by transcutaneous tibial posterior stimulation?].
Viallard L, Voiry C, Maze S, Fontaine S, Kerdraon J, Bonan I, Peyronnet B. Viallard L, et al. Prog Urol. 2023 Aug;33(8-9):421-426. doi: 10.1016/j.purol.2023.02.001. Epub 2023 Mar 13. Prog Urol. 2023. PMID: 36922295 Free article. French.
OBJECTIVE: Neurogenic bladders can suffer from overactivity, underactivity or dyssynergia depending on the level of the initial lesion. These symptoms can lead to severe alterations of the upper urinary tract. One of the first-line treatments is the transcutaneous t …
OBJECTIVE: Neurogenic bladders can suffer from overactivity, underactivity or dyssynergia depending on the level of the initial lesion. Thes …
Overactive bladder syndrome symptoms in youth with abdominal pain-associated disorders of gut-brain interaction.
Friesen HJ, Thompson P, Schurman JV, Colombo JM, Friesen CA. Friesen HJ, et al. Sci Rep. 2023 Jul 8;13(1):11042. doi: 10.1038/s41598-023-37937-w. Sci Rep. 2023. PMID: 37422526 Free PMC article.
As part of standard care, all patients completed a symptom questionnaire regarding gastrointestinal and non-gastrointestinal symptoms including increased urinary frequency, nighttime urination, and urinary urgency. Overall, 54% of patients reported at least one OBS …
As part of standard care, all patients completed a symptom questionnaire regarding gastrointestinal and non-gastrointestinal symptoms includ …
SACRAL NEUROMODULATION IN TREATING OVERACTIVE BLADDER PATIENTS - FIRST-TIME APPLICATION IN CROATIA.
Bakula M, Hauptman D, Hudolin T, Škegro SN, Tudor KI, Bakula B, Kaštelan Ž. Bakula M, et al. Acta Clin Croat. 2023 Jul;62(Suppl2):143-147. doi: 10.20471/acc.2023.62.s2.21. Acta Clin Croat. 2023. PMID: 38966014 Free PMC article. Review.
Indications for SNM include symptoms of overactive bladder (OAB), urinary incontinence, urinary retention, urgency and frequency and, regarding bowel dysfunction, fecal incontinence . ...Over the past two decades, with more than 300 000 treated patients, SNM has con …
Indications for SNM include symptoms of overactive bladder (OAB), urinary incontinence, urinary retention, urgency and frequen …
Treatment of neurogenic detrusor overactivity and overactive bladder with Botox (onabotulinumtoxinA): Development, insights, and impact.
Nitti V, Haag-Molkenteller C, Kennelly M, Chancellor M, Jenkins B, Schurch B. Nitti V, et al. Medicine (Baltimore). 2023 Jul 1;102(S1):e32377. doi: 10.1097/MD.0000000000032377. Medicine (Baltimore). 2023. PMID: 37499088 Free PMC article. Clinical Trial.
NDO often leads to high bladder pressure that may cause upper urinary tract damage and urinary incontinence (UI). Prior to the use of onabotulinumtoxinA, oral anticholinergics and surgical augmentation cystoplasty were the treatment options. ...These randomiz …
NDO often leads to high bladder pressure that may cause upper urinary tract damage and urinary incontinence (UI). Prior …
The pluripotential evolution and journey of Botox (onabotulinumtoxinA).
Brin MF, Blitzer A. Brin MF, et al. Medicine (Baltimore). 2023 Jul 1;102(S1):e32373. doi: 10.1097/MD.0000000000032373. Medicine (Baltimore). 2023. PMID: 37499079 Free PMC article. Review.
Yet another line of research grew out of injections for laryngeal dystonia, whereby clinicians began to explore other sphincters in the gastrointestinal tract and eventually to treatment of pelvic sphincters; many of these sphincters are innervated by autonomic nerves. ...
Yet another line of research grew out of injections for laryngeal dystonia, whereby clinicians began to explore other sphincters in the gast …
Botox (onabotulinumtoxinA) mechanism of action.
Brin MF, Burstein R. Brin MF, et al. Medicine (Baltimore). 2023 Jul 1;102(S1):e32372. doi: 10.1097/MD.0000000000032372. Medicine (Baltimore). 2023. PMID: 37499078 Free PMC article.
Associations of Clinical and Dosimetric Parameters with Urinary Toxicities after Prostate Brachytherapy: A Long-Term Single-Institution Experience.
Ito M, Makita C, Mori T, Takano H, Kumano T, Matsuo M, Iinuma K, Kawase M, Nakane K, Nakano M, Koie T. Ito M, et al. Curr Oncol. 2023 Jun 9;30(6):5680-5689. doi: 10.3390/curroncol30060426. Curr Oncol. 2023. PMID: 37366909 Free PMC article.
Severe and moderate lower urinary tract symptoms (LUTS) were defined as IPSS 20 and 8, respectively; OAB was defined as a nocturnal frequency of 2 and a total OABSS of 3. ...Refining patient selection may further reduce long-term urinary toxicity....
Severe and moderate lower urinary tract symptoms (LUTS) were defined as IPSS 20 and 8, respectively; OAB was defined as a noct …
Mirabegron and Anticholinergics in the Treatment of Overactive Bladder Syndrome: A Meta-analysis.
Sartori LGF, Nunes BM, Farah D, Oliveira LM, Novoa CCT, Sartori MGF, Fonseca MCM. Sartori LGF, et al. Rev Bras Ginecol Obstet. 2023 Jun;45(6):337-346. doi: 10.1055/s-0043-1770093. Epub 2023 Jul 21. Rev Bras Ginecol Obstet. 2023. PMID: 37494577 Free PMC article.
Fewer total adverse events was reported in mirabegron group than in antimuscarinics group [RR 0.93 (0.89-0.98)]. The risk of gastrointestinal tract disorders and dry mouth were lower with mirabegron [RR 0,58 (0.48-0.68); 9375 patients; RR 0.44 (0.35-0.56), 9375 patients, r …
Fewer total adverse events was reported in mirabegron group than in antimuscarinics group [RR 0.93 (0.89-0.98)]. The risk of gastrointestina …
Development of a tool to assess bladder health knowledge, attitudes, and beliefs (BH-KAB).
LaCoursiere DY, Kane Low L, Putnam S, Wyman JF, Newman DK, Cunningham S, Rickey L, Berry A, Gahagan S, Vaughan CP, Brown O, Brady SS; Prevention of Lower Urinary Tract Symptoms (PLUS) Research Consortium. LaCoursiere DY, et al. Neurourol Urodyn. 2023 Jun;42(5):1055-1067. doi: 10.1002/nau.25168. Epub 2023 Mar 11. Neurourol Urodyn. 2023. PMID: 36905331 Free PMC article. Review.
To address this literature gap, the Prevention of Lower Urinary Tract Symptoms (PLUS) research consortium developed an instrument that is being administered in the baseline assessment of the PLUS RISE FOR HEALTH longitudinal study. ...RESULTS: The final 18-item BH-K …
To address this literature gap, the Prevention of Lower Urinary Tract Symptoms (PLUS) research consortium developed an instrum …
Oral anticholinergic drugs versus placebo or no treatment for managing overactive bladder syndrome in adults.
Stoniute A, Madhuvrata P, Still M, Barron-Millar E, Nabi G, Omar MI. Stoniute A, et al. Cochrane Database Syst Rev. 2023 May 9;5(5):CD003781. doi: 10.1002/14651858.CD003781.pub3. Cochrane Database Syst Rev. 2023. PMID: 37160401 Free PMC article. Review.
Compared to placebo, anticholinergics may result in an increase in dry mouth adverse events (RR 3.50, 95% CI 3.26 to 3.75; 66 studies, 38,368 participants; low-certainty evidence), and may result in an increased risk of urinary retention (RR 3.52, 95% CI 2.04 to 6.08; 17 s …
Compared to placebo, anticholinergics may result in an increase in dry mouth adverse events (RR 3.50, 95% CI 3.26 to 3.75; 66 studies, 38,36 …
[The overactive bladder syndrome].
Verjans T, Dewandre M, Keppenne V, Leruth J, Waltregny D. Verjans T, et al. Rev Med Liege. 2023 May;78(5-6):376-380. Rev Med Liege. 2023. PMID: 37350218 Free article. French.
The overactive bladder (OAB) syndrome is defined as urinary urgency, usually with urinary frequency and nocturia, with or without urgency urinary incontinence. ...
The overactive bladder (OAB) syndrome is defined as urinary urgency, usually with urinary frequency and nocturia, with or with …
Urodynamic parameter improvements after mirabegron vs. antimuscarinics agents in non-neurogenic overactive bladder: a systematic review and meta-analysis of treatment effect.
Warli SM, Firsty NN, Natalia D, Velaro AJ, Tala ZZ. Warli SM, et al. Eur Rev Med Pharmacol Sci. 2023 May;27(9):3864-3876. doi: 10.26355/eurrev_202305_32292. Eur Rev Med Pharmacol Sci. 2023. PMID: 37203811 Free article.
Our meta-analysis demonstrated that the improvement of maximum urinary flow rate (Qmax) was more apparent in the mirabegron arm [mean difference (MD), 1.78 (1.31, 2.26); p<0.05] compared to antimuscarinics arm [MD, 0.02 (-2.53, 2.57); p>0.05) as analyzed in random-ef …
Our meta-analysis demonstrated that the improvement of maximum urinary flow rate (Qmax) was more apparent in the mirabegron arm [mean …
Efficacy of peripheral electrical nerve stimulation on improvements of urodynamics and voiding diary in patients with neurogenic lower urinary tract dysfunction: a systematic review and meta-analysis.
Ge Q, Xu H, Fan Z, Li W, Chen Z, Yue D, Xu J, Zhang S, Xue J, Shen B, Wei Z. Ge Q, et al. Int J Surg. 2023 May 1;109(5):1342-1349. doi: 10.1097/JS9.0000000000000168. Int J Surg. 2023. PMID: 37026834 Free PMC article.
BACKGROUND: Peripheral electrical nerve stimulation is a routinely recommended treatment for non-neurogenic overactive bladder but has not been approved for patients with neurogenic lower urinary tract dysfunction (NLUTD). This systematic review and meta-analysis wa …
BACKGROUND: Peripheral electrical nerve stimulation is a routinely recommended treatment for non-neurogenic overactive bladder but has not b …
The effectiveness and safety of oral medications, onabotulinumtoxinA (three doses) and transcutaneous tibial nerve stimulation as non or minimally invasive treatment for the management of neurogenic detrusor overactivity in adults: a systematic review and network meta-analysis.
Chen Y, Peng L, Zhang C, Chen J, Chen J, Shen H, Luo D. Chen Y, et al. Int J Surg. 2023 May 1;109(5):1430-1438. doi: 10.1097/JS9.0000000000000338. Int J Surg. 2023. PMID: 36974676 Free PMC article.
Impact of the suspension of neurogenic detrusor overactivity treatment with botulinum toxin due to the COVID-19 pandemic.
Freitas Ferreira E, Silva R, Ferreira A, Paz Carvalho M, Vale P, Faria F. Freitas Ferreira E, et al. Urologia. 2023 May;90(2):387-394. doi: 10.1177/03915603221113943. Epub 2022 Jul 26. Urologia. 2023. PMID: 35880710 Free PMC article.
A significant increase in the percentage of patients with involuntary urinary loss (p = 0.004) and urgency (p = 0.031) was found. A significant decrease in mean catheterization interval from 4.5 to 3.6 h (p = 0.002) and an increase in daily oxybutynin dosage from 8.5 to 12 …
A significant increase in the percentage of patients with involuntary urinary loss (p = 0.004) and urgency (p = 0.031) was found. A s …
Molecular Mechanisms of Neurogenic Lower Urinary Tract Dysfunction after Spinal Cord Injury.
Shimizu N, Saito T, Wada N, Hashimoto M, Shimizu T, Kwon J, Cho KJ, Saito M, Karnup S, de Groat WC, Yoshimura N. Shimizu N, et al. Int J Mol Sci. 2023 Apr 26;24(9):7885. doi: 10.3390/ijms24097885. Int J Mol Sci. 2023. PMID: 37175592 Free PMC article. Review.
This article provides a synopsis of current progress made in fundamental studies of lower urinary tract dysfunction (LUTD) after spinal cord injury (SCI) above the sacral level. ...These neural systems control the action of two functional units in the LUT: the ur
This article provides a synopsis of current progress made in fundamental studies of lower urinary tract dysfunction (LUTD) aft …
Study design of a phase 4, real-world study (COMPOSUR) to evaluate vibegron in patients with overactive bladder.
Dmochowski RR, Rovner ES, Kennelly MJ, Newman DK, Abedinzadeh L, Snyder D, Thomas E, Haag-Molkenteller C, Rosenberg MT. Dmochowski RR, et al. BMC Urol. 2023 Apr 24;23(1):64. doi: 10.1186/s12894-023-01240-7. BMC Urol. 2023. PMID: 37095473 Free PMC article. Clinical Trial.
BACKGROUND: Overactive bladder (OAB) is defined as urinary urgency accompanied by frequency and nocturia, with or without urge urinary incontinence (UUI). ...
BACKGROUND: Overactive bladder (OAB) is defined as urinary urgency accompanied by frequency and nocturia, with or without urge uri
TReating Incontinence for Underlying Mental and Physical Health (TRIUMPH): a study protocol for a multicenter, double-blinded, randomized, 3-arm trial to evaluate the multisystem effects of pharmacologic treatment strategies for urgency-predominant urinary incontinence in ambulatory older women.
Huang AJ, Walter LC, Yaffe K, Vittinghoff E, Kornblith E, Schembri M, Chang A, Subak LL. Huang AJ, et al. Trials. 2023 Apr 21;24(1):287. doi: 10.1186/s13063-023-07279-z. Trials. 2023. PMID: 37085880 Free PMC article.
BACKGROUND: Urgency-type urinary incontinence affects one in four older community-dwelling women and overlaps with other common aging-associated health syndromes such as cognitive impairment, physical mobility impairment, and depression. ...Women aged 60 years and older (t …
BACKGROUND: Urgency-type urinary incontinence affects one in four older community-dwelling women and overlaps with other common aging …
The biopsychosocial impacts of anxiety on overactive bladder in women.
Reynolds WS, McKernan LC, Dmochowski RR, Bruehl S. Reynolds WS, et al. Neurourol Urodyn. 2023 Apr;42(4):778-784. doi: 10.1002/nau.25152. Epub 2023 Feb 13. Neurourol Urodyn. 2023. PMID: 36780135 Free PMC article.
Analyses focused on patient-reported questionnaires assessing urinary symptom severity and quality of life, psychological stress symptoms, general somatic symptoms, and results of quantitative sensory testing (QST), including temporal summation to heat pain (TSP). ...RESUL …
Analyses focused on patient-reported questionnaires assessing urinary symptom severity and quality of life, psychological stress symp …
Assessment of bladder pressure and discomfort symptoms: How do overactive bladder differ from interstitial cystitis/bladder pain syndrome patients?
Gousse A, Vetter J, Lai HH. Gousse A, et al. BMC Urol. 2023 Mar 30;23(1):53. doi: 10.1186/s12894-022-01164-8. BMC Urol. 2023. PMID: 36997906 Free PMC article.
METHODS: IC/BPS and OAB patients rated their bladder pain, pressure, discomfort, and urinary urgency on separate 0-10 numeric rating scales (NRS). Their NRS ratings were compared between IC/BPS and OAB, and Pearson correlations were performed. RESULTS: Among IC/BPS patient …
METHODS: IC/BPS and OAB patients rated their bladder pain, pressure, discomfort, and urinary urgency on separate 0-10 numeric rating …
Evaluation of the association between asthma and non-neurogenic urinary incontinence in children; a case-control study.
Ziaei E, Dorreh F, Yousefichaijan P, Sarmadian R, Sajjadi N, Kahbazi M. Ziaei E, et al. BMC Pediatr. 2023 Mar 30;23(1):141. doi: 10.1186/s12887-023-03958-7. BMC Pediatr. 2023. PMID: 36997891 Free PMC article.
Asthma can lead to sleep disorders and psychiatric issues, which are often accompanied by urinary incontinence in children. Furthermore, several studies have shown a relationship between allergic diseases and urinary incontinence. ...Moreover, the association betwee …
Asthma can lead to sleep disorders and psychiatric issues, which are often accompanied by urinary incontinence in children. Furthermo …
Intravesical Injection of Botulinum Toxin Type A in Men without Bladder Outlet Obstruction and Post-Deobstructive Prostate Surgery.
Lee HY, Kuo HC. Lee HY, et al. Toxins (Basel). 2023 Mar 15;15(3):221. doi: 10.3390/toxins15030221. Toxins (Basel). 2023. PMID: 36977112 Free PMC article. Review.
Two studies focused on patients who had undergone prior surgery for stress urinary incontinence, including male sling and artificial urethral sphincter surgery. ...
Two studies focused on patients who had undergone prior surgery for stress urinary incontinence, including male sling and artificial …
Treating Lower Urinary Tract Symptoms in Older Adults: Intravesical Options.
Ganguly A, Tyagi S, Chermansky C, Kanai A, Beckel J, Hashimoto M, Cho KJ, Chancellor M, Kaufman J, Yoshimura N, Tyagi P. Ganguly A, et al. Drugs Aging. 2023 Mar;40(3):241-261. doi: 10.1007/s40266-023-01009-5. Epub 2023 Mar 6. Drugs Aging. 2023. PMID: 36879156 Free PMC article. Review.
This article provides an overview of the diagnosis and the treatment of lower urinary tract symptoms in older adults complicated by the neurodegenerative changes in the micturition reflex and further confounded by age-related decline in hepatic and renal clearance r …
This article provides an overview of the diagnosis and the treatment of lower urinary tract symptoms in older adults complicat …
Mechanism of traditional Chinese medicine in treating overactive bladder.
Liao Y, Du X, Fu Y, Liu L, Wei J, An Q, Luo X, Gao F, Jia S, Chang Y, Guo M, Liu H. Liao Y, et al. Int Urol Nephrol. 2023 Mar;55(3):489-501. doi: 10.1007/s11255-022-03434-8. Epub 2022 Dec 7. Int Urol Nephrol. 2023. PMID: 36479677 Free PMC article. Review.
Impaired insulin signaling at the bladder mucosa facilitates metabolic syndrome-associated bladder overactivity in rats with maternal and post-weaning fructose exposure.
Lee WC, Wu KLH, Tain YL, Leu S, Cheng YT, Chan JYH. Lee WC, et al. J Formos Med Assoc. 2023 Mar;122(3):258-266. doi: 10.1016/j.jfma.2022.09.013. Epub 2022 Oct 4. J Formos Med Assoc. 2023. PMID: 36207218 Free article.
The canonical signalling pathway of insulin was evaluated in the bladder mucosal using Western blotting. Levels of detrusor cGMP and urinary NO(2) plus NO(3) were measured. RESULTS: Male offspring with any fructose exposure presents traits of MetS and bladder overactivity. …
The canonical signalling pathway of insulin was evaluated in the bladder mucosal using Western blotting. Levels of detrusor cGMP and urin
Toileting behaviors, urinary cues, overactive bladder, and urinary incontinence in older women.
O'Connell KA, Nicholas TB, Palmer MH. O'Connell KA, et al. Int Urogynecol J. 2023 Mar;34(3):707-716. doi: 10.1007/s00192-022-05228-z. Epub 2022 May 19. Int Urogynecol J. 2023. PMID: 35588320 Free PMC article.
INTRODUCTION AND HYPOTHESIS: Overactive bladder (OAB) and urinary incontinence (UI) are prevalent in older women. We investigated relations of toileting behaviors and urinary urge cues to OAB and UI in women 65 years. ...Urinary urge cues partially mediated t …
INTRODUCTION AND HYPOTHESIS: Overactive bladder (OAB) and urinary incontinence (UI) are prevalent in older women. We investigated rel …
The Relationship between the Presence of an Earlobe Crease and Overactive Bladder: A Cross-Sectional Case-Controlled Study.
Ueda Y, Matsuo T, Kawada K, Ito H, Mitsunari K, Ohba K, Imamura R. Ueda Y, et al. Medicina (Kaunas). 2023 Feb 28;59(3):476. doi: 10.3390/medicina59030476. Medicina (Kaunas). 2023. PMID: 36984477 Free PMC article.
The relationship between these findings and the presence or absence and severity of EC was also examined. A score of 2 points on OABSS question 3 (urinary urgency), with a total score of 3 points, indicated OAB. Results: We analyzed 246 participants, including 120 (48.8%) …
The relationship between these findings and the presence or absence and severity of EC was also examined. A score of 2 points on OABSS quest …
Role of Urological Botulinum Toxin-A Injection for Overactive Bladder and Voiding Dysfunction in Patients with Parkinson's Disease or Post-Stroke.
Hu JC, Hsu LN, Lee WC, Chuang YC, Wang HJ. Hu JC, et al. Toxins (Basel). 2023 Feb 17;15(2):166. doi: 10.3390/toxins15020166. Toxins (Basel). 2023. PMID: 36828479 Free PMC article. Review.
A high proportion of patients with PD and post-stroke develop neurogenic detrusor overactivity (nDO) and then develop urinary incontinence and overactive bladder (OAB) symptoms. This study aimed to disclose the safety and efficacy of BoNT-A injection in treating bladder an …
A high proportion of patients with PD and post-stroke develop neurogenic detrusor overactivity (nDO) and then develop urinary inconti …
Involvement of Mast-Cell-Tryptase- and Protease-Activated Receptor 2-Mediated Signaling and Urothelial Barrier Dysfunction with Reduced Uroplakin II Expression in Bladder Hyperactivity Induced by Chronic Bladder Ischemia in the Rat.
Akaihata H, Matsuoka K, Hata J, Harigane Y, Yaginuma K, Endo Y, Imai H, Matsuoka Y, Onagi A, Tanji R, Honda-Takinami R, Hoshi S, Koguchi T, Sato Y, Kataoka M, Uemura M, Igawa Y, Kojima Y. Akaihata H, et al. Int J Mol Sci. 2023 Feb 16;24(4):3982. doi: 10.3390/ijms24043982. Int J Mol Sci. 2023. PMID: 36835398 Free PMC article.
Establishment of an overactive bladder model in mice.
Lv T, Zhong S, Guo X. Lv T, et al. BMC Urol. 2023 Feb 13;23(1):19. doi: 10.1186/s12894-023-01181-1. BMC Urol. 2023. PMID: 36782229 Free PMC article.
BACKGROUND: Overactive bladder (OAB) is a syndrome characterized by symptoms of urinary urgency, often accompanied by frequent urination and nocturia or urge incontinence. ...
BACKGROUND: Overactive bladder (OAB) is a syndrome characterized by symptoms of urinary urgency, often accompanied by frequent urinat …
Overactive bladder with urodynamic study-induced bladder pain: An overactive bladder subtype with symptoms similar to those of interstitial cystitis/painful bladder syndrome.
Mu HY, Wu MP, Wang IT, Wu JC, Chin HY. Mu HY, et al. Medicine (Baltimore). 2023 Feb 10;102(6):e32790. doi: 10.1097/MD.0000000000032790. Medicine (Baltimore). 2023. PMID: 36820564 Free PMC article.
Overactive bladder (OAB) and interstitial cystitis/painful bladder syndrome (IC/PBS) are 2 lower urinary tract disorders with urgency and bladder pain for diagnosis and with several other shared symptoms. ...The OAB-BP group and the IC/PBS group reported more intrus …
Overactive bladder (OAB) and interstitial cystitis/painful bladder syndrome (IC/PBS) are 2 lower urinary tract disorders with …
Molecular Mechanism Operating in Animal Models of Neurogenic Detrusor Overactivity: A Systematic Review Focusing on Bladder Dysfunction of Neurogenic Origin.
Ferreira A, Nascimento D, Cruz CD. Ferreira A, et al. Int J Mol Sci. 2023 Feb 7;24(4):3273. doi: 10.3390/ijms24043273. Int J Mol Sci. 2023. PMID: 36834694 Free PMC article. Review.
Neurogenic detrusor overactivity (NDO) is a severe lower urinary tract disorder, characterized by urinary urgency, retention, and incontinence, as a result of a neurologic lesion that results in damage in neuronal pathways controlling micturition. ...Animal m …
Neurogenic detrusor overactivity (NDO) is a severe lower urinary tract disorder, characterized by urinary urgency, rete …
Sacral neuromodulation treatment for urinary voiding dysfunctions: results of treatment with the largest single-center series in a tertiary referral center in Turkey.
Kütükoğlu MU, Altuntaş T, Şahin B, Onur AR. Kütükoğlu MU, et al. Turk J Med Sci. 2023 Feb;53(1):206-210. doi: 10.55730/1300-0144.5575. Epub 2023 Feb 22. Turk J Med Sci. 2023. PMID: 36945940 Free PMC article.
The aim of this study was to present our experience with SNM in a tertiary referral center with the largest number of patients and review the safety and efficacy of the procedure. METHODS: A total of 42 patients with refractory lower urinary tract symptoms were incl …
The aim of this study was to present our experience with SNM in a tertiary referral center with the largest number of patients and review th …
Mixed urinary incontinence: Are there effective treatments?
Game X, Dmochowski R, Robinson D. Game X, et al. Neurourol Urodyn. 2023 Feb;42(2):401-408. doi: 10.1002/nau.25065. Epub 2022 Oct 23. Neurourol Urodyn. 2023. PMID: 36762411 Free PMC article.
The aim of this debate article is to discuss whether effective treatments are available for mixed urinary incontinence (MUI). Because patients with MUI have both stress and urgency urinary incontinence (SUI and UUI) episodes and current treatment guidelines currentl …
The aim of this debate article is to discuss whether effective treatments are available for mixed urinary incontinence (MUI). Because …
Pre- versus Post-Menopausal Onset of Overactive Bladder and the Response to Vaginal Estrogen Therapy: A Prospective Study.
Baruch Y, Torella M, De Bastiani S, Meschia M, Candiani M, Colacurci N, Salvatore S. Baruch Y, et al. Medicina (Kaunas). 2023 Jan 27;59(2):245. doi: 10.3390/medicina59020245. Medicina (Kaunas). 2023. PMID: 36837446 Free PMC article.
Background and Objectives: This study examined the utility of local estrogen therapy for improving urinary symptoms in women diagnosed with Overactive Bladder allied to the time of onset of urinary symptoms whether pre- or post-menopausal. ...Exclusion criteria incl …
Background and Objectives: This study examined the utility of local estrogen therapy for improving urinary symptoms in women diagnose …
Intravesical Injection of Botulinum Toxin Type A in Patients with Refractory Overactive Bladder-Results between Young and Elderly Populations, and Factors Associated with Unfavorable Outcomes.
Ou YC, Kao YL, Ho YH, Wu KY, Kuo HC. Ou YC, et al. Toxins (Basel). 2023 Jan 19;15(2):95. doi: 10.3390/toxins15020095. Toxins (Basel). 2023. PMID: 36828410 Free PMC article.
The prevalence rates of common unfavorable outcomes, including urinary tract infections, large post-void residual urine volume, and urinary retention, were 9.2%, 27.7%, and 12.3%, respectively. ...
The prevalence rates of common unfavorable outcomes, including urinary tract infections, large post-void residual urine volume …
Efficacy of abobotulinumtoxinA versus onabotulinumtoxinA for the treatment of refractory neurogenic detrusor overactivity: a systematic review and indirect treatment comparison.
Cruz F, Danchenko N, Fahrbach K, Freitag A, Tarpey J, Whalen J. Cruz F, et al. J Med Econ. 2023 Jan-Dec;26(1):200-207. doi: 10.1080/13696998.2023.2165366. J Med Econ. 2023. PMID: 36647624 Free article.
The safety outcome was the proportion of patients with treatment-emergent urinary tract infections (TE-UTIs) during follow-up. Subgroup/sensitivity analyses were performed to investigate the impact of heterogeneity. ...Neurogenic detrusor overactivity (NDO) is a con …
The safety outcome was the proportion of patients with treatment-emergent urinary tract infections (TE-UTIs) during follow-up. …
Treatment patterns in women with urinary urgency and/or urgency urinary incontinence in the symptoms of Lower Urinary Tract Dysfunction Research Network Observational Cohort Study.
Bretschneider CE, Liu Q, Smith AR, Kirkali Z, Amundsen CL, Lai H, Geynisman-Tan J, Kirby A, Cameron AP, Helmuth ME, Griffith JW, Jelovsek JE; Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) Observational Cohort Study Group. Bretschneider CE, et al. Neurourol Urodyn. 2023 Jan;42(1):194-204. doi: 10.1002/nau.25067. Epub 2022 Oct 23. Neurourol Urodyn. 2023. PMID: 36579974 Free PMC article.
OBJECTIVES: To describe treatment patterns for women with bothersome urinary urgency (UU) and/or urgency urinary incontinence (UUI) presenting to specialty care over 1 year. STUDY DESIGN: The Symptoms of Lower Urinary Tract Dysfunction Research Network …
OBJECTIVES: To describe treatment patterns for women with bothersome urinary urgency (UU) and/or urgency urinary incontinence …
Overactive Bladder Patients With and Without Urgency Incontinence: A Spectrum of One Condition or Different Phenotypes?
Torosis M, Jackson N, Nitti V, Ackerman AL. Torosis M, et al. Urogynecology (Phila). 2023 Jan 1;29(1):33-40. doi: 10.1097/SPV.0000000000001254. Epub 2022 Oct 2. Urogynecology (Phila). 2023. PMID: 36548103 Free PMC article.
OBJECTIVES: The aim of this study was to define fundamental and unique presenting features of patients exhibiting storage lower urinary tract symptoms (LUTS) with urgency incontinence (OAB-wet) and patients without urgency incontinence (OAB-dry). STUDY DESIGN: This …
OBJECTIVES: The aim of this study was to define fundamental and unique presenting features of patients exhibiting storage lower urinary
Reduced versus standard intradetrusor OnabotulinumtoxinA injections for treatment of overactive bladder.
DiCarlo-Meacham AM, Dengler KL, Welch EK, Brooks DI, Gruber DD, Osborn DJ, Scarlotta L, Vaccaro CM. DiCarlo-Meacham AM, et al. Neurourol Urodyn. 2023 Jan;42(1):366-374. doi: 10.1002/nau.25107. Epub 2022 Dec 1. Neurourol Urodyn. 2023. PMID: 36455284 Free PMC article. Clinical Trial.
The primary outcome was treatment efficacy as determined by Overactive Bladder Questionnaire-Short Form with a noninferiority margin of 15 points. Secondary outcomes were incidence of urinary tract infection and urinary retention requiring catheterization. .. …
The primary outcome was treatment efficacy as determined by Overactive Bladder Questionnaire-Short Form with a noninferiority margin of 15 p …
AbobotulinumtoxinA is effective in patients with urinary incontinence due to neurogenic detrusor overactivity regardless of spinal cord injury or multiple sclerosis etiology: Pooled analysis of two phase III randomized studies (CONTENT1 and CONTENT2).
Denys P, Castaño Botero JC, Vita Nunes RL, Wachs B, Mendes Gomes C, Krivoborodov G, Tu LM, Del-Popolo G, Thompson C, Vilain C, Volteau M, Kennelly M; Dysport CONTENT program group. Denys P, et al. Neurourol Urodyn. 2023 Jan;42(1):153-167. doi: 10.1002/nau.25062. Epub 2022 Nov 2. Neurourol Urodyn. 2023. PMID: 36321799 Free PMC article. Clinical Trial.
Median time-to-retreatment was longer in patients with MS (48-62 weeks across doses) than those with SCI (39-44 weeks). Safety data were similar between etiologies. Urinary tract infection was the most frequent adverse event; similar numbers were reported across tre …
Median time-to-retreatment was longer in patients with MS (48-62 weeks across doses) than those with SCI (39-44 weeks). Safety data were sim …
Factors associated with low-compliance bladder in end-stage renal disease patients and development of a clinical prediction model for urodynamic evaluation: the DUDi score.
Tangpaitoon T, Swatesutipun V. Tangpaitoon T, et al. Int Urol Nephrol. 2023 Jan;55(1):75-84. doi: 10.1007/s11255-022-03399-8. Epub 2022 Oct 28. Int Urol Nephrol. 2023. PMID: 36307573 Free PMC article.

Demographics data, predictor factors related to the bladder compliance such as underlying disease of the lower urinary tract disease (LUTD), duration of urine < 250 mL/day, type and duration of renal replacement therapy (RRT), urine volume per day and urodynamic

Demographics data, predictor factors related to the bladder compliance such as underlying disease of the lower urinary tract d …
Are we underestimating urinary retention following intravesical onabotulinumtoxinA in women with overactive bladder and a history of prior pelvic surgery?
Holmes A, Kelsey E, Wombwell A, Molesworth C, McLeod K. Holmes A, et al. Neurourol Urodyn. 2023 Jan;42(1):106-112. doi: 10.1002/nau.25054. Epub 2022 Oct 2. Neurourol Urodyn. 2023. PMID: 36183370 Free PMC article.
AIMS: This study's purpose is to review the rates of urinary retention requiring intermittent catheterization (IC) post intravesical OnabotulinumtoxinA (BTN/A) injection for idiopathic overactive bladder from a single practicing specialist urological surgeon. ...Of patient …
AIMS: This study's purpose is to review the rates of urinary retention requiring intermittent catheterization (IC) post intravesical …
Effect of Vitamin D Supplementation on Overactive Bladder and Urinary Incontinence Symptoms in Older Men: Ancillary Findings From a Randomized Trial.
Markland AD, Vaughan CP, Huang AJ, Kim E, Bubes VY, Tangpricha V, Buring JR, Lee IM, Cook NR, Manson JE, Grodstein F. Markland AD, et al. J Urol. 2023 Jan;209(1):243-252. doi: 10.1097/JU.0000000000002942. Epub 2022 Sep 6. J Urol. 2023. PMID: 36067369 Free PMC article. Clinical Trial.
PURPOSE: Our goal was to evaluate vitamin D supplementation for preventing or treating overactive bladder and urinary incontinence in men. MATERIALS AND METHODS: Ancillary study of men aged 55 years in VITAL (VITamin D and OmegA-3 TriaL). Randomized treatments included: vi …
PURPOSE: Our goal was to evaluate vitamin D supplementation for preventing or treating overactive bladder and urinary incontinence in …
Sacral neuromodulation for overactive bladder using the InterStim and BetterStim systems.
Meng L, Tian Z, Zhang Y, Wang J, Liao L, Chen G, Tian X, Ma L, Li Y, Shi B, Zhang Y, Ling Q, Zhang P, Wei Z, Zhong T, Xu Z, Li J, Luo D. Meng L, et al. Sci Rep. 2022 Dec 24;12(1):22299. doi: 10.1038/s41598-022-26267-y. Sci Rep. 2022. PMID: 36566332 Free PMC article.

Specifically, the urination frequency (all P < 0.001), average voiding volume (all P < 0.001), and average urinary leakage (InterStim, P < 0.05; BetterStim, P < 0.01) in both groups significantly improved at different periods during treatment. ...Urination freq

Specifically, the urination frequency (all P < 0.001), average voiding volume (all P < 0.001), and average urinary leakage (Int

Spinal Cord Injury Causes Marked Tissue Rearrangement in the Urethra-Experimental Study in the Rat.
Ferreira A, Chambel SS, Avelino A, Cruz CD. Ferreira A, et al. Int J Mol Sci. 2022 Dec 15;23(24):15951. doi: 10.3390/ijms232415951. Int J Mol Sci. 2022. PMID: 36555592 Free PMC article.
Traumatic spinal cord injury (SCI) results in the time-dependent development of urinary impairment due to neurogenic detrusor overactivity (NDO) and detrusor-sphincter-dyssynergia (DSD). ...It is likely that these changes will affect urethral function and contribute to SCI …
Traumatic spinal cord injury (SCI) results in the time-dependent development of urinary impairment due to neurogenic detrusor overact …
Natural history of lower urinary tract symptoms in treatment-seeking women with pelvic organ prolapse; the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN).
Kowalski JT, Wiseman JB, Smith AR, Helmuth ME, Cameron A, DeLancey JOL, Hendrickson WK, Jelovsek JE, Kirby A, Kreder K, Lai HH, Mueller M, Siddiqui N, Bradley CS. Kowalski JT, et al. Am J Obstet Gynecol. 2022 Dec;227(6):875.e1-875.e12. doi: 10.1016/j.ajog.2022.07.038. Epub 2022 Aug 5. Am J Obstet Gynecol. 2022. PMID: 35934118 Free PMC article.
Secondary aims were to explore associations between lower urinary tract symptoms and prolapse treatment. We hypothesized that: (1) prolapse is associated with the presence of lower urinary tract symptoms, (2) lower urinary tract symptoms …
Secondary aims were to explore associations between lower urinary tract symptoms and prolapse treatment. We hypothesized that: …
Adverse events related to antimuscarinics and beta-3-agonist: "real-life" data from the Eudra-Vigilance Database.
DE Nunzio C, Nacchia A, Gravina C, Turchi B, Gallo G, Trucchi A, DI Giacomo F, Disabato G, Franco A, Rovesti L, Lombardo R, Cicione A, Tubaro A. DE Nunzio C, et al. Minerva Urol Nephrol. 2022 Dec;74(6):761-779. doi: 10.23736/S2724-6051.22.04849-2. Epub 2022 Jun 16. Minerva Urol Nephrol. 2022. PMID: 35708534 Free article.
RESULTS: Overall, 2313 AEs were reported for oxybutinin, 5129 for solifenacin, 2483 for tolterodine, 3523 for fesoterodine, 787 for trospium, 621 for propiverine and 7213 for mirabegron. Urinary retention was higher for fesoterodine (43%) and tolterodine (23%) when compare …
RESULTS: Overall, 2313 AEs were reported for oxybutinin, 5129 for solifenacin, 2483 for tolterodine, 3523 for fesoterodine, 787 for trospium …
Efficacy and safety of skin-adhesive low-level light therapy for overactive bladder: a Phase III study.
Hwang WY, Kim YB, Lee SR, Suh DH, Kim K, No JH. Hwang WY, et al. Int Urogynecol J. 2022 Dec;33(12):3573-3580. doi: 10.1007/s00192-022-05153-1. Epub 2022 Apr 7. Int Urogynecol J. 2022. PMID: 35389054 Free PMC article. Clinical Trial.
The primary outcome was the change in the mean daily number of urge urinary incontinence (UUI) episodes between baseline and 12 weeks. ...RESULTS: Compared with those in the sham group, the numbers of UUI and urinary incontinence episodes in the LLLT group were sign …
The primary outcome was the change in the mean daily number of urge urinary incontinence (UUI) episodes between baseline and 12 weeks …
Effect of vacation on urinary symptoms in health care workers: an Italian multicenter study.
DE Nunzio C, Nacchia A, Lombardo R, Brassetti A, Sica A, Baldassarri V, Guarnotta G, Al Salhi Y, Tuderti G, Li Marzi V, Finazzi Agrò E, Pastore A, Carbone A, Simone G, Tubaro A; publications committee of Italian Society of Urodynamics (SIUD). DE Nunzio C, et al. Minerva Urol Nephrol. 2022 Dec;74(6):755-760. doi: 10.23736/S2724-6051.21.04274-0. Epub 2021 Mar 29. Minerva Urol Nephrol. 2022. PMID: 33781024 Free article.
Demographic and clinical characteristics of health care workers (i.e. age, smoking status, medical history) were collected. Lower urinary tract symptoms (LUTS) and work related quality of life were assessed before and after vacation with validated questionnaires: Ov …
Demographic and clinical characteristics of health care workers (i.e. age, smoking status, medical history) were collected. Lower urinary
Feasibility and clinical implications of 3-day bladder diary derived classification of female storage lower urinary tract symptoms.
Hsiao SM, Lin HH. Hsiao SM, et al. Sci Rep. 2022 Nov 25;12(1):20339. doi: 10.1038/s41598-022-24539-1. Sci Rep. 2022. PMID: 36434107 Free PMC article.
Our aim was to assess the feasibility of a bladder diary (BD) classification as a surrogate for urodynamic studies in women with storage lower urinary tract symptoms. A total of 3823 women who underwent urodynamic studies were reviewed. ...
Our aim was to assess the feasibility of a bladder diary (BD) classification as a surrogate for urodynamic studies in women with storage low …
Unraveling the impact of Lactobacillus spp. and other urinary microorganisms on the efficacy of mirabegron in female patients with overactive bladder.
Zhou Z, Qiu Y, Li K, Sun Q, Xie M, Huang P, Yu Y, Wang B, Xue J, Zhu Z, Feng Z, Zhao J, Wu P. Zhou Z, et al. Front Cell Infect Microbiol. 2022 Nov 14;12:1030315. doi: 10.3389/fcimb.2022.1030315. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 36452303 Free PMC article.
To address this issue, more and more researchers are examining the relationship between OAB treatment and urinary microecology. In this study, we sought to determine whether differences in treatment efficacy were related to microbiome diversity and composition as well as t …
To address this issue, more and more researchers are examining the relationship between OAB treatment and urinary microecology. In th …
Efficacy and safety of combination of mirabegron and solifenacin in patients with double-J stent related overactive bladder: a prospective study.
Tang QL, Zhou S, Liu YQ, Wu J, Tao RZ. Tang QL, et al. Sci Rep. 2022 Nov 7;12(1):18844. doi: 10.1038/s41598-022-23795-5. Sci Rep. 2022. PMID: 36344629 Free PMC article. Clinical Trial.
One-hundred and nine cases in the combination group accepted mirabegron and solifenacin therapy and 110 cases as control only accepted solifenacin therapy. The lower urinary tract symptoms and overactive bladder questionnaire (OAB-q) health-related quality of life ( …
One-hundred and nine cases in the combination group accepted mirabegron and solifenacin therapy and 110 cases as control only accepted solif …
Associations Between Unmet Social Needs and Overactive Bladder.
Sebesta EM, Gleicher S, Kaufman MR, Dmochowski RR, Reynolds WS. Sebesta EM, et al. J Urol. 2022 Nov;208(5):1106-1115. doi: 10.1097/JU.0000000000002841. Epub 2022 Sep 15. J Urol. 2022. PMID: 36106450 Free PMC article.
MATERIALS AND METHODS: A community-based sample of adults was recruited electronically to complete questionnaires on clinical and demographic information, urinary symptoms and unmet social needs. Multivariable logistic regression was used to assess for association between …
MATERIALS AND METHODS: A community-based sample of adults was recruited electronically to complete questionnaires on clinical and demographi …
The cumulative effect of unmet social needs on noncancerous genitourinary conditions and severity of lower urinary tract symptoms.
Anne Zwaschka T, Sebesta EM, Gleicher S, Kaufman MR, Dmochowski RR, Reynolds WS. Anne Zwaschka T, et al. Neurourol Urodyn. 2022 Nov;41(8):1862-1871. doi: 10.1002/nau.25038. Epub 2022 Sep 6. Neurourol Urodyn. 2022. PMID: 36066087 Free PMC article.
MATERIALS AND METHODS: A community-based sample of United States adults was recruited electronically to complete questionnaires on clinical and demographic information, urinary symptoms, and social needs. Logistic regression was used to assess the effect between the number …
MATERIALS AND METHODS: A community-based sample of United States adults was recruited electronically to complete questionnaires on clinical …
Third-line therapy for overactive bladder in the elderly: Nuances and considerations.
Zillioux J, Slopnick EA, Vasavada SP. Zillioux J, et al. Neurourol Urodyn. 2022 Nov;41(8):1967-1974. doi: 10.1002/nau.24965. Epub 2022 May 29. Neurourol Urodyn. 2022. PMID: 35645033 Free PMC article. Review.
RESULTS: While limited, available studies show all three third-line therapies are efficacious in older populations and there is no data to support one option over another. BTX-A likely has a higher risk of urinary tract infection and retention in older compared to y …
RESULTS: While limited, available studies show all three third-line therapies are efficacious in older populations and there is no data to s …
Stimulation of the Tibial nerve Repetitively to Improve Incontinence in Parkinson's Electronically (STRIPE trial): a randomised control trial of tibial nerve stimulation for bladder symptoms in Parkinson's disease using a self-contained wearable device.
Smith MD, Tenison E, Drake MJ, Ben-Shlomo Y, Henderson EJ. Smith MD, et al. Trials. 2022 Oct 28;23(1):912. doi: 10.1186/s13063-022-06827-3. Trials. 2022. PMID: 36307874 Free PMC article. Clinical Trial.
Urinary brain-derived neurotrophic factor and nerve growth factor as noninvasive biomarkers of overactive bladder in children.
Colic M, Rogic D, Lenicek Krleza J, Kozmar A, Stemberger Maric L, Abdovic S. Colic M, et al. Biochem Med (Zagreb). 2022 Oct 1;32(3):030706. doi: 10.11613/BM.2022.030706. Epub 2022 Oct 1. Biochem Med (Zagreb). 2022. PMID: 36277428 Free PMC article.
INTRODUCTION: Overactive bladder (OAB) is the most common urinary disorder and the leading cause of functional daytime intermittent urinary incontinence in children. The aim of this study was to determine whether urinary brain-derived neurotrophic factor (BDN …
INTRODUCTION: Overactive bladder (OAB) is the most common urinary disorder and the leading cause of functional daytime intermittent …
COVID-19 associated lower urinary tract symptoms in children.
Tiryaki S, Egil O, Birbilen AZ, Buyukcam A. Tiryaki S, et al. J Pediatr Urol. 2022 Oct;18(5):680.e1-680.e7. doi: 10.1016/j.jpurol.2022.08.018. Epub 2022 Sep 6. J Pediatr Urol. 2022. PMID: 36153241 Free PMC article.
INTRODUCTION: SARS-COV-2 is associated with unexpected symptoms. Several studies in adults reported urinary frequency with COVID-19. The aim of this study is to reveal lower urinary tract symptoms associated with COVID-19 (CALUTS) in children. ...CONCLUSIONS: …
INTRODUCTION: SARS-COV-2 is associated with unexpected symptoms. Several studies in adults reported urinary frequency with COVID-19. …