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Page 1
Discovery of Small-Molecule Nonfluorescent Inhibitors of Fluorogen-Fluorogen Activating Protein Binding Pair.
Wu Y, Stauffer SR, Stanfield RL, Tapia PH, Ursu O, Fisher GW, Szent-Gyorgyi C, Evangelisti A, Waller A, Strouse JJ, Carter MB, Bologa C, Gouveia K, Poslusney M, Waggoner AS, Lindsley CW, Jarvik JW, Sklar LA. Wu Y, et al. Among authors: ursu o. J Biomol Screen. 2016 Jan;21(1):74-87. doi: 10.1177/1087057115609145. Epub 2015 Oct 6. J Biomol Screen. 2016. PMID: 26442911
A selective ATP-binding cassette subfamily G member 2 efflux inhibitor revealed via high-throughput flow cytometry.
Strouse JJ, Ivnitski-Steele I, Khawaja HM, Perez D, Ricci J, Yao T, Weiner WS, Schroeder CE, Simpson DS, Maki BE, Li K, Golden JE, Foutz TD, Waller A, Evangelisti AM, Young SM, Chavez SE, Garcia MJ, Ursu O, Bologa CG, Carter MB, Salas VM, Gouveia K, Tegos GP, Oprea TI, Edwards BS, Aubé J, Larson RS, Sklar LA. Strouse JJ, et al. Among authors: ursu o. J Biomol Screen. 2013 Jan;18(1):26-38. doi: 10.1177/1087057112456875. Epub 2012 Aug 24. J Biomol Screen. 2013. PMID: 22923785 Free PMC article.
Conformational mAb as a tool for integrin ligand discovery.
Njus BH, Chigaev A, Waller A, Wlodek D, Ostopovici-Halip L, Ursu O, Wang W, Oprea TI, Bologa CG, Sklar LA. Njus BH, et al. Among authors: ursu o. Assay Drug Dev Technol. 2009 Oct;7(5):507-15. doi: 10.1089/adt.2009.0203. Assay Drug Dev Technol. 2009. PMID: 19754304 Free PMC article.
Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry.
Chen J, Young SM, Allen C, Seeber A, Péli-Gulli MP, Panchaud N, Waller A, Ursu O, Yao T, Golden JE, Strouse JJ, Carter MB, Kang H, Bologa CG, Foutz TD, Edwards BS, Peterson BR, Aubé J, Werner-Washburne M, Loewith RJ, De Virgilio C, Sklar LA. Chen J, et al. Among authors: ursu o. ACS Chem Biol. 2012 Apr 20;7(4):715-22. doi: 10.1021/cb200452r. Epub 2012 Feb 1. ACS Chem Biol. 2012. PMID: 22260433 Free PMC article.
Characterization of a Cdc42 protein inhibitor and its use as a molecular probe.
Hong L, Kenney SR, Phillips GK, Simpson D, Schroeder CE, Nöth J, Romero E, Swanson S, Waller A, Strouse JJ, Carter M, Chigaev A, Ursu O, Oprea T, Hjelle B, Golden JE, Aubé J, Hudson LG, Buranda T, Sklar LA, Wandinger-Ness A. Hong L, et al. Among authors: ursu o. J Biol Chem. 2013 Mar 22;288(12):8531-8543. doi: 10.1074/jbc.M112.435941. Epub 2013 Feb 4. J Biol Chem. 2013. PMID: 23382385 Free PMC article.
Fluorescent substrates for flow cytometric evaluation of efflux inhibition in ABCB1, ABCC1, and ABCG2 transporters.
Strouse JJ, Ivnitski-Steele I, Waller A, Young SM, Perez D, Evangelisti AM, Ursu O, Bologa CG, Carter MB, Salas VM, Tegos G, Larson RS, Oprea TI, Edwards BS, Sklar LA. Strouse JJ, et al. Among authors: ursu o. Anal Biochem. 2013 Jun 1;437(1):77-87. doi: 10.1016/j.ab.2013.02.018. Epub 2013 Mar 5. Anal Biochem. 2013. PMID: 23470221 Free PMC article.
FRET detection of lymphocyte function-associated antigen-1 conformational extension.
Chigaev A, Smagley Y, Haynes MK, Ursu O, Bologa CG, Halip L, Oprea T, Waller A, Carter MB, Zhang Y, Wang W, Buranda T, Sklar LA. Chigaev A, et al. Among authors: ursu o. Mol Biol Cell. 2015 Jan 1;26(1):43-54. doi: 10.1091/mbc.E14-06-1050. Epub 2014 Nov 5. Mol Biol Cell. 2015. PMID: 25378583 Free PMC article.
75 results