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Pancreatic islets from cyclin-dependent kinase 4/R24C (Cdk4) knockin mice have significantly increased beta cell mass and are physiologically functional, indicating that Cdk4 is a potential target for pancreatic beta cell mass regeneration in Type 1 diabetes.
Marzo N, Mora C, Fabregat ME, Martín J, Usac EF, Franco C, Barbacid M, Gomis R. Marzo N, et al. Among authors: usac ef. Diabetologia. 2004 Apr;47(4):686-94. doi: 10.1007/s00125-004-1372-0. Diabetologia. 2004. PMID: 15298346
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