NAViGaTing the micronome--using multiple microRNA prediction databases to identify signalling pathway-associated microRNAs.
PLoS One. 2011.
PMID: 21364759
Free PMC article.
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using multiple microrna prediction databases to identify signaling pathway associated micrornas
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Using Multiple MicroRNA Prediction Databases to Identify Signalling Pathway-Associated MicroRNAs instead
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Identification of hub genes and potential molecular mechanisms related to radiotherapy sensitivity in rectal cancer based on multiple datasets.
J Transl Med. 2023 Mar 6;21(1):176. doi: 10.1186/s12967-023-04029-2.
J Transl Med. 2023.
PMID: 36879254
Free PMC article.
Based on CIBERSORT algorithm, Genomics of Drug Sensitivity in Cancer (GDSC) database, Gene set variation analysis (GSVA), enrichment analysis (GSEA), nomogram, motif enrichment and non-coding RNA network analyses, the associations between hub genes and immune cell i …
Based on CIBERSORT algorithm, Genomics of Drug Sensitivity in Cancer (GDSC) database, Gene set variation analysis (GSVA), enrichment …
Exploring the role and mechanism of Astragalus membranaceus and radix paeoniae rubra in idiopathic pulmonary fibrosis through network pharmacology and experimental validation.
Sci Rep. 2023 Sep 4;13(1):10110. doi: 10.1038/s41598-023-36944-1.
Sci Rep. 2023.
PMID: 37666859
Free PMC article.
Utilizing network pharmacology analysis, differentially expressed genes (DEGs) associated with IPF were obtained from the GEO database. Targets of AM and RPR were identified using the TCM Systems Pharmacology Database and Analysis Platform and SwissTar …
Utilizing network pharmacology analysis, differentially expressed genes (DEGs) associated with IPF were obtained from the GEO data …
NAViGaTing the micronome--using multiple microRNA prediction databases to identify signalling pathway-associated microRNAs.
PLoS One. 2011 Feb 25;6(2):e17429. doi: 10.1371/journal.pone.0017429.
PLoS One. 2011.
PMID: 21364759
Free PMC article.
Since microRNA binding is sequence-based but possibly structure-specific, work in this area has resulted in multiple databases storing predicted microRNA:target relationships computed using diverse algorithms. We integrate prediction d …
Since microRNA binding is sequence-based but possibly structure-specific, work in this area has resulted in multiple databa …
Peripheral microRNA alteration and pathway signaling after mild traumatic brain injury.
Gen Physiol Biophys. 2021 Nov;40(6):523-539. doi: 10.4149/gpb_2021038.
Gen Physiol Biophys. 2021.
PMID: 34897024
In order to define the signature of peripheral miRNAs signaling associated with mild TBI (mTBI), we performed a comprehensive meta-analysis of miRNA profiles in mTBI patients using multiple curated pathway databases. ...Furthermore, we identi …
In order to define the signature of peripheral miRNAs signaling associated with mild TBI (mTBI), we performed a comprehensive …
Biological function and potential application of PANoptosis-related genes in colorectal carcinogenesis.
Sci Rep. 2024 Sep 5;14(1):20672. doi: 10.1038/s41598-024-71625-7.
Sci Rep. 2024.
PMID: 39237645
Free PMC article.
Functional enrichment of key PRGs was analyzed based on databases, and relationships between key PRGs and the immune microenvironment, immune cell infiltration, chemotherapy drug sensitivity, tumor progression genes, single-cell cellular subgroups, signal transdu …
Functional enrichment of key PRGs was analyzed based on databases, and relationships between key PRGs and the immune microenvironment …
Review of transcriptomic responses to hexavalent chromium exposure in lung cells supports a role of epigenetic mediators in carcinogenesis.
Toxicol Lett. 2019 May 1;305:40-50. doi: 10.1016/j.toxlet.2019.01.011. Epub 2019 Jan 25.
Toxicol Lett. 2019.
PMID: 30690063
Review.
This cross-study comparison identified 372 genes with Cr(VI)-induced expression alterations in multiple studies. Pathway enrichment analyses of the commonly modulated genes demonstrated that pathways involved in cytotoxicity / cell proliferation were highly e …
This cross-study comparison identified 372 genes with Cr(VI)-induced expression alterations in multiple studies. Pathway …
Screening of potential key ferroptosis-related genes in sepsis.
PeerJ. 2022 Sep 13;10:e13983. doi: 10.7717/peerj.13983. eCollection 2022.
PeerJ. 2022.
PMID: 36117534
Free PMC article.
Then, the miRNAs and lncRNAs associated with the key clustering modules were predicted by miRWalk 2.0 and LncBase v.2 respectively. ...Then, a significant clustering module containing eight genes was identified. Among them, the following five genes were close …
Then, the miRNAs and lncRNAs associated with the key clustering modules were predicted by miRWalk 2.0 and LncBase v.2 respecti …
Persistent organic pollutants and plasma microRNAs: A community-based profiling analysis.
Environ Int. 2025 Mar;197:109328. doi: 10.1016/j.envint.2025.109328. Epub 2025 Feb 18.
Environ Int. 2025.
PMID: 39999486
Free article.
We performed pathway enrichment analysis based on 11 experimentally validated and prediction-based databases, and performed tissue specificity analysis. ...Pathway enrichment of the associated miRNAs highlighted chromosome segregation, RNA splic …
We performed pathway enrichment analysis based on 11 experimentally validated and prediction-based databases, and perfo …
Immune-based prognostic biomarkers associated with metastasis of osteosarcoma.
Gen Physiol Biophys. 2023 Jan;42(1):1-12. doi: 10.4149/gpb_2022050.
Gen Physiol Biophys. 2023.
PMID: 36705300
This study aimed to identify immune-based prognostic biomarkers associated with metastasis of osteosarcoma. ...Within these two group genes, 122 common genes involved in osteosarcoma metastasis were identified. These genes were enriched in chemokine activity, …
This study aimed to identify immune-based prognostic biomarkers associated with metastasis of osteosarcoma. ...Within these tw …
Single-cell and transcriptomic analyses reveal the influence of diabetes on ovarian cancer.
BMC Genomics. 2024 Jan 2;25(1):1. doi: 10.1186/s12864-023-09893-2.
BMC Genomics. 2024.
PMID: 38166541
Free PMC article.
Enrichment analysis indicated that these genes are primarily associated with neutrophil degranulation, GDP-dissociation inhibitor activity, and the IL-17 signaling pathway, suggesting their involvement in the regulation of the tumor microenvironment. ...CONCL …
Enrichment analysis indicated that these genes are primarily associated with neutrophil degranulation, GDP-dissociation inhibitor act …
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