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Uterine fibroid polygenic risk score (PRS) associates and predicts risk for uterine fibroid.
Piekos JA, Hellwege JN, Zhang Y, Torstenson ES, Jarvik GP, Dikilitas O, Kullo IJ, Schaid DJ, Crosslin DR, Pendergrass SA, Lee MTM, Roden D, Denny JC, Edwards TL, Velez Edwards DR. Piekos JA, et al. Hum Genet. 2022 Nov;141(11):1739-1748. doi: 10.1007/s00439-022-02442-z. Epub 2022 Feb 28. Hum Genet. 2022. PMID: 35226188 Free PMC article.
Uterine fibroids (UF) are common pelvic tumors in women, heritable, and genome-wide association studies (GWAS) have identified ~ 30 loci associated with increased risk in UF. Using summary statistics from a previously published UF GWAS performed in a n
Uterine fibroids (UF) are common pelvic tumors in women, heritable, and genome-wide association studies (GWAS) have identified
Transethnic and race-stratified genome-wide association study of fibroid characteristics in African American and European American women.
Bray MJ, Wellons MF, Jones SH, Torstenson ES, Edwards TL, Velez Edwards DR. Bray MJ, et al. Fertil Steril. 2018 Sep;110(4):737-745.e34. doi: 10.1016/j.fertnstert.2018.04.035. Fertil Steril. 2018. PMID: 30196971 Free PMC article.
OBJECTIVE: To identify, through genome-wide association studies, genetic loci that associate with differences in fibroid size and number in a population of African American and European American women. ...CONCLUSION(S): This study identified many novel …
OBJECTIVE: To identify, through genome-wide association studies, genetic loci that associate with differences in fib