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Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs.
Jiang J, Zhu Q, Gendron TF, Saberi S, McAlonis-Downes M, Seelman A, Stauffer JE, Jafar-Nejad P, Drenner K, Schulte D, Chun S, Sun S, Ling SC, Myers B, Engelhardt J, Katz M, Baughn M, Platoshyn O, Marsala M, Watt A, Heyser CJ, Ard MC, De Muynck L, Daughrity LM, Swing DA, Tessarollo L, Jung CJ, Delpoux A, Utzschneider DT, Hedrick SM, de Jong PJ, Edbauer D, Van Damme P, Petrucelli L, Shaw CE, Bennett CF, Da Cruz S, Ravits J, Rigo F, Cleveland DW, Lagier-Tourenne C. Jiang J, et al. Among authors: utzschneider dt. Neuron. 2016 May 4;90(3):535-50. doi: 10.1016/j.neuron.2016.04.006. Epub 2016 Apr 21. Neuron. 2016. PMID: 27112497 Free PMC article.
TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection.
Alfei F, Kanev K, Hofmann M, Wu M, Ghoneim HE, Roelli P, Utzschneider DT, von Hoesslin M, Cullen JG, Fan Y, Eisenberg V, Wohlleber D, Steiger K, Merkler D, Delorenzi M, Knolle PA, Cohen CJ, Thimme R, Youngblood B, Zehn D. Alfei F, et al. Among authors: utzschneider dt. Nature. 2019 Jul;571(7764):265-269. doi: 10.1038/s41586-019-1326-9. Epub 2019 Jun 17. Nature. 2019. PMID: 31207605
Editorial: Memory T Cells in Chronic Infections and Tumors.
Hofmann M, Jandus C, Lee LN, Utzschneider DT. Hofmann M, et al. Among authors: utzschneider dt. Front Immunol. 2021 Feb 17;12:656010. doi: 10.3389/fimmu.2021.656010. eCollection 2021. Front Immunol. 2021. PMID: 33679814 Free PMC article. No abstract available.
Immune-surveillance through exhausted effector T-cells.
Zehn D, Utzschneider DT, Thimme R. Zehn D, et al. Among authors: utzschneider dt. Curr Opin Virol. 2016 Feb;16:49-54. doi: 10.1016/j.coviro.2016.01.002. Epub 2016 Jan 29. Curr Opin Virol. 2016. PMID: 26826950 Review.
Precursor exhausted T cells: key to successful immunotherapy?
Kallies A, Zehn D, Utzschneider DT. Kallies A, et al. Among authors: utzschneider dt. Nat Rev Immunol. 2020 Feb;20(2):128-136. doi: 10.1038/s41577-019-0223-7. Epub 2019 Oct 7. Nat Rev Immunol. 2020. PMID: 31591533 Review.
29 results