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1973 1
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58 results

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Page 1
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer.
Wasko UN, Jiang J, Dalton TC, Curiel-Garcia A, Edwards AC, Wang Y, Lee B, Orlen M, Tian S, Stalnecker CA, Drizyte-Miller K, Menard M, Dilly J, Sastra SA, Palermo CF, Hasselluhn MC, Decker-Farrell AR, Chang S, Jiang L, Wei X, Yang YC, Helland C, Courtney H, Gindin Y, Muonio K, Zhao R, Kemp SB, Clendenin C, Sor R, Vostrejs WP, Hibshman PS, Amparo AM, Hennessey C, Rees MG, Ronan MM, Roth JA, Brodbeck J, Tomassoni L, Bakir B, Socci ND, Herring LE, Barker NK, Wang J, Cleary JM, Wolpin BM, Chabot JA, Kluger MD, Manji GA, Tsai KY, Sekulic M, Lagana SM, Califano A, Quintana E, Wang Z, Smith JAM, Holderfield M, Wildes D, Lowe SW, Badgley MA, Aguirre AJ, Vonderheide RH, Stanger BZ, Baslan T, Der CJ, Singh M, Olive KP. Wasko UN, et al. Among authors: chabot ja. Nature. 2024 May;629(8013):927-936. doi: 10.1038/s41586-024-07379-z. Epub 2024 Apr 8. Nature. 2024. PMID: 38588697 Free PMC article.
Tumor-selective effects of active RAS inhibition in pancreatic ductal adenocarcinoma.
Wasko UN, Jiang J, Curiel-Garcia A, Wang Y, Lee B, Orlen M, Drizyte-Miller K, Menard M, Dilly J, Sastra SA, Palermo CF, Dalton T, Hasselluhn MC, Decker-Farrell AR, Chang S, Jiang L, Wei X, Yang YC, Helland C, Courtney H, Gindin Y, Zhao R, Kemp SB, Clendenin C, Sor R, Vostrejs W, Amparo AA, Hibshman PS, Rees MG, Ronan MM, Roth JA, Bakir B, Badgley MA, Chabot JA, Kluger MD, Manji GA, Quintana E, Wang Z, Smith JAM, Holderfield M, Wildes D, Aguirre AJ, Der CJ, Vonderheide RH, Stanger BZ, Singh M, Olive KP. Wasko UN, et al. Among authors: chabot ja. bioRxiv [Preprint]. 2023 Dec 4:2023.12.03.569791. doi: 10.1101/2023.12.03.569791. bioRxiv. 2023. PMID: 38105998 Free PMC article. Preprint.
Laparoscopic radical cholecystectomy.
Gumbs AA, Milone L, Geha R, Delacroix J, Chabot JA. Gumbs AA, et al. Among authors: chabot ja. J Laparoendosc Adv Surg Tech A. 2009 Aug;19(4):519-20. doi: 10.1089/lap.2008.0231. J Laparoendosc Adv Surg Tech A. 2009. PMID: 19215212
For stage pT1a tumors, no further surgery is warranted; however, for pT1b or greater lesions, patients usually undergo port-site excisions and completion of open radical cholecystectomy involving a partial hepatectomy of segments IV and V and a lymphadenectomy of the hepat …
For stage pT1a tumors, no further surgery is warranted; however, for pT1b or greater lesions, patients usually undergo port-site excisions a …
The determination of standard metabolic rate in fishes.
Chabot D, Steffensen JF, Farrell AP. Chabot D, et al. J Fish Biol. 2016 Jan;88(1):81-121. doi: 10.1111/jfb.12845. J Fish Biol. 2016. PMID: 26768973 Review.
The degree of agreement between the methods was related to the c.v. of the observations that were classified into the lowest normal distribution, the c.v. MLND (C.V.MLND ). When this indicator was low (5.4), it was advantageous to use the MLND, otherwise, one …
The degree of agreement between the methods was related to the c.v. of the observations that were classified into the lowest normal d …
Effect of Low Versus High Tidal-Volume Total Liquid Ventilation on Pulmonary Inflammation.
Sage M, See W, Nault S, Morin C, Michalski C, Chabot B, Marouan S, Lavoie PM, Micheau P, Praud JP, Fortin-Pellerin É. Sage M, et al. Among authors: chabot b. Front Physiol. 2020 Jun 18;11:603. doi: 10.3389/fphys.2020.00603. eCollection 2020. Front Physiol. 2020. PMID: 32625110 Free PMC article.
Our objective was to compare lung inflammation between low (L-V(T)) and high (H-V(T)) liquid tidal volume and evaluate impacts on the weaning process. ...All but one lamb were successfully extubated within 2 h post-TLV (72 26 min vs. 63 25 min, p = 0.5) with similar …
Our objective was to compare lung inflammation between low (L-V(T)) and high (H-V(T)) liquid tidal volume and evaluate impacts …
Capmatinib efficacy for METex14 non-small cell lung cancer patients: Results of the IFCT-2104 CAPMATU study.
Ferreira M, Swalduz A, Greillier L, du Rusquec P, Curcio H, Raimbourg J, Toffart AC, Gounant V, Couraud S, De Chabot G, Friard S, Hureaux J, Jeannin G, Odier L, Ricordel C, Wislez M, Descarpentries C, Herbreteau G, Missy P, Morin F, Westeel V, Cortot AB. Ferreira M, et al. Among authors: de chabot g. Lung Cancer. 2024 Oct;196:107934. doi: 10.1016/j.lungcan.2024.107934. Epub 2024 Aug 24. Lung Cancer. 2024. PMID: 39277916 Clinical Trial.
[Alpha-1 antitrypsin deficiency caused by Null mutation].
Perrin J, Aimone-Gastin I, Balduyck M, Mercy M, Filhine-Trésarrieu P, Odou MF, Chaouat A, Chabot F. Perrin J, et al. Among authors: chabot f. Rev Mal Respir. 2016 Sep;33(7):612-7. doi: 10.1016/j.rmr.2015.10.007. Epub 2015 Nov 18. Rev Mal Respir. 2016. PMID: 26604020 French.
The study of the SERPINA1 gene, by PCR-sequence of the II, III, IV and V exons and the flanking intronic sequences, allowed identification of the NullQ0ourem allele in homozygous state. ...
The study of the SERPINA1 gene, by PCR-sequence of the II, III, IV and V exons and the flanking intronic sequences, allowed identific …
Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites.
Marill J, Cresteil T, Lanotte M, Chabot GG. Marill J, et al. Among authors: chabot gg. Mol Pharmacol. 2000 Dec;58(6):1341-8. doi: 10.1124/mol.58.6.1341. Mol Pharmacol. 2000. PMID: 11093772
Kinetic studies identified 3A7 as the most active P450 in the formation of three of the metabolites: for 4-OH-retinoic acid, 3A7 showed a V(max)/K(m) of 127.7, followed by 3A5 (V(max)/K(m) = 25.6), 2C8 (V(max)/K(m) = 24.5), 2C18 (V(max)/K(m) = 15.8), 3 …
Kinetic studies identified 3A7 as the most active P450 in the formation of three of the metabolites: for 4-OH-retinoic acid, 3A7 showed a …
58 results