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Proteasome function and protein biosynthesis.
Vabulas RM. Vabulas RM. Curr Opin Clin Nutr Metab Care. 2007 Jan;10(1):24-31. doi: 10.1097/MCO.0b013e328011645b. Curr Opin Clin Nutr Metab Care. 2007. PMID: 17143051 Review.
Protein folding in the cytoplasm and the heat shock response.
Vabulas RM, Raychaudhuri S, Hayer-Hartl M, Hartl FU. Vabulas RM, et al. Cold Spring Harb Perspect Biol. 2010 Dec;2(12):a004390. doi: 10.1101/cshperspect.a004390. Cold Spring Harb Perspect Biol. 2010. PMID: 21123396 Free PMC article. Review.
Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions.
Olzscha H, Schermann SM, Woerner AC, Pinkert S, Hecht MH, Tartaglia GG, Vendruscolo M, Hayer-Hartl M, Hartl FU, Vabulas RM. Olzscha H, et al. Cell. 2011 Jan 7;144(1):67-78. doi: 10.1016/j.cell.2010.11.050. Cell. 2011. PMID: 21215370
Heat shock proteins as ligands of toll-like receptors.
Vabulas RM, Wagner H, Schild H. Vabulas RM, et al. Curr Top Microbiol Immunol. 2002;270:169-84. doi: 10.1007/978-3-642-59430-4_11. Curr Top Microbiol Immunol. 2002. PMID: 12467251 Review.
Recognition of enzymes lacking bound cofactor by protein quality control.
Martínez-Limón A, Alriquet M, Lang WH, Calloni G, Wittig I, Vabulas RM. Martínez-Limón A, et al. Among authors: vabulas rm. Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):12156-12161. doi: 10.1073/pnas.1611994113. Epub 2016 Oct 12. Proc Natl Acad Sci U S A. 2016. PMID: 27733512 Free PMC article.
Quantitative proteomics reveals that Hsp90 inhibition preferentially targets kinases and the DNA damage response.
Sharma K, Vabulas RM, Macek B, Pinkert S, Cox J, Mann M, Hartl FU. Sharma K, et al. Among authors: vabulas rm. Mol Cell Proteomics. 2012 Mar;11(3):M111.014654. doi: 10.1074/mcp.M111.014654. Epub 2011 Dec 13. Mol Cell Proteomics. 2012. PMID: 22167270 Free PMC article.
The endoplasmic reticulum-resident heat shock protein Gp96 activates dendritic cells via the Toll-like receptor 2/4 pathway.
Vabulas RM, Braedel S, Hilf N, Singh-Jasuja H, Herter S, Ahmad-Nejad P, Kirschning CJ, Da Costa C, Rammensee HG, Wagner H, Schild H. Vabulas RM, et al. J Biol Chem. 2002 Jun 7;277(23):20847-53. doi: 10.1074/jbc.M200425200. Epub 2002 Mar 23. J Biol Chem. 2002. PMID: 11912201
Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells.
Vabulas RM, Ahmad-Nejad P, da Costa C, Miethke T, Kirschning CJ, Häcker H, Wagner H. Vabulas RM, et al. J Biol Chem. 2001 Aug 17;276(33):31332-9. doi: 10.1074/jbc.M103217200. Epub 2001 Jun 11. J Biol Chem. 2001. PMID: 11402040
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