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Tolerance of carprofen in patients with asthma caused by non-steroidal anti-inflammatory drugs.
Bianco S, Robuschi M, Simone P, Vaghi A, Pasargiklian M. Bianco S, et al. Among authors: vaghi a. J Int Med Res. 1985;13(5):294-9. doi: 10.1177/030006058501300509. J Int Med Res. 1985. PMID: 4054430 Clinical Trial.
Eight asthmatics with respiratory intolerance to NSAIDs and two subjects (one asthmatic, one healthy) only sensitive (asthma) to pyrazolone drugs were challenged under single-blind conditions with a new NSAID, carprofen. ...Among the other patients, only three developed co …
Eight asthmatics with respiratory intolerance to NSAIDs and two subjects (one asthmatic, one healthy) only sensitive (asthma) to pyrazolone …
Inhaled transmembrane ion transport modulators and non-steroidal anti-inflammatory drugs in asthma.
Bianco S, Robuschi M, Vaghi A, Fumagalli A, Sestini P. Bianco S, et al. Among authors: vaghi a. Thorax. 2000 Oct;55 Suppl 2(Suppl 2):S48-50. doi: 10.1136/thorax.55.suppl_2.s48. Thorax. 2000. PMID: 10992558 Free PMC article. Review. No abstract available.
Different effects of inhaled aspirinlike drugs on allergen-induced early and late asthmatic responses.
Sestini P, Refini RM, Pieroni MG, Vaghi A, Robuschi M, Bianco S. Sestini P, et al. Among authors: vaghi a. Am J Respir Crit Care Med. 1999 Apr;159(4 Pt 1):1228-33. doi: 10.1164/ajrccm.159.4.9709045. Am J Respir Crit Care Med. 1999. PMID: 10194170 Clinical Trial.
We compared the effects of two aspirin-like drugs with different pharmacologic activities, sodium salicylate (SSA) and indomethacin, with the effect of lysine acetylsalicylate (LASA), inhaled 30 min before challenge, on the early and the late asthmatic response induced by a
We compared the effects of two aspirin-like drugs with different pharmacologic activities, sodium salicylate (SSA) and indomethacin, with th …
Protective effect of inhaled lysine acetylsalicylate on allergen-induced early and late asthmatic reactions.
Sestini P, Refini RM, Pieroni MG, Vaghi A, Robuschi M, Bianco S. Sestini P, et al. Among authors: vaghi a. J Allergy Clin Immunol. 1997 Jul;100(1):71-7. doi: 10.1016/s0091-6749(97)70197-0. J Allergy Clin Immunol. 1997. PMID: 9257790 Clinical Trial.
We studied 16 patients with mild, stable asthma who had an early asthmatic response and 10 patients with a dual (early and late) response. Each patient underwent two challenges with a single dose of allergen assessed in a preliminary test, after inhalation of …
We studied 16 patients with mild, stable asthma who had an early asthmatic response and 10 patients with a dual (early and late) resp …
Attenuation of aspirin-induced bronchoconstriction by sodium cromoglycate and nedocromil sodium.
Robuschi M, Gambaro G, Sestini P, Pieroni MG, Refini RM, Vaghi A, Bianco S. Robuschi M, et al. Among authors: vaghi a. Am J Respir Crit Care Med. 1997 Apr;155(4):1461-4. doi: 10.1164/ajrccm.155.4.9105094. Am J Respir Crit Care Med. 1997. PMID: 9105094 Clinical Trial.
Because it has been reported that aspirin-induced platelet-mediated cytotoxic activity in vitro is inhibited after treatment in vivo with nedocromil but not with cromoglycate, we investigated whether these compounds also exhibit a different protective activity against aspi …
Because it has been reported that aspirin-induced platelet-mediated cytotoxic activity in vitro is inhibited after treatment in vivo with ne …
Inhaled loop diuretics as potential new anti-asthmatic drugs.
Bianco S, Pieroni MG, Refini RM, Robuschi M, Vaghi A, Sestini P. Bianco S, et al. Among authors: vaghi a. Eur Respir J. 1993 Jan;6(1):130-4. Eur Respir J. 1993. PMID: 8425583 Review.
The observations that treatment with a combination of inhaled acetylsalicylate and frusemide results in a markedly increased bronchoprotective effect compared to either drug alone, opens a new perspective in the possible clinical use of these drugs. Prelimina …
The observations that treatment with a combination of inhaled acetylsalicylate and frusemide results in a markedly increased b …
Potentiation of the antireactive, antiasthmatic effect of inhaled furosemide by inhaled lysine acetylsalicylate.
Bianco S, Vaghi A, Pieroni MG, Robuschi M, Refini RM, Berni F, Sestini P. Bianco S, et al. Among authors: vaghi a. Allergy. 1993 Nov;48(8):570-5. doi: 10.1111/j.1398-9995.1993.tb00750.x. Allergy. 1993. PMID: 8116856 Clinical Trial.
Fifteen asthmatic patients underwent bronchial challenge with a mist of ultrasonically nebulized distilled water at the same time of day on four occasions, 2-4 days apart, 15 min after premedication according to a double-blind, randomized protocol. After placebo, me …
Fifteen asthmatic patients underwent bronchial challenge with a mist of ultrasonically nebulized distilled water at the same time of …
Steroid-sparing effect of inhaled lysine acetylsalicylate and furosemide in high-dose beclomethasone-dependent asthma.
Bianco S, Vaghi A, Robuschi M, Refini RM, Pieroni MG, Sestini P. Bianco S, et al. Among authors: vaghi a. J Allergy Clin Immunol. 1995 May;95(5 Pt 1):937-43. doi: 10.1016/s0091-6749(95)70092-7. J Allergy Clin Immunol. 1995. PMID: 7751513 Clinical Trial.
METHODS: We performed a randomized, double-blind, crossover study in nine patients with chronic asthma requiring a high dose (2 mg/day) of inhaled beclomethasone for clinical control. ...The dose of inhaled steroids was reduced by half every 15 days and eventually s …
METHODS: We performed a randomized, double-blind, crossover study in nine patients with chronic asthma requiring a high dose ( …
Protective activity of inhaled nonsteroidal antiinflammatory drugs on bronchial responsiveness to ultrasonically nebulized water.
Bianco S, Vaghi A, Pieroni MG, Robuschi M, Refini RM, Sestini P. Bianco S, et al. Among authors: vaghi a. J Allergy Clin Immunol. 1992 Nov;90(5):833-9. doi: 10.1016/0091-6749(92)90109-f. J Allergy Clin Immunol. 1992. PMID: 1430708 Clinical Trial.
The volume of UNDW causing a 20% fall in FEV1 (UNDW PD20) was calculated by linear interpolation on the dose-response curve. ...Finally, in a third group of asthmatic patients pretreatment with inhaled indomethacin at two dose levels (6 patients, 25 mg; 10 patients, …
The volume of UNDW causing a 20% fall in FEV1 (UNDW PD20) was calculated by linear interpolation on the dose-response curve. ...Final …
Inhaled frusemide is highly effective in preventing ultrasonically nebulised water bronchoconstriction.
Robuschi M, Gambaro G, Spagnotto S, Vaghi A, Bianco S. Robuschi M, et al. Among authors: vaghi a. Pulm Pharmacol. 1989;1(4):187-91. doi: 10.1016/s0952-0600(89)80016-x. Pulm Pharmacol. 1989. PMID: 2520344 Clinical Trial.
A decrease in the osmolarity of the periciliary fluid of central airways is supposed to be the initiating mechanism by which ultrasonically nebulised distilled water (UNH2O) induces bronchoconstriction in asthmatics. ...To test this hypothesis, 16 adult asthmatics were cha
A decrease in the osmolarity of the periciliary fluid of central airways is supposed to be the initiating mechanism by which ultrason
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