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A randomized, double-blind, multicenter, phase 2b study to evaluate the safety and efficacy of a combination of tropifexor and cenicriviroc in patients with nonalcoholic steatohepatitis and liver fibrosis: Study design of the TANDEM trial.
Pedrosa M, Seyedkazemi S, Francque S, Sanyal A, Rinella M, Charlton M, Loomba R, Ratziu V, Kochuparampil J, Fischer L, Vaidyanathan S, Anstee QM. Pedrosa M, et al. Among authors: vaidyanathan s. Contemp Clin Trials. 2020 Jan;88:105889. doi: 10.1016/j.cct.2019.105889. Epub 2019 Nov 13. Contemp Clin Trials. 2020. PMID: 31731005
Clinical pharmacokinetics and pharmacodynamics of aliskiren.
Vaidyanathan S, Jarugula V, Dieterich HA, Howard D, Dole WP. Vaidyanathan S, et al. Clin Pharmacokinet. 2008;47(8):515-31. doi: 10.2165/00003088-200847080-00002. Clin Pharmacokinet. 2008. PMID: 18611061 Review.
Pharmacokinetics of the oral direct renin inhibitor aliskiren in combination with digoxin, atorvastatin, and ketoconazole in healthy subjects: the role of P-glycoprotein in the disposition of aliskiren.
Vaidyanathan S, Camenisch G, Schuetz H, Reynolds C, Yeh CM, Bizot MN, Dieterich HA, Howard D, Dole WP. Vaidyanathan S, et al. J Clin Pharmacol. 2008 Nov;48(11):1323-38. doi: 10.1177/0091270008323258. Epub 2008 Sep 10. J Clin Pharmacol. 2008. PMID: 18784280 Clinical Trial.
Lack of pharmacokinetic interactions of aliskiren, a novel direct renin inhibitor for the treatment of hypertension, with the antihypertensives amlodipine, valsartan, hydrochlorothiazide (HCTZ) and ramipril in healthy volunteers.
Vaidyanathan S, Valencia J, Kemp C, Zhao C, Yeh CM, Bizot MN, Denouel J, Dieterich HA, Dole WP. Vaidyanathan S, et al. Int J Clin Pract. 2006 Nov;60(11):1343-56. doi: 10.1111/j.1742-1241.2006.01164.x. Int J Clin Pract. 2006. PMID: 17073832
531 results