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Strategies for mapping and cloning quantitative trait genes in rodents.
Flint J, Valdar W, Shifman S, Mott R. Flint J, et al. Among authors: valdar w. Nat Rev Genet. 2005 Apr;6(4):271-86. doi: 10.1038/nrg1576. Nat Rev Genet. 2005. PMID: 15803197 Review.
A resource for the simultaneous high-resolution mapping of multiple quantitative trait loci in rats: the NIH heterogeneous stock.
Johannesson M, Lopez-Aumatell R, Stridh P, Diez M, Tuncel J, Blázquez G, Martinez-Membrives E, Cañete T, Vicens-Costa E, Graham D, Copley RR, Hernandez-Pliego P, Beyeen AD, Ockinger J, Fernández-Santamaría C, Gulko PS, Brenner M, Tobeña A, Guitart-Masip M, Giménez-Llort L, Dominiczak A, Holmdahl R, Gauguier D, Olsson T, Mott R, Valdar W, Redei EE, Fernández-Teruel A, Flint J. Johannesson M, et al. Among authors: valdar w. Genome Res. 2009 Jan;19(1):150-8. doi: 10.1101/gr.081497.108. Epub 2008 Oct 29. Genome Res. 2009. PMID: 18971309 Free PMC article.
QTL fine-mapping with recombinant-inbred heterogeneous stocks and in vitro heterogeneous stocks.
Valdar WS, Flint J, Mott R. Valdar WS, et al. Mamm Genome. 2003 Dec;14(12):830-8. doi: 10.1007/s00335-003-3021-1. Mamm Genome. 2003. PMID: 14724734
Estimating the number of coding mutations in genotypic and phenotypic driven N-ethyl-N-nitrosourea (ENU) screens: revisited.
Keays DA, Clark TG, Campbell TG, Broxholme J, Valdar W. Keays DA, et al. Among authors: valdar w. Mamm Genome. 2007 Feb;18(2):123-4. doi: 10.1007/s00335-006-0065-z. Epub 2007 Mar 8. Mamm Genome. 2007. PMID: 17347895
A protocol for high-throughput phenotyping, suitable for quantitative trait analysis in mice.
Solberg LC, Valdar W, Gauguier D, Nunez G, Taylor A, Burnett S, Arboledas-Hita C, Hernandez-Pliego P, Davidson S, Burns P, Bhattacharya S, Hough T, Higgs D, Klenerman P, Cookson WO, Zhang Y, Deacon RM, Rawlins JN, Mott R, Flint J. Solberg LC, et al. Among authors: valdar w. Mamm Genome. 2006 Feb;17(2):129-46. doi: 10.1007/s00335-005-0112-1. Epub 2006 Feb 6. Mamm Genome. 2006. PMID: 16465593
Genome-wide genetic association of complex traits in heterogeneous stock mice.
Valdar W, Solberg LC, Gauguier D, Burnett S, Klenerman P, Cookson WO, Taylor MS, Rawlins JN, Mott R, Flint J. Valdar W, et al. Nat Genet. 2006 Aug;38(8):879-87. doi: 10.1038/ng1840. Epub 2006 Jul 9. Nat Genet. 2006. PMID: 16832355
Analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance.
Crowley JJ, Zhabotynsky V, Sun W, Huang S, Pakatci IK, Kim Y, Wang JR, Morgan AP, Calaway JD, Aylor DL, Yun Z, Bell TA, Buus RJ, Calaway ME, Didion JP, Gooch TJ, Hansen SD, Robinson NN, Shaw GD, Spence JS, Quackenbush CR, Barrick CJ, Nonneman RJ, Kim K, Xenakis J, Xie Y, Valdar W, Lenarcic AB, Wang W, Welsh CE, Fu CP, Zhang Z, Holt J, Guo Z, Threadgill DW, Tarantino LM, Miller DR, Zou F, McMillan L, Sullivan PF, Pardo-Manuel de Villena F. Crowley JJ, et al. Among authors: valdar w. Nat Genet. 2015 Apr;47(4):353-60. doi: 10.1038/ng.3222. Epub 2015 Mar 2. Nat Genet. 2015. PMID: 25730764 Free PMC article.
Genetic Fine-Mapping and Identification of Candidate Genes and Variants for Adiposity Traits in Outbred Rats.
Keele GR, Prokop JW, He H, Holl K, Littrell J, Deal A, Francic S, Cui L, Gatti DM, Broman KW, Tschannen M, Tsaih SW, Zagloul M, Kim Y, Baur B, Fox J, Robinson M, Levy S, Flister MJ, Mott R, Valdar W, Solberg Woods LC. Keele GR, et al. Among authors: valdar w. Obesity (Silver Spring). 2018 Jan;26(1):213-222. doi: 10.1002/oby.22075. Epub 2017 Nov 28. Obesity (Silver Spring). 2018. PMID: 29193816 Free PMC article.
Deciphering gene-environment interactions through mouse models of allergic asthma.
Willis-Owen SA, Valdar W. Willis-Owen SA, et al. Among authors: valdar w. J Allergy Clin Immunol. 2009 Jan;123(1):14-23; quiz 24-5. doi: 10.1016/j.jaci.2008.09.016. Epub 2008 Oct 16. J Allergy Clin Immunol. 2009. PMID: 18926561
High resolution mapping of expression QTLs in heterogeneous stock mice in multiple tissues.
Huang GJ, Shifman S, Valdar W, Johannesson M, Yalcin B, Taylor MS, Taylor JM, Mott R, Flint J. Huang GJ, et al. Among authors: valdar w. Genome Res. 2009 Jun;19(6):1133-40. doi: 10.1101/gr.088120.108. Epub 2009 Apr 17. Genome Res. 2009. PMID: 19376938 Free PMC article.
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