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The lysosomal proteome of senescent cells contributes to the senescence secretome.
Rovira M, Sereda R, Pladevall-Morera D, Ramponi V, Marin I, Maus M, Madrigal-Matute J, Díaz A, García F, Muñoz J, Cuervo AM, Serrano M. Rovira M, et al. Among authors: ramponi v. Aging Cell. 2022 Oct;21(10):e13707. doi: 10.1111/acel.13707. Epub 2022 Sep 10. Aging Cell. 2022. PMID: 36087066 Free PMC article.
Human senescent fibroblasts trigger progressive lung fibrosis in mice.
Hernandez-Gonzalez F, Prats N, Ramponi V, López-Domínguez JA, Meyer K, Aguilera M, Muñoz Martín MI, Martínez D, Agusti A, Faner R, Sellarés J, Pietrocola F, Serrano M. Hernandez-Gonzalez F, et al. Among authors: ramponi v. Aging (Albany NY). 2023 Jul 1;15(14):6641-6657. doi: 10.18632/aging.204825. Epub 2023 Jul 1. Aging (Albany NY). 2023. PMID: 37393107 Free PMC article.
A combination of PARP and CHK1 inhibitors efficiently antagonizes MYCN-driven tumors.
Di Giulio S, Colicchia V, Pastorino F, Pedretti F, Fabretti F, Nicolis di Robilant V, Ramponi V, Scafetta G, Moretti M, Licursi V, Belardinilli F, Peruzzi G, Infante P, Goffredo BM, Coppa A, Canettieri G, Bartolazzi A, Ponzoni M, Giannini G, Petroni M. Di Giulio S, et al. Among authors: ramponi v. Oncogene. 2021 Oct;40(43):6143-6152. doi: 10.1038/s41388-021-02003-0. Epub 2021 Sep 10. Oncogene. 2021. PMID: 34508175 Free PMC article.
SMO-M2 mutation does not support cell-autonomous Hedgehog activity in cerebellar granule cell precursors.
Petroni M, Sahùn Roncero M, Ramponi V, Fabretti F, Nicolis Di Robilant V, Moretti M, Alfano V, Corsi A, De Panfilis S, Giubettini M, Di Giulio S, Capalbo C, Belardinilli F, Coppa A, Sardina F, Colicchia V, Pedretti F, Infante P, Cardinali B, Tessitore A, Canettieri G, De Smaele E, Giannini G. Petroni M, et al. Among authors: ramponi v. Sci Rep. 2019 Dec 23;9(1):19623. doi: 10.1038/s41598-019-56057-y. Sci Rep. 2019. PMID: 31873117 Free PMC article.