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Radiation-induced release of transforming growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced cell death.
Dent P, Reardon DB, Park JS, Bowers G, Logsdon C, Valerie K, Schmidt-Ullrich R. Dent P, et al. Among authors: valerie k. Mol Biol Cell. 1999 Aug;10(8):2493-506. doi: 10.1091/mbc.10.8.2493. Mol Biol Cell. 1999. PMID: 10436007 Free PMC article.
Ionizing radiation stimulates existing signal transduction pathways involving the activation of epidermal growth factor receptor and ERBB-3, and changes of intracellular calcium in A431 human squamous carcinoma cells.
Todd DG, Mikkelsen RB, Rorrer WK, Valerie K, Schmidt-Ullrich RK. Todd DG, et al. Among authors: valerie k. J Recept Signal Transduct Res. 1999 Nov;19(6):885-908. doi: 10.3109/10799899909038430. J Recept Signal Transduct Res. 1999. PMID: 10533979
156 results