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Recent genetic studies of mouse kidney development.
Yu J, McMahon AP, Valerius MT. Yu J, et al. Among authors: valerius mt. Curr Opin Genet Dev. 2004 Oct;14(5):550-7. doi: 10.1016/j.gde.2004.07.009. Curr Opin Genet Dev. 2004. PMID: 15380247 Review.
Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids.
Freedman BS, Brooks CR, Lam AQ, Fu H, Morizane R, Agrawal V, Saad AF, Li MK, Hughes MR, Werff RV, Peters DT, Lu J, Baccei A, Siedlecki AM, Valerius MT, Musunuru K, McNagny KM, Steinman TI, Zhou J, Lerou PH, Bonventre JV. Freedman BS, et al. Among authors: valerius mt. Nat Commun. 2015 Oct 23;6:8715. doi: 10.1038/ncomms9715. Nat Commun. 2015. PMID: 26493500 Free PMC article.
(Re)Building a Kidney.
Oxburgh L, Carroll TJ, Cleaver O, Gossett DR, Hoshizaki DK, Hubbell JA, Humphreys BD, Jain S, Jensen J, Kaplan DL, Kesselman C, Ketchum CJ, Little MH, McMahon AP, Shankland SJ, Spence JR, Valerius MT, Wertheim JA, Wessely O, Zheng Y, Drummond IA. Oxburgh L, et al. Among authors: valerius mt. J Am Soc Nephrol. 2017 May;28(5):1370-1378. doi: 10.1681/ASN.2016101077. Epub 2017 Jan 17. J Am Soc Nephrol. 2017. PMID: 28096308 Free PMC article.
Disparate levels of beta-catenin activity determine nephron progenitor cell fate.
Ramalingam H, Fessler AR, Das A, Valerius MT, Basta J, Robbins L, Brown AC, Oxburgh L, McMahon AP, Rauchman M, Carroll TJ. Ramalingam H, et al. Among authors: valerius mt. Dev Biol. 2018 Aug 1;440(1):13-21. doi: 10.1016/j.ydbio.2018.04.020. Epub 2018 Apr 26. Dev Biol. 2018. PMID: 29705331 Free PMC article.
Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis.
Humphreys BD, Lin SL, Kobayashi A, Hudson TE, Nowlin BT, Bonventre JV, Valerius MT, McMahon AP, Duffield JS. Humphreys BD, et al. Among authors: valerius mt. Am J Pathol. 2010 Jan;176(1):85-97. doi: 10.2353/ajpath.2010.090517. Epub 2009 Dec 11. Am J Pathol. 2010. PMID: 20008127 Free PMC article.
Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development.
Kobayashi A, Valerius MT, Mugford JW, Carroll TJ, Self M, Oliver G, McMahon AP. Kobayashi A, et al. Among authors: valerius mt. Cell Stem Cell. 2008 Aug 7;3(2):169-81. doi: 10.1016/j.stem.2008.05.020. Cell Stem Cell. 2008. PMID: 18682239 Free PMC article.
Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development.
Naiman N, Fujioka K, Fujino M, Valerius MT, Potter SS, McMahon AP, Kobayashi A. Naiman N, et al. Among authors: valerius mt. Dev Cell. 2017 May 22;41(4):349-365.e3. doi: 10.1016/j.devcel.2017.04.022. Dev Cell. 2017. PMID: 28535371 Free PMC article.
Atlas of gene expression in the developing kidney at microanatomic resolution.
Brunskill EW, Aronow BJ, Georgas K, Rumballe B, Valerius MT, Aronow J, Kaimal V, Jegga AG, Yu J, Grimmond S, McMahon AP, Patterson LT, Little MH, Potter SS. Brunskill EW, et al. Among authors: valerius mt. Dev Cell. 2008 Nov;15(5):781-91. doi: 10.1016/j.devcel.2008.09.007. Dev Cell. 2008. PMID: 19000842 Free PMC article.
Transcriptional profiling of Wnt4 mutant mouse kidneys identifies genes expressed during nephron formation.
Valerius MT, McMahon AP. Valerius MT, et al. Gene Expr Patterns. 2008 May;8(5):297-306. doi: 10.1016/j.gep.2008.02.001. Epub 2008 Feb 9. Gene Expr Patterns. 2008. PMID: 18346943 Free PMC article.
Identification of molecular compartments and genetic circuitry in the developing mammalian kidney.
Yu J, Valerius MT, Duah M, Staser K, Hansard JK, Guo JJ, McMahon J, Vaughan J, Faria D, Georgas K, Rumballe B, Ren Q, Krautzberger AM, Junker JP, Thiagarajan RD, Machanick P, Gray PA, van Oudenaarden A, Rowitch DH, Stiles CD, Ma Q, Grimmond SM, Bailey TL, Little MH, McMahon AP. Yu J, et al. Among authors: valerius mt. Development. 2012 May;139(10):1863-73. doi: 10.1242/dev.074005. Development. 2012. PMID: 22510988 Free PMC article.
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