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Proteolytically processed soluble tumor endothelial marker (TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans.
Vallon M, Essler M. Vallon M, et al. J Biol Chem. 2006 Nov 10;281(45):34179-88. doi: 10.1074/jbc.M605291200. Epub 2006 Sep 17. J Biol Chem. 2006. PMID: 16982628
Cellular recognition of tri-/di-palmitoylated peptides is independent from a domain encompassing the N-terminal seven leucine-rich repeat (LRR)/LRR-like motifs of TLR2.
Meng G, Grabiec A, Vallon M, Ebe B, Hampel S, Bessler W, Wagner H, Kirschning CJ. Meng G, et al. J Biol Chem. 2003 Oct 10;278(41):39822-9. doi: 10.1074/jbc.M304766200. Epub 2003 Jul 14. J Biol Chem. 2003. PMID: 12860988
Tumor endothelial marker 5 expression in endothelial cells during capillary morphogenesis is induced by the small GTPase Rac and mediates contact inhibition of cell proliferation.
Vallon M, Rohde F, Janssen KP, Essler M. Vallon M, et al. Exp Cell Res. 2010 Feb 1;316(3):412-21. doi: 10.1016/j.yexcr.2009.10.013. Epub 2009 Oct 21. Exp Cell Res. 2010. PMID: 19853600
Enhanced efficacy of combined 213Bi-DTPA-F3 and paclitaxel therapy of peritoneal carcinomatosis is mediated by enhanced induction of apoptosis and G2/M phase arrest.
Vallon M, Seidl C, Blechert B, Li Z, Gilbertz KP, Baumgart A, Aichler M, Feuchtinger A, Gaertner FC, Bruchertseifer F, Morgenstern A, Walch AK, Senekowitsch-Schmidtke R, Essler M. Vallon M, et al. Eur J Nucl Med Mol Imaging. 2012 Dec;39(12):1886-97. doi: 10.1007/s00259-012-2203-z. Epub 2012 Aug 8. Eur J Nucl Med Mol Imaging. 2012. PMID: 22872310
RESULTS: Treatment of OVCAR-3 cells in vitro with combined (213)Bi-DTPA-F3 and paclitaxel resulted in enhanced cytotoxicity, induction of apoptosis and G2/M phase arrest compared to treatment with either (213)Bi-DTPA-F3 or paclitaxel. ...
RESULTS: Treatment of OVCAR-3 cells in vitro with combined (213)Bi-DTPA-F3 and paclitaxel resulted in enhanced cytotoxicity, induction of ap …
α-Radioimmunotherapy with ²¹³Bi-anti-CD38 immunoconjugates is effective in a mouse model of human multiple myeloma.
Teiluf K, Seidl C, Blechert B, Gaertner FC, Gilbertz KP, Fernandez V, Bassermann F, Endell J, Boxhammer R, Leclair S, Vallon M, Aichler M, Feuchtinger A, Bruchertseifer F, Morgenstern A, Essler M. Teiluf K, et al. Oncotarget. 2015 Mar 10;6(7):4692-703. doi: 10.18632/oncotarget.2986. Oncotarget. 2015. PMID: 25576914 Free PMC article.
Treatment of peritoneal carcinomatosis by targeted delivery of the radio-labeled tumor homing peptide bi-DTPA-[F3]2 into the nucleus of tumor cells.
Drecoll E, Gaertner FC, Miederer M, Blechert B, Vallon M, Müller JM, Alke A, Seidl C, Bruchertseifer F, Morgenstern A, Senekowitsch-Schmidtke R, Essler M. Drecoll E, et al. PLoS One. 2009 May 27;4(5):e5715. doi: 10.1371/journal.pone.0005715. PLoS One. 2009. PMID: 19479088 Free PMC article.
International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.
Hamann J, Aust G, Araç D, Engel FB, Formstone C, Fredriksson R, Hall RA, Harty BL, Kirchhoff C, Knapp B, Krishnan A, Liebscher I, Lin HH, Martinelli DC, Monk KR, Peeters MC, Piao X, Prömel S, Schöneberg T, Schwartz TW, Singer K, Stacey M, Ushkaryov YA, Vallon M, Wolfrum U, Wright MW, Xu L, Langenhan T, Schiöth HB. Hamann J, et al. Among authors: vallon m. Pharmacol Rev. 2015;67(2):338-67. doi: 10.1124/pr.114.009647. Pharmacol Rev. 2015. PMID: 25713288 Free PMC article. Review.
The expanding functional roles and signaling mechanisms of adhesion G protein-coupled receptors.
Morgan RK, Anderson GR, Araç D, Aust G, Balenga N, Boucard A, Bridges JP, Engel FB, Formstone CJ, Glitsch MD, Gray RS, Hall RA, Hsiao CC, Kim HY, Knierim AB, Kusuluri DK, Leon K, Liebscher I, Piao X, Prömel S, Scholz N, Srivastava S, Thor D, Tolias KF, Ushkaryov YA, Vallon M, Van Meir EG, Vanhollebeke B, Wolfrum U, Wright KM, Monk KR, Mogha A. Morgan RK, et al. Among authors: vallon m. Ann N Y Acad Sci. 2019 Nov;1456(1):5-25. doi: 10.1111/nyas.14094. Epub 2019 Jun 6. Ann N Y Acad Sci. 2019. PMID: 31168816
A RECK-WNT7 Receptor-Ligand Interaction Enables Isoform-Specific Regulation of Wnt Bioavailability.
Vallon M, Yuki K, Nguyen TD, Chang J, Yuan J, Siepe D, Miao Y, Essler M, Noda M, Garcia KC, Kuo CJ. Vallon M, et al. Cell Rep. 2018 Oct 9;25(2):339-349.e9. doi: 10.1016/j.celrep.2018.09.045. Cell Rep. 2018. PMID: 30304675 Free PMC article.
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