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Glycosylation pattern of mature dimeric leukocyte and recombinant monomeric myeloperoxidase: glycosylation is required for optimal enzymatic activity.
Van Antwerpen P, Slomianny MC, Boudjeltia KZ, Delporte C, Faid V, Calay D, Rousseau A, Moguilevsky N, Raes M, Vanhamme L, Furtmüller PG, Obinger C, Vanhaeverbeek M, Nève J, Michalski JC. Van Antwerpen P, et al. J Biol Chem. 2010 May 21;285(21):16351-9. doi: 10.1074/jbc.M109.089748. Epub 2010 Mar 23. J Biol Chem. 2010. PMID: 20332087 Free PMC article.
Optimization of apolipoprotein-B-100 sequence coverage by liquid chromatography-tandem mass spectrometry for the future study of its posttranslational modifications.
Delporte C, Van Antwerpen P, Zouaoui Boudjeltia K, Noyon C, Abts F, Métral F, Vanhamme L, Reyé F, Rousseau A, Vanhaeverbeek M, Ducobu J, Nève J. Delporte C, et al. Among authors: van antwerpen p. Anal Biochem. 2011 Apr 1;411(1):129-38. doi: 10.1016/j.ab.2010.11.039. Epub 2010 Dec 1. Anal Biochem. 2011. PMID: 21129357
Impact of myeloperoxidase-LDL interactions on enzyme activity and subsequent posttranslational oxidative modifications of apoB-100.
Delporte C, Boudjeltia KZ, Noyon C, Furtmüller PG, Nuyens V, Slomianny MC, Madhoun P, Desmet JM, Raynal P, Dufour D, Koyani CN, Reyé F, Rousseau A, Vanhaeverbeek M, Ducobu J, Michalski JC, Nève J, Vanhamme L, Obinger C, Malle E, Van Antwerpen P. Delporte C, et al. Among authors: van antwerpen p. J Lipid Res. 2014 Apr;55(4):747-57. doi: 10.1194/jlr.M047449. Epub 2014 Feb 17. J Lipid Res. 2014. PMID: 24534704 Free PMC article.
LC-MS analysis combined with principal component analysis and soft independent modelling by class analogy for a better detection of changes in N-glycosylation profiles of therapeutic glycoproteins.
Planinc A, Dejaegher B, Heyden YV, Viaene J, Van Praet S, Rappez F, Van Antwerpen P, Delporte C. Planinc A, et al. Among authors: van praet s, van antwerpen p. Anal Bioanal Chem. 2017 Jan;409(2):477-485. doi: 10.1007/s00216-016-9683-9. Epub 2016 Jun 10. Anal Bioanal Chem. 2017. PMID: 27287011
Rational drug design applied to myeloperoxidase inhibition.
Van Antwerpen P, Zouaoui Boudjeltia K. Van Antwerpen P, et al. Free Radic Res. 2015 Jun;49(6):711-20. doi: 10.3109/10715762.2015.1027201. Epub 2015 Apr 24. Free Radic Res. 2015. PMID: 25788127 Review.
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