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Dendritic cell vaccination as postremission treatment to prevent or delay relapse in acute myeloid leukemia.
Anguille S, Van de Velde AL, Smits EL, Van Tendeloo VF, Juliusson G, Cools N, Nijs G, Stein B, Lion E, Van Driessche A, Vandenbosch I, Verlinden A, Gadisseur AP, Schroyens WA, Muylle L, Vermeulen K, Maes MB, Deiteren K, Malfait R, Gostick E, Lammens M, Couttenye MM, Jorens P, Goossens H, Price DA, Ladell K, Oka Y, Fujiki F, Oji Y, Sugiyama H, Berneman ZN. Anguille S, et al. Among authors: van driessche a. Blood. 2017 Oct 12;130(15):1713-1721. doi: 10.1182/blood-2017-04-780155. Epub 2017 Aug 22. Blood. 2017. PMID: 28830889 Free PMC article. Clinical Trial.
Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccination.
Van Tendeloo VF, Van de Velde A, Van Driessche A, Cools N, Anguille S, Ladell K, Gostick E, Vermeulen K, Pieters K, Nijs G, Stein B, Smits EL, Schroyens WA, Gadisseur AP, Vrelust I, Jorens PG, Goossens H, de Vries IJ, Price DA, Oji Y, Oka Y, Sugiyama H, Berneman ZN. Van Tendeloo VF, et al. Among authors: van driessche a, van de velde a. Proc Natl Acad Sci U S A. 2010 Aug 3;107(31):13824-9. doi: 10.1073/pnas.1008051107. Epub 2010 Jul 14. Proc Natl Acad Sci U S A. 2010. PMID: 20631300 Free PMC article. Clinical Trial.
Messenger RNA electroporation of human monocytes, followed by rapid in vitro differentiation, leads to highly stimulatory antigen-loaded mature dendritic cells.
Ponsaerts P, Van den Bosch G, Cools N, Van Driessche A, Nijs G, Lenjou M, Lardon F, Van Broeckhoven C, Van Bockstaele DR, Berneman ZN, Van Tendeloo VF. Ponsaerts P, et al. Among authors: van tendeloo vf, van driessche a, van den bosch g, van broeckhoven c, van bockstaele dr. J Immunol. 2002 Aug 15;169(4):1669-75. doi: 10.4049/jimmunol.169.4.1669. J Immunol. 2002. PMID: 12165485
Clinical-grade manufacturing of autologous mature mRNA-electroporated dendritic cells and safety testing in acute myeloid leukemia patients in a phase I dose-escalation clinical trial.
Van Driessche A, Van de Velde AL, Nijs G, Braeckman T, Stein B, De Vries JM, Berneman ZN, Van Tendeloo VF. Van Driessche A, et al. Among authors: van tendeloo vf, van de velde al. Cytotherapy. 2009;11(5):653-68. doi: 10.1080/14653240902960411. Cytotherapy. 2009. PMID: 19530029 Clinical Trial.
Antigen-specific cellular immunotherapy of leukemia.
Van Driessche A, Gao L, Stauss HJ, Ponsaerts P, Van Bockstaele DR, Berneman ZN, Van Tendeloo VF. Van Driessche A, et al. Among authors: van tendeloo vf, van bockstaele dr. Leukemia. 2005 Nov;19(11):1863-71. doi: 10.1038/sj.leu.2403930. Leukemia. 2005. PMID: 16121214 Review.
mRNA-electroporated mature dendritic cells retain transgene expression, phenotypical properties and stimulatory capacity after cryopreservation.
Ponsaerts P, Van Tendeloo VF, Cools N, Van Driessche A, Lardon F, Nijs G, Lenjou M, Mertens G, Van Broeckhoven C, Van Bockstaele DR, Berneman ZN. Ponsaerts P, et al. Among authors: van tendeloo vf, van driessche a, van broeckhoven c, van bockstaele dr. Leukemia. 2002 Jul;16(7):1324-30. doi: 10.1038/sj.leu.2402511. Leukemia. 2002. PMID: 12094257
Proinflammatory response of human leukemic cells to dsRNA transfection linked to activation of dendritic cells.
Smits EL, Ponsaerts P, Van de Velde AL, Van Driessche A, Cools N, Lenjou M, Nijs G, Van Bockstaele DR, Berneman ZN, Van Tendeloo VF. Smits EL, et al. Among authors: van tendeloo vf, van driessche a, van de velde al, van bockstaele dr. Leukemia. 2007 Aug;21(8):1691-9. doi: 10.1038/sj.leu.2404763. Epub 2007 May 24. Leukemia. 2007. PMID: 17525722
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