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SHP2 is required for BCR-ABL1-induced hematologic neoplasia.
Gu S, Sayad A, Chan G, Yang W, Lu Z, Virtanen C, Van Etten RA, Neel BG. Gu S, et al. Among authors: van etten ra. Leukemia. 2018 Jan;32(1):203-213. doi: 10.1038/leu.2017.250. Epub 2017 Aug 14. Leukemia. 2018. PMID: 28804122 Free PMC article.
Critical role for Gab2 in transformation by BCR/ABL.
Sattler M, Mohi MG, Pride YB, Quinnan LR, Malouf NA, Podar K, Gesbert F, Iwasaki H, Li S, Van Etten RA, Gu H, Griffin JD, Neel BG. Sattler M, et al. Among authors: van etten ra. Cancer Cell. 2002 Jun;1(5):479-92. doi: 10.1016/s1535-6108(02)00074-0. Cancer Cell. 2002. PMID: 12124177 Free article.
Specific, targetable interactions with the microenvironment influence imatinib-resistant chronic myeloid leukemia.
Kumar R, Pereira RS, Zanetti C, Minciacchi VR, Merten M, Meister M, Niemann J, Dietz MS, Rüssel N, Schnütgen F, Tamai M, Akahane K, Inukai T, Oellerich T, Kvasnicka HM, Pfeifer H, Nicolini FE, Heilemann M, Van Etten RA, Krause DS. Kumar R, et al. Among authors: van etten ra. Leukemia. 2020 Aug;34(8):2087-2101. doi: 10.1038/s41375-020-0866-1. Epub 2020 May 21. Leukemia. 2020. PMID: 32439895 Free PMC article.
Recent advances in the genomics and therapy of BCR/ABL1-positive and -negative chronic myeloproliferative neoplasms.
Mughal TI, Gotlib J, Mesa R, Koschmieder S, Khoury HJ, Cortes JE, Barbui T, Hehlmann R, Mauro M, Saussele S, Radich JP, Van Etten RA, Saglio G, Verstovek S, Gale RP, Abdel-Wahab O. Mughal TI, et al. Among authors: van etten ra. Leuk Res. 2018 Apr;67:67-74. doi: 10.1016/j.leukres.2018.02.008. Epub 2018 Feb 14. Leuk Res. 2018. PMID: 29466766 Free PMC article. Review.
Conformational control inhibition of the BCR-ABL1 tyrosine kinase, including the gatekeeper T315I mutant, by the switch-control inhibitor DCC-2036.
Chan WW, Wise SC, Kaufman MD, Ahn YM, Ensinger CL, Haack T, Hood MM, Jones J, Lord JW, Lu WP, Miller D, Patt WC, Smith BD, Petillo PA, Rutkoski TJ, Telikepalli H, Vogeti L, Yao T, Chun L, Clark R, Evangelista P, Gavrilescu LC, Lazarides K, Zaleskas VM, Stewart LJ, Van Etten RA, Flynn DL. Chan WW, et al. Among authors: van etten ra. Cancer Cell. 2011 Apr 12;19(4):556-68. doi: 10.1016/j.ccr.2011.03.003. Cancer Cell. 2011. PMID: 21481795 Free PMC article.
129 results