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RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome.
Duprez L, Takahashi N, Van Hauwermeiren F, Vandendriessche B, Goossens V, Vanden Berghe T, Declercq W, Libert C, Cauwels A, Vandenabeele P. Duprez L, et al. Among authors: van hauwermeiren f. Immunity. 2011 Dec 23;35(6):908-18. doi: 10.1016/j.immuni.2011.09.020. Immunity. 2011. PMID: 22195746 Free article.
Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models.
Takahashi N, Duprez L, Grootjans S, Cauwels A, Nerinckx W, DuHadaway JB, Goossens V, Roelandt R, Van Hauwermeiren F, Libert C, Declercq W, Callewaert N, Prendergast GC, Degterev A, Yuan J, Vandenabeele P. Takahashi N, et al. Among authors: van hauwermeiren f. Cell Death Dis. 2012 Nov 29;3(11):e437. doi: 10.1038/cddis.2012.176. Cell Death Dis. 2012. PMID: 23190609 Free PMC article.
Type I interferon drives tumor necrosis factor-induced lethal shock.
Huys L, Van Hauwermeiren F, Dejager L, Dejonckheere E, Lienenklaus S, Weiss S, Leclercq G, Libert C. Huys L, et al. Among authors: van hauwermeiren f. J Exp Med. 2009 Aug 31;206(9):1873-82. doi: 10.1084/jem.20090213. Epub 2009 Aug 17. J Exp Med. 2009. PMID: 19687227 Free PMC article.
Regulation and dysregulation of tumor necrosis factor receptor-1.
Puimège L, Libert C, Van Hauwermeiren F. Puimège L, et al. Among authors: van hauwermeiren f. Cytokine Growth Factor Rev. 2014 Jun;25(3):285-300. doi: 10.1016/j.cytogfr.2014.03.004. Epub 2014 Mar 24. Cytokine Growth Factor Rev. 2014. PMID: 24746195 Review.
TNFR1-induced lethal inflammation is mediated by goblet and Paneth cell dysfunction.
Van Hauwermeiren F, Vandenbroucke RE, Grine L, Lodens S, Van Wonterghem E, De Rycke R, De Geest N, Hassan B, Libert C. Van Hauwermeiren F, et al. Among authors: van wonterghem e. Mucosal Immunol. 2015 Jul;8(4):828-40. doi: 10.1038/mi.2014.112. Epub 2014 Nov 26. Mucosal Immunol. 2015. PMID: 25425265 Free article.
Matrix metalloprotease 8-dependent extracellular matrix cleavage at the blood-CSF barrier contributes to lethality during systemic inflammatory diseases.
Vandenbroucke RE, Dejonckheere E, Van Lint P, Demeestere D, Van Wonterghem E, Vanlaere I, Puimège L, Van Hauwermeiren F, De Rycke R, Mc Guire C, Campestre C, López-Otin C, Matthys P, Leclercq G, Libert C. Vandenbroucke RE, et al. Among authors: van wonterghem e, van hauwermeiren f, van lint p. J Neurosci. 2012 Jul 18;32(29):9805-16. doi: 10.1523/JNEUROSCI.0967-12.2012. J Neurosci. 2012. PMID: 22815495 Free PMC article.
Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium.
Van Hauwermeiren F, Armaka M, Karagianni N, Kranidioti K, Vandenbroucke RE, Loges S, Van Roy M, Staelens J, Puimège L, Palagani A, Berghe WV, Victoratos P, Carmeliet P, Libert C, Kollias G. Van Hauwermeiren F, et al. Among authors: van roy m. J Clin Invest. 2013 Jun;123(6):2590-603. doi: 10.1172/JCI65624. Epub 2013 May 15. J Clin Invest. 2013. PMID: 23676465 Free PMC article.
Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF.
Vandenbroucke RE, Dejonckheere E, Van Hauwermeiren F, Lodens S, De Rycke R, Van Wonterghem E, Staes A, Gevaert K, López-Otin C, Libert C. Vandenbroucke RE, et al. Among authors: van wonterghem e, van hauwermeiren f. EMBO Mol Med. 2013 Jul;5(7):1000-16. doi: 10.1002/emmm.201202100. Epub 2013 May 30. EMBO Mol Med. 2013. PMID: 23723167 Free PMC article.
33 results