Van Hoecke L - Search Results

1

Bronchoalveolar Lavage of Murine Lungs to Analyze Inflammatory Cell Infiltration.

Van Hoecke L, Job ER, Saelens X, Roose K. Van Hoecke L, et al. J Vis Exp. 2017 May 4;(123):55398. doi: 10.3791/55398. J Vis Exp. 2017. PMID: 28518083 Free PMC article.

2

GM-CSF treatment prevents respiratory syncytial virus-induced pulmonary exacerbation responses in postallergic mice by stimulating alveolar macrophage maturation.

Naessens T, Schepens B, Smet M, Pollard C, Van Hoecke L, De Beuckelaer A, Willart M, Lambrecht B, De Koker S, Saelens X, Grooten J. Naessens T, et al. Among authors: van hoecke l. J Allergy Clin Immunol. 2016 Mar;137(3):700-9.e9. doi: 10.1016/j.jaci.2015.09.031. Epub 2015 Nov 10. J Allergy Clin Immunol. 2016. PMID: 26560044

3

Type I Interferons Interfere with the Capacity of mRNA Lipoplex Vaccines to Elicit Cytolytic T Cell Responses.

De Beuckelaer A, Pollard C, Van Lint S, Roose K, Van Hoecke L, Naessens T, Udhayakumar VK, Smet M, Sanders N, Lienenklaus S, Saelens X, Weiss S, Vanham G, Grooten J, De Koker S. De Beuckelaer A, et al. Among authors: van lint s, van hoecke l. Mol Ther. 2016 Nov;24(11):2012-2020. doi: 10.1038/mt.2016.161. Epub 2016 Aug 10. Mol Ther. 2016. PMID: 27506450 Free PMC article.

4

Chemical-controlled Activation of Antiviral Myxovirus Resistance Protein 1.

Verhelst J, Van Hoecke L, Spitaels J, De Vlieger D, Kolpe A, Saelens X. Verhelst J, et al. Among authors: van hoecke l. J Biol Chem. 2017 Feb 10;292(6):2226-2236. doi: 10.1074/jbc.M116.748806. Epub 2016 Dec 23. J Biol Chem. 2017. PMID: 28011636 Free PMC article.

5

Arginine-Rich Peptide-Based mRNA Nanocomplexes Efficiently Instigate Cytotoxic T Cell Immunity Dependent on the Amphipathic Organization of the Peptide.

Udhayakumar VK, De Beuckelaer A, McCaffrey J, McCrudden CM, Kirschman JL, Vanover D, Van Hoecke L, Roose K, Deswarte K, De Geest BG, Lienenklaus S, Santangelo PJ, Grooten J, McCarthy HO, De Koker S. Udhayakumar VK, et al. Among authors: van hoecke l. Adv Healthc Mater. 2017 Jul;6(13). doi: 10.1002/adhm.201601412. Epub 2017 Apr 24. Adv Healthc Mater. 2017. PMID: 28436620

6

Inflammatory monocytes regulate Th1 oriented immunity to CpG adjuvanted protein vaccines through production of IL-12.

De Koker S, Van Hoecke L, De Beuckelaer A, Roose K, Deswarte K, Willart MA, Bogaert P, Naessens T, De Geest BG, Saelens X, Lambrecht BN, Grooten J. De Koker S, et al. Among authors: van hoecke l. Sci Rep. 2017 Jul 20;7(1):5986. doi: 10.1038/s41598-017-06236-6. Sci Rep. 2017. PMID: 28729715 Free PMC article.

7

Transiently Thermoresponsive Acetal Polymers for Safe and Effective Administration of Amphotericin B as a Vaccine Adjuvant.

Van Herck S, Van Hoecke L, Louage B, Lybaert L, De Coen R, Kasmi S, Esser-Kahn AP, David SA, Nuhn L, Schepens B, Saelens X, De Geest BG. Van Herck S, et al. Among authors: van hoecke l. Bioconjug Chem. 2018 Mar 21;29(3):748-760. doi: 10.1021/acs.bioconjchem.7b00641. Epub 2017 Dec 13. Bioconjug Chem. 2018. PMID: 29172458

8

Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist.

Nuhn L, Van Hoecke L, Deswarte K, Schepens B, Li Y, Lambrecht BN, De Koker S, David SA, Saelens X, De Geest BG. Nuhn L, et al. Among authors: van hoecke l. Biomaterials. 2018 Sep;178:643-651. doi: 10.1016/j.biomaterials.2018.03.026. Epub 2018 Mar 16. Biomaterials. 2018. PMID: 29573820

9

Surfactant protein B (SP-B) enhances the cellular siRNA delivery of proteolipid coated nanogels for inhalation therapy.

Merckx P, De Backer L, Van Hoecke L, Guagliardo R, Echaide M, Baatsen P, Olmeda B, Saelens X, Pérez-Gil J, De Smedt SC, Raemdonck K. Merckx P, et al. Among authors: van hoecke l. Acta Biomater. 2018 Sep 15;78:236-246. doi: 10.1016/j.actbio.2018.08.012. Epub 2018 Aug 15. Acta Biomater. 2018. PMID: 30118853

10

Treatment with mRNA coding for the necroptosis mediator MLKL induces antitumor immunity directed against neo-epitopes.

Van Hoecke L, Van Lint S, Roose K, Van Parys A, Vandenabeele P, Grooten J, Tavernier J, De Koker S, Saelens X. Van Hoecke L, et al. Among authors: van lint s, van parys a. Nat Commun. 2018 Aug 24;9(1):3417. doi: 10.1038/s41467-018-05979-8. Nat Commun. 2018. PMID: 30143632 Free PMC article.

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