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Page 1
An immunological puzzle: The adaptive immune system fuels Alzheimer's disease pathology.
Van Hoecke L, Castelein J, Xie J, Van Acker L, Van Imschoot G, Van Wonterghem E, Vlaeminck I, Verhaege D, Claeys W, Wierda K, Callaerts-Vegh Z, Vandenbroucke RE. Van Hoecke L, et al. Among authors: van imschoot g. Brain Behav Immun. 2024 Mar;117:122-134. doi: 10.1016/j.bbi.2023.12.026. Epub 2023 Dec 23. Brain Behav Immun. 2024. PMID: 38142916
Development and Validation of a Small Single-domain Antibody That Effectively Inhibits Matrix Metalloproteinase 8.
Demeestere D, Dejonckheere E, Steeland S, Hulpiau P, Haustraete J, Devoogdt N, Wichert R, Becker-Pauly C, Van Wonterghem E, Dewaele S, Van Imschoot G, Aerts J, Arckens L, Saeys Y, Libert C, Vandenbroucke RE. Demeestere D, et al. Among authors: van wonterghem e, van imschoot g. Mol Ther. 2016 May;24(5):890-902. doi: 10.1038/mt.2016.2. Epub 2016 Jan 18. Mol Ther. 2016. PMID: 26775809 Free PMC article.
TNFR1 inhibition with a Nanobody protects against EAE development in mice.
Steeland S, Van Ryckeghem S, Van Imschoot G, De Rycke R, Toussaint W, Vanhoutte L, Vanhove C, De Vos F, Vandenbroucke RE, Libert C. Steeland S, et al. Among authors: van imschoot g, van ryckeghem s. Sci Rep. 2017 Oct 20;7(1):13646. doi: 10.1038/s41598-017-13984-y. Sci Rep. 2017. PMID: 29057962 Free PMC article.
The choroid plexus epithelium as a novel player in the stomach-brain axis during Helicobacter infection.
Gorlé N, Blaecher C, Bauwens E, Vandendriessche C, Balusu S, Vandewalle J, Van Cauwenberghe C, Van Wonterghem E, Van Imschoot G, Liu C, Ducatelle R, Libert C, Haesebrouck F, Smet A, Vandenbroucke RE. Gorlé N, et al. Among authors: van cauwenberghe c, van wonterghem e, van imschoot g. Brain Behav Immun. 2018 Mar;69:35-47. doi: 10.1016/j.bbi.2017.12.010. Epub 2017 Dec 16. Brain Behav Immun. 2018. PMID: 29258921
Counteracting the effects of TNF receptor-1 has therapeutic potential in Alzheimer's disease.
Steeland S, Gorlé N, Vandendriessche C, Balusu S, Brkic M, Van Cauwenberghe C, Van Imschoot G, Van Wonterghem E, De Rycke R, Kremer A, Lippens S, Stopa E, Johanson CE, Libert C, Vandenbroucke RE. Steeland S, et al. Among authors: van cauwenberghe c, van imschoot g, van wonterghem e. EMBO Mol Med. 2018 Apr;10(4):e8300. doi: 10.15252/emmm.201708300. EMBO Mol Med. 2018. PMID: 29472246 Free PMC article.
A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation.
Voet S, Mc Guire C, Hagemeyer N, Martens A, Schroeder A, Wieghofer P, Daems C, Staszewski O, Vande Walle L, Jordao MJC, Sze M, Vikkula HK, Demeestere D, Van Imschoot G, Scott CL, Hoste E, Gonçalves A, Guilliams M, Lippens S, Libert C, Vandenbroucke RE, Kim KW, Jung S, Callaerts-Vegh Z, Callaerts P, de Wit J, Lamkanfi M, Prinz M, van Loo G. Voet S, et al. Among authors: van imschoot g, van loo g. Nat Commun. 2018 May 23;9(1):2036. doi: 10.1038/s41467-018-04376-5. Nat Commun. 2018. PMID: 29789522 Free PMC article.
Importance of extracellular vesicle secretion at the blood-cerebrospinal fluid interface in the pathogenesis of Alzheimer's disease.
Vandendriessche C, Balusu S, Van Cauwenberghe C, Brkic M, Pauwels M, Plehiers N, Bruggeman A, Dujardin P, Van Imschoot G, Van Wonterghem E, Hendrix A, Baeke F, De Rycke R, Gevaert K, Vandenbroucke RE. Vandendriessche C, et al. Among authors: van cauwenberghe c, van imschoot g, van wonterghem e. Acta Neuropathol Commun. 2021 Aug 23;9(1):143. doi: 10.1186/s40478-021-01245-z. Acta Neuropathol Commun. 2021. PMID: 34425919 Free PMC article.
Low-grade peripheral inflammation affects brain pathology in the AppNL-G-Fmouse model of Alzheimer's disease.
Xie J, Gorlé N, Vandendriessche C, Van Imschoot G, Van Wonterghem E, Van Cauwenberghe C, Parthoens E, Van Hamme E, Lippens S, Van Hoecke L, Vandenbroucke RE. Xie J, et al. Among authors: van cauwenberghe c, van imschoot g, van wonterghem e, van hamme e, van hoecke l. Acta Neuropathol Commun. 2021 Oct 7;9(1):163. doi: 10.1186/s40478-021-01253-z. Acta Neuropathol Commun. 2021. PMID: 34620254 Free PMC article.
29 results