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Structures of substrate- and inhibitor-bound adenosine deaminase from a human malaria parasite show a dramatic conformational change and shed light on drug selectivity.
Larson ET, Deng W, Krumm BE, Napuli A, Mueller N, Van Voorhis WC, Buckner FS, Fan E, Lauricella A, DeTitta G, Luft J, Zucker F, Hol WG, Verlinde CL, Merritt EA. Larson ET, et al. Among authors: van voorhis wc. J Mol Biol. 2008 Sep 12;381(4):975-88. doi: 10.1016/j.jmb.2008.06.048. Epub 2008 Jun 24. J Mol Biol. 2008. PMID: 18602399 Free PMC article.
Engineering cytokine secretion from Trypanosoma cruzi.
La Flamme AC, Buckner F, Swindle J, Ajioka J, Barrett L, Van Voorhis WC. La Flamme AC, et al. Among authors: van voorhis wc. Mem Inst Oswaldo Cruz. 1994 Oct-Dec;89(4):650-1. doi: 10.1590/s0074-02761994000400025. Mem Inst Oswaldo Cruz. 1994. PMID: 8524068 Free article. No abstract available.
Induction of resistance to azole drugs in Trypanosoma cruzi.
Buckner FS, Wilson AJ, White TC, Van Voorhis WC. Buckner FS, et al. Among authors: van voorhis wc. Antimicrob Agents Chemother. 1998 Dec;42(12):3245-50. doi: 10.1128/AAC.42.12.3245. Antimicrob Agents Chemother. 1998. PMID: 9835521 Free PMC article.
328 results