Van den Eynden J - Search Results

1

Lack of detectable neoantigen depletion signals in the untreated cancer genome.

Van den Eynden J, Jiménez-Sánchez A, Miller ML, Larsson E. Van den Eynden J, et al. Nat Genet. 2019 Dec;51(12):1741-1748. doi: 10.1038/s41588-019-0532-6. Epub 2019 Nov 25. Nat Genet. 2019. PMID: 31768072 Free PMC article.

2

Somatic Mutation Patterns in Hemizygous Genomic Regions Unveil Purifying Selection during Tumor Evolution.

Van den Eynden J, Basu S, Larsson E. Van den Eynden J, et al. PLoS Genet. 2016 Dec 27;12(12):e1006506. doi: 10.1371/journal.pgen.1006506. eCollection 2016 Dec. PLoS Genet. 2016. PMID: 28027311 Free PMC article.

3

Recurrent promoter mutations in melanoma are defined by an extended context-specific mutational signature.

Fredriksson NJ, Elliott K, Filges S, Van den Eynden J, Ståhlberg A, Larsson E. Fredriksson NJ, et al. Among authors: van den eynden j. PLoS Genet. 2017 May 10;13(5):e1006773. doi: 10.1371/journal.pgen.1006773. eCollection 2017 May. PLoS Genet. 2017. PMID: 28489852 Free PMC article.

4

Mutational Signatures Are Critical for Proper Estimation of Purifying Selection Pressures in Cancer Somatic Mutation Data When Using the dN/dS Metric.

Van den Eynden J, Larsson E. Van den Eynden J, et al. Front Genet. 2017 Jun 8;8:74. doi: 10.3389/fgene.2017.00074. eCollection 2017. Front Genet. 2017. PMID: 28642787 Free PMC article.

5

Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events.

Ashouri A, Sayin VI, Van den Eynden J, Singh SX, Papagiannakopoulos T, Larsson E. Ashouri A, et al. Among authors: van den eynden j. Nat Commun. 2016 Oct 25;7:13197. doi: 10.1038/ncomms13197. Nat Commun. 2016. PMID: 28959951 Free PMC article.

6

Clinical response of the novel activating ALK-I1171T mutation in neuroblastoma to the ALK inhibitor ceritinib.

Guan J, Fransson S, Siaw JT, Treis D, Van den Eynden J, Chand D, Umapathy G, Ruuth K, Svenberg P, Wessman S, Shamikh A, Jacobsson H, Gordon L, Stenman J, Svensson PJ, Hansson M, Larsson E, Martinsson T, Palmer RH, Kogner P, Hallberg B. Guan J, et al. Among authors: van den eynden j. Cold Spring Harb Mol Case Stud. 2018 Aug 1;4(4):a002550. doi: 10.1101/mcs.a002550. Print 2018 Aug. Cold Spring Harb Mol Case Stud. 2018. PMID: 29907598 Free PMC article.

7

An antisense RNA capable of modulating the expression of the tumor suppressor microRNA-34a.

Serviss JT, Andrews N, Van den Eynden J, Richter FC, Houtman M, Vesterlund M, Schwarzmueller L, Johnsson P, Larsson E, Grandér D, Pokrovskaja Tamm K. Serviss JT, et al. Among authors: van den eynden j. Cell Death Dis. 2018 Jul 3;9(7):736. doi: 10.1038/s41419-018-0777-5. Cell Death Dis. 2018. PMID: 29970884 Free PMC article.

8

Phosphoproteome and gene expression profiling of ALK inhibition in neuroblastoma cell lines reveals conserved oncogenic pathways.

Van den Eynden J, Umapathy G, Ashouri A, Cervantes-Madrid D, Szydzik J, Ruuth K, Koster J, Larsson E, Guan J, Palmer RH, Hallberg B. Van den Eynden J, et al. Sci Signal. 2018 Nov 20;11(557):eaar5680. doi: 10.1126/scisignal.aar5680. Sci Signal. 2018. PMID: 30459281

9

Elevated pyrimidine dimer formation at distinct genomic bases underlies promoter mutation hotspots in UV-exposed cancers.

Elliott K, Boström M, Filges S, Lindberg M, Van den Eynden J, Ståhlberg A, Clausen AR, Larsson E. Elliott K, et al. Among authors: van den eynden j. PLoS Genet. 2018 Dec 26;14(12):e1007849. doi: 10.1371/journal.pgen.1007849. eCollection 2018 Dec. PLoS Genet. 2018. PMID: 30586386 Free PMC article.

10

Targeting Filamin A Reduces Macrophage Activity and Atherosclerosis.

Bandaru S, Ala C, Salimi R, Akula MK, Ekstrand M, Devarakonda S, Karlsson J, Van den Eynden J, Bergström G, Larsson E, Levin M, Borén J, Bergo MO, Akyürek LM. Bandaru S, et al. Among authors: van den eynden j. Circulation. 2019 Jul 2;140(1):67-79. doi: 10.1161/CIRCULATIONAHA.119.039697. Epub 2019 Apr 24. Circulation. 2019. PMID: 31014088

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