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rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration.
Oliveras-Salvá M, Van der Perren A, Casadei N, Stroobants S, Nuber S, D'Hooge R, Van den Haute C, Baekelandt V. Oliveras-Salvá M, et al. Among authors: van der perren a, van den haute c. Mol Neurodegener. 2013 Nov 25;8:44. doi: 10.1186/1750-1326-8-44. Mol Neurodegener. 2013. PMID: 24267638 Free PMC article.
Viral vector-based models of Parkinson's disease.
Van der Perren A, Van den Haute C, Baekelandt V. Van der Perren A, et al. Among authors: van den haute c. Curr Top Behav Neurosci. 2015;22:271-301. doi: 10.1007/7854_2014_310. Curr Top Behav Neurosci. 2015. PMID: 24839101 Review.
Alpha-synuclein-induced neurodegeneration is exacerbated in PINK1 knockout mice.
Oliveras-Salvá M, Macchi F, Coessens V, Deleersnijder A, Gérard M, Van der Perren A, Van den Haute C, Baekelandt V. Oliveras-Salvá M, et al. Among authors: van der perren a, van den haute c. Neurobiol Aging. 2014 Nov;35(11):2625-2636. doi: 10.1016/j.neurobiolaging.2014.04.032. Epub 2014 Jun 14. Neurobiol Aging. 2014. PMID: 25037286
Longitudinal follow-up and characterization of a robust rat model for Parkinson's disease based on overexpression of alpha-synuclein with adeno-associated viral vectors.
Van der Perren A, Toelen J, Casteels C, Macchi F, Van Rompuy AS, Sarre S, Casadei N, Nuber S, Himmelreich U, Osorio Garcia MI, Michotte Y, D'Hooge R, Bormans G, Van Laere K, Gijsbers R, Van den Haute C, Debyser Z, Baekelandt V. Van der Perren A, et al. Among authors: van rompuy as, van laere k, van den haute c. Neurobiol Aging. 2015 Mar;36(3):1543-58. doi: 10.1016/j.neurobiolaging.2014.11.015. Epub 2014 Dec 17. Neurobiol Aging. 2015. PMID: 25599874
FK506 reduces neuroinflammation and dopaminergic neurodegeneration in an α-synuclein-based rat model for Parkinson's disease.
Van der Perren A, Macchi F, Toelen J, Carlon MS, Maris M, de Loor H, Kuypers DR, Gijsbers R, Van den Haute C, Debyser Z, Baekelandt V. Van der Perren A, et al. Among authors: van den haute c. Neurobiol Aging. 2015 Mar;36(3):1559-68. doi: 10.1016/j.neurobiolaging.2015.01.014. Epub 2015 Jan 21. Neurobiol Aging. 2015. PMID: 25660193 Free article.
32 results