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Choline cannot be replaced by propanolamine in mice.
Li Z, Vance DE. Li Z, et al. Among authors: vance de. Biochim Biophys Acta. 2007 Apr;1771(4):486-90. doi: 10.1016/j.bbalip.2007.01.003. Epub 2007 Jan 10. Biochim Biophys Acta. 2007. PMID: 17292664
Alkylphosphocholines inhibit choline uptake and phosphatidylcholine biosynthesis in rat sympathetic neurons and impair axonal extension.
Posse de Chaves E, Vance DE, Campenot RB, Vance JE. Posse de Chaves E, et al. Among authors: vance de, vance je. Biochem J. 1995 Dec 1;312 ( Pt 2)(Pt 2):411-7. doi: 10.1042/bj3120411. Biochem J. 1995. PMID: 8526849 Free PMC article.
At least 50% of the major axonal membrane lipid, phosphatidylcholine, of rat sympathetic neurons is synthesized in situ in axons [Posse de Chaves, Vance, Campenot and Vance (1995) J. Cell Biol. 128, 913-918]. ...
At least 50% of the major axonal membrane lipid, phosphatidylcholine, of rat sympathetic neurons is synthesized in situ in axons [Posse d
516 results