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cAMP-binding protein Epac induces cardiomyocyte hypertrophy.
Morel E, Marcantoni A, Gastineau M, Birkedal R, Rochais F, Garnier A, Lompré AM, Vandecasteele G, Lezoualc'h F. Morel E, et al. Among authors: vandecasteele g. Circ Res. 2005 Dec 9;97(12):1296-304. doi: 10.1161/01.RES.0000194325.31359.86. Epub 2005 Nov 3. Circ Res. 2005. PMID: 16269655 Free article.
Phosphodiesterase 4B in the cardiac L-type Ca²⁺ channel complex regulates Ca²⁺ current and protects against ventricular arrhythmias in mice.
Leroy J, Richter W, Mika D, Castro LR, Abi-Gerges A, Xie M, Scheitrum C, Lefebvre F, Schittl J, Mateo P, Westenbroek R, Catterall WA, Charpentier F, Conti M, Fischmeister R, Vandecasteele G. Leroy J, et al. Among authors: vandecasteele g. J Clin Invest. 2011 Jul;121(7):2651-61. doi: 10.1172/JCI44747. Epub 2011 Jun 13. J Clin Invest. 2011. PMID: 21670503 Free PMC article.
Phosphodiesterase-2 is up-regulated in human failing hearts and blunts β-adrenergic responses in cardiomyocytes.
Mehel H, Emons J, Vettel C, Wittköpper K, Seppelt D, Dewenter M, Lutz S, Sossalla S, Maier LS, Lechêne P, Leroy J, Lefebvre F, Varin A, Eschenhagen T, Nattel S, Dobrev D, Zimmermann WH, Nikolaev VO, Vandecasteele G, Fischmeister R, El-Armouche A. Mehel H, et al. Among authors: vandecasteele g. J Am Coll Cardiol. 2013 Oct 22;62(17):1596-606. doi: 10.1016/j.jacc.2013.05.057. Epub 2013 Jun 26. J Am Coll Cardiol. 2013. PMID: 23810893 Free article.
Inactivation of the Carney complex gene 1 (PRKAR1A) alters spatiotemporal regulation of cAMP and cAMP-dependent protein kinase: a study using genetically encoded FRET-based reporters.
Cazabat L, Ragazzon B, Varin A, Potier-Cartereau M, Vandier C, Vezzosi D, Risk-Rabin M, Guellich A, Schittl J, Lechêne P, Richter W, Nikolaev VO, Zhang J, Bertherat J, Vandecasteele G. Cazabat L, et al. Among authors: vandecasteele g. Hum Mol Genet. 2014 Mar 1;23(5):1163-74. doi: 10.1093/hmg/ddt510. Epub 2013 Oct 10. Hum Mol Genet. 2014. PMID: 24122441 Free PMC article.
Cardiac adenylyl cyclase overexpression precipitates and aggravates age-related myocardial dysfunction.
Mougenot N, Mika D, Czibik G, Marcos E, Abid S, Houssaini A, Vallin B, Guellich A, Mehel H, Sawaki D, Vandecasteele G, Fischmeister R, Hajjar RJ, Dubois-Randé JL, Limon I, Adnot S, Derumeaux G, Lipskaia L. Mougenot N, et al. Among authors: vandecasteele g. Cardiovasc Res. 2019 Oct 1;115(12):1778-1790. doi: 10.1093/cvr/cvy306. Cardiovasc Res. 2019. PMID: 30605506 Free PMC article.
62 results