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Hypericin-induced photosensitization of HeLa cells leads to apoptosis or necrosis. Involvement of cytochrome c and procaspase-3 activation in the mechanism of apoptosis.
Vantieghem A, Assefa Z, Vandenabeele P, Declercq W, Courtois S, Vandenheede JR, Merlevede W, de Witte P, Agostinis P. Vantieghem A, et al. Among authors: vandenabeele p. FEBS Lett. 1998 Nov 27;440(1-2):19-24. doi: 10.1016/s0014-5793(98)01416-1. FEBS Lett. 1998. PMID: 9862416 Free article.
The activation of the c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signaling pathways protects HeLa cells from apoptosis following photodynamic therapy with hypericin.
Assefa Z, Vantieghem A, Declercq W, Vandenabeele P, Vandenheede JR, Merlevede W, de Witte P, Agostinis P. Assefa Z, et al. Among authors: vandenabeele p. J Biol Chem. 1999 Mar 26;274(13):8788-96. doi: 10.1074/jbc.274.13.8788. J Biol Chem. 1999. PMID: 10085120 Free article.
544 results