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Adeno-associated viruses as liver-directed gene delivery vehicles: focus on lipoprotein metabolism.
Lagor WR, Johnston JC, Lock M, Vandenberghe LH, Rader DJ. Lagor WR, et al. Among authors: vandenberghe lh. Methods Mol Biol. 2013;1027:273-307. doi: 10.1007/978-1-60327-369-5_13. Methods Mol Biol. 2013. PMID: 23912992
Adeno-associated viruses undergo substantial evolution in primates during natural infections.
Gao G, Alvira MR, Somanathan S, Lu Y, Vandenberghe LH, Rux JJ, Calcedo R, Sanmiguel J, Abbas Z, Wilson JM. Gao G, et al. Among authors: vandenberghe lh. Proc Natl Acad Sci U S A. 2003 May 13;100(10):6081-6. doi: 10.1073/pnas.0937739100. Epub 2003 Apr 25. Proc Natl Acad Sci U S A. 2003. PMID: 12716974 Free PMC article.
Clades of Adeno-associated viruses are widely disseminated in human tissues.
Gao G, Vandenberghe LH, Alvira MR, Lu Y, Calcedo R, Zhou X, Wilson JM. Gao G, et al. Among authors: vandenberghe lh. J Virol. 2004 Jun;78(12):6381-8. doi: 10.1128/JVI.78.12.6381-6388.2004. J Virol. 2004. PMID: 15163731 Free PMC article.
New recombinant serotypes of AAV vectors.
Gao G, Vandenberghe LH, Wilson JM. Gao G, et al. Among authors: vandenberghe lh. Curr Gene Ther. 2005 Jun;5(3):285-97. doi: 10.2174/1566523054065057. Curr Gene Ther. 2005. PMID: 15975006 Review.
Heparin binding directs activation of T cells against adeno-associated virus serotype 2 capsid.
Vandenberghe LH, Wang L, Somanathan S, Zhi Y, Figueredo J, Calcedo R, Sanmiguel J, Desai RA, Chen CS, Johnston J, Grant RL, Gao G, Wilson JM. Vandenberghe LH, et al. Nat Med. 2006 Aug;12(8):967-71. doi: 10.1038/nm1445. Epub 2006 Jul 16. Nat Med. 2006. PMID: 16845388
Comparative analysis of adeno-associated viral vector serotypes 1, 2, 5, 7, and 8 in mouse brain.
Taymans JM, Vandenberghe LH, Haute CV, Thiry I, Deroose CM, Mortelmans L, Wilson JM, Debyser Z, Baekelandt V. Taymans JM, et al. Among authors: vandenberghe lh. Hum Gene Ther. 2007 Mar;18(3):195-206. doi: 10.1089/hum.2006.178. Hum Gene Ther. 2007. PMID: 17343566
., Vandenberghe, L.H., and Wilson, J.M. [2005]. Curr. Gene Ther. 5, 285-297). Here, we extensively compare the neural tropism of human-derived rAAVs (types 2/1, 2, and 2/5) with nonhuman primate-derived rAAVs (types 2/7 and 2/8) in adult mouse brain. ...
., Vandenberghe, L.H., and Wilson, J.M. [2005]. Curr. Gene Ther. 5, 285-297). Here, we extensively compare the neural tropism of huma …
A comparative analysis of novel fluorescent proteins as reporters for gene transfer studies.
Bell P, Vandenberghe LH, Wu D, Johnston J, Limberis M, Wilson JM. Bell P, et al. Among authors: vandenberghe lh. J Histochem Cytochem. 2007 Sep;55(9):931-9. doi: 10.1369/jhc.7A7180.2007. Epub 2007 May 17. J Histochem Cytochem. 2007. PMID: 17510373
Novel adeno-associated virus serotypes efficiently transduce murine photoreceptors.
Allocca M, Mussolino C, Garcia-Hoyos M, Sanges D, Iodice C, Petrillo M, Vandenberghe LH, Wilson JM, Marigo V, Surace EM, Auricchio A. Allocca M, et al. Among authors: vandenberghe lh. J Virol. 2007 Oct;81(20):11372-80. doi: 10.1128/JVI.01327-07. Epub 2007 Aug 15. J Virol. 2007. PMID: 17699581 Free PMC article.
AAV as an immunogen.
Vandenberghe LH, Wilson JM. Vandenberghe LH, et al. Curr Gene Ther. 2007 Oct;7(5):325-33. doi: 10.2174/156652307782151416. Curr Gene Ther. 2007. PMID: 17979679 Review.
Specific AAV serotypes stably transduce primary hippocampal and cortical cultures with high efficiency and low toxicity.
Royo NC, Vandenberghe LH, Ma JY, Hauspurg A, Yu L, Maronski M, Johnston J, Dichter MA, Wilson JM, Watson DJ. Royo NC, et al. Among authors: vandenberghe lh. Brain Res. 2008 Jan 23;1190:15-22. doi: 10.1016/j.brainres.2007.11.015. Epub 2007 Nov 17. Brain Res. 2008. PMID: 18054899 Free PMC article.
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