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Dietary Nitrate and Physical Performance.
Jones AM, Thompson C, Wylie LJ, Vanhatalo A. Jones AM, et al. Annu Rev Nutr. 2018 Aug 21;38:303-328. doi: 10.1146/annurev-nutr-082117-051622. Annu Rev Nutr. 2018. PMID: 30130468
Nitric oxide (NO) plays a plethora of important roles in the human body. Insufficient production of NO (for example, during older age and in various disease conditions) can adversely impact health and physical performance. ...This review describes the physiological mechani …
Nitric oxide (NO) plays a plethora of important roles in the human body. Insufficient production of NO (for example, during older age …
Influence of pacing strategy on O2 uptake and exercise tolerance.
Jones AM, Wilkerson DP, Vanhatalo A, Burnley M. Jones AM, et al. Scand J Med Sci Sports. 2008 Oct;18(5):615-26. doi: 10.1111/j.1600-0838.2007.00725.x. Epub 2007 Dec 7. Scand J Med Sci Sports. 2008. PMID: 18067518 Clinical Trial.
Seven male subjects completed cycle exercise bouts to the limit of tolerance on three occasions: (1) at a constant work rate (340+/-57 W; even-pace strategy; ES); (2) at a work rate that was initially 10% lower than that in the ES trial but which then increased with …
Seven male subjects completed cycle exercise bouts to the limit of tolerance on three occasions: (1) at a constant work rate (340+/-5 …
Influence of prior sprint exercise on the parameters of the 'all-out critical power test' in men.
Vanhatalo A, Jones AM. Vanhatalo A, et al. Exp Physiol. 2009 Feb;94(2):255-63. doi: 10.1113/expphysiol.2008.045229. Epub 2008 Nov 7. Exp Physiol. 2009. PMID: 18996948
We tested the hypothesis that a prior 30 s sprint exercise bout would significantly reduce the curvature constant (W') but not the power-asymptote (critical power, CP) of the power-duration relationship as assessed using a novel 3 min all-out cycling test. Seven phy …
We tested the hypothesis that a prior 30 s sprint exercise bout would significantly reduce the curvature constant (W') but not the po …
Dietary nitrate supplementation reduces the O2 cost of low-intensity exercise and enhances tolerance to high-intensity exercise in humans.
Bailey SJ, Winyard P, Vanhatalo A, Blackwell JR, Dimenna FJ, Wilkerson DP, Tarr J, Benjamin N, Jones AM. Bailey SJ, et al. J Appl Physiol (1985). 2009 Oct;107(4):1144-55. doi: 10.1152/japplphysiol.00722.2009. Epub 2009 Aug 6. J Appl Physiol (1985). 2009. PMID: 19661447 Clinical Trial.
In a double-blind, placebo (PL)-controlled, crossover study, eight men (aged 19-38 yr) consumed 500 ml/day of either BR (containing 11.2 +/- 0.6 mM of nitrate) or blackcurrant cordial (as a PL, with negligible nitrate content) for 6 consecutive days and completed …
In a double-blind, placebo (PL)-controlled, crossover study, eight men (aged 19-38 yr) consumed 500 ml/day of either BR (containing 1 …
Optimizing the "priming" effect: influence of prior exercise intensity and recovery duration on O2 uptake kinetics and severe-intensity exercise tolerance.
Bailey SJ, Vanhatalo A, Wilkerson DP, Dimenna FJ, Jones AM. Bailey SJ, et al. J Appl Physiol (1985). 2009 Dec;107(6):1743-56. doi: 10.1152/japplphysiol.00810.2009. Epub 2009 Oct 1. J Appl Physiol (1985). 2009. PMID: 19797685
It has been suggested that a prior bout of high-intensity exercise has the potential to enhance performance during subsequent high-intensity exercise by accelerating the O(2) uptake (Vo(2)) on-response. ...Overall Vo(2) kinetics were accelerated relative to control in all …
It has been suggested that a prior bout of high-intensity exercise has the potential to enhance performance during subsequent high-in …
Influence of hyperoxia on muscle metabolic responses and the power-duration relationship during severe-intensity exercise in humans: a 31P magnetic resonance spectroscopy study.
Vanhatalo A, Fulford J, DiMenna FJ, Jones AM. Vanhatalo A, et al. Exp Physiol. 2010 Apr;95(4):528-40. doi: 10.1113/expphysiol.2009.050500. Epub 2009 Dec 22. Exp Physiol. 2010. PMID: 20028850 Clinical Trial.
Critical power: implications for determination of V˙O2max and exercise tolerance.
Jones AM, Vanhatalo A, Burnley M, Morton RH, Poole DC. Jones AM, et al. Med Sci Sports Exerc. 2010 Oct;42(10):1876-90. doi: 10.1249/MSS.0b013e3181d9cf7f. Med Sci Sports Exerc. 2010. PMID: 20195180 Review.
For high-intensity muscular exercise, the time-to-exhaustion (t) increases as a predictable and hyperbolic function of decreasing power (P) or velocity (V ). ...The CP concept constitutes a practical framework in which to explore mechanisms of fatigue and help resol …
For high-intensity muscular exercise, the time-to-exhaustion (t) increases as a predictable and hyperbolic function of decreasing pow …
Dietary nitrate supplementation enhances muscle contractile efficiency during knee-extensor exercise in humans.
Bailey SJ, Fulford J, Vanhatalo A, Winyard PG, Blackwell JR, DiMenna FJ, Wilkerson DP, Benjamin N, Jones AM. Bailey SJ, et al. J Appl Physiol (1985). 2010 Jul;109(1):135-48. doi: 10.1152/japplphysiol.00046.2010. Epub 2010 May 13. J Appl Physiol (1985). 2010. PMID: 20466802 Clinical Trial.

On days 4-6, BR resulted in a significant increase in plasma [nitrite] (mean +/- SE, PL 231 +/- 76 vs. BR 547 +/- 55 nM; P < 0.05). ...The reduced muscle metabolic perturbation with NO(3)(-) supplementation allowed high-intensity exercise to be tolerated for a gr

On days 4-6, BR resulted in a significant increase in plasma [nitrite] (mean +/- SE, PL 231 +/- 76 vs. BR 547 +/- 55 nM; P < 0.05)

Fast-start strategy improves VO2 kinetics and high-intensity exercise performance.
Bailey SJ, Vanhatalo A, DiMenna FJ, Wilkerson DP, Jones AM. Bailey SJ, et al. Med Sci Sports Exerc. 2011 Mar;43(3):457-67. doi: 10.1249/MSS.0b013e3181ef3dce. Med Sci Sports Exerc. 2011. PMID: 20689463
In all conditions, subjects completed an all-out sprint over the final 60 s of the test as a measure of performance. RESULTS: For the 3-min exercise bouts, the mean response time (MRT) for the VO2 kinetics over the pacing phase was shortest in FS (35 ± 6 s), longest in SS …
In all conditions, subjects completed an all-out sprint over the final 60 s of the test as a measure of performance. RESULTS: For the …
Acute and chronic effects of dietary nitrate supplementation on blood pressure and the physiological responses to moderate-intensity and incremental exercise.
Vanhatalo A, Bailey SJ, Blackwell JR, DiMenna FJ, Pavey TG, Wilkerson DP, Benjamin N, Winyard PG, Jones AM. Vanhatalo A, et al. Am J Physiol Regul Integr Comp Physiol. 2010 Oct;299(4):R1121-31. doi: 10.1152/ajpregu.00206.2010. Epub 2010 Aug 11. Am J Physiol Regul Integr Comp Physiol. 2010. PMID: 20702806 Clinical Trial.
Following baseline tests, the subjects were assigned in a balanced crossover design to receive BR (0.5 l/day; 5.2 mmol of NO(3)(-)/day) and placebo (PL; 0.5 l/day low-calorie juice cordial) treatments. The exercise protocol (two moderate-intensity step tests followed by …
Following baseline tests, the subjects were assigned in a balanced crossover design to receive BR (0.5 l/day; 5.2 mmol of NO(3)(-)/da …
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