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The human basonuclin 2 gene has the potential to generate nearly 90,000 mRNA isoforms encoding over 2000 different proteins.
Vanhoutteghem A, Djian P. Vanhoutteghem A, et al. Genomics. 2007 Jan;89(1):44-58. doi: 10.1016/j.ygeno.2006.07.006. Epub 2006 Aug 30. Genomics. 2007. PMID: 16942855
The importance of basonuclin 2 in adult mice and its relation to basonuclin 1.
Vanhoutteghem A, Delhomme B, Hervé F, Nondier I, Petit JM, Araki M, Araki K, Djian P. Vanhoutteghem A, et al. Mech Dev. 2016 May;140:53-73. doi: 10.1016/j.mod.2016.02.002. Epub 2016 Mar 2. Mech Dev. 2016. PMID: 26923665 Free article.
Ancient origin of the gene encoding involucrin, a precursor of the cross-linked envelope of epidermis and related epithelia.
Vanhoutteghem A, Djian P, Green H. Vanhoutteghem A, et al. Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15481-6. doi: 10.1073/pnas.0807643105. Epub 2008 Sep 22. Proc Natl Acad Sci U S A. 2008. PMID: 18809918 Free PMC article.
Basonuclins 1 and 2, whose genes share a common origin, are proteins with widely different properties and functions.
Vanhoutteghem A, Djian P. Vanhoutteghem A, et al. Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12423-8. doi: 10.1073/pnas.0605086103. Epub 2006 Aug 4. Proc Natl Acad Sci U S A. 2006. PMID: 16891417 Free PMC article.
Basonuclin 2: an extremely conserved homolog of the zinc finger protein basonuclin.
Vanhoutteghem A, Djian P. Vanhoutteghem A, et al. Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3468-73. doi: 10.1073/pnas.0400268101. Epub 2004 Feb 26. Proc Natl Acad Sci U S A. 2004. PMID: 14988505 Free PMC article.
Serial cultivation of chicken keratinocytes, a composite cell type that accumulates lipids and synthesizes a novel beta-keratin.
Vanhoutteghem A, Londero T, Ghinea N, Djian P. Vanhoutteghem A, et al. Differentiation. 2004 Apr;72(4):123-37. doi: 10.1111/j.1432-0436.2004.07204002.x. Differentiation. 2004. PMID: 15157236
The zinc-finger protein basonuclin 2 is required for proper mitotic arrest, prevention of premature meiotic initiation and meiotic progression in mouse male germ cells.
Vanhoutteghem A, Messiaen S, Hervé F, Delhomme B, Moison D, Petit JM, Rouiller-Fabre V, Livera G, Djian P. Vanhoutteghem A, et al. Development. 2014 Nov;141(22):4298-310. doi: 10.1242/dev.112888. Epub 2014 Oct 24. Development. 2014. PMID: 25344072 Free article.
Control of gene expression by the retinoic acid-related orphan receptor alpha in HepG2 human hepatoma cells.
Chauvet C, Vanhoutteghem A, Duhem C, Saint-Auret G, Bois-Joyeux B, Djian P, Staels B, Danan JL. Chauvet C, et al. Among authors: vanhoutteghem a. PLoS One. 2011;6(7):e22545. doi: 10.1371/journal.pone.0022545. Epub 2011 Jul 26. PLoS One. 2011. PMID: 21818335 Free PMC article.
Basonuclin 2 has a function in the multiplication of embryonic craniofacial mesenchymal cells and is orthologous to disco proteins.
Vanhoutteghem A, Maciejewski-Duval A, Bouche C, Delhomme B, Hervé F, Daubigney F, Soubigou G, Araki M, Araki K, Yamamura K, Djian P. Vanhoutteghem A, et al. Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14432-7. doi: 10.1073/pnas.0905840106. Epub 2009 Aug 12. Proc Natl Acad Sci U S A. 2009. PMID: 19706529 Free PMC article.
Basonuclins and disco: Orthologous zinc finger proteins essential for development in vertebrates and arthropods.
Vanhoutteghem A, Bouche C, Maciejewski-Duval A, Hervé F, Djian P. Vanhoutteghem A, et al. Biochimie. 2011 Feb;93(2):127-33. doi: 10.1016/j.biochi.2010.09.010. Epub 2010 Sep 24. Biochimie. 2011. PMID: 20870008 Review.
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