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Extensive drug resistance during low-level HIV viraemia while taking NNRTI-based ART supports lowering the viral load threshold for regimen switch in resource-limited settings: a pre-planned analysis from the SESOTHO trial.
Brown JA, Amstutz A, Nsakala BL, Seeburg U, Vanobberghen F, Muhairwe J, Klimkait T, Labhardt ND. Brown JA, et al. Among authors: vanobberghen f. J Antimicrob Chemother. 2021 Apr 13;76(5):1294-1298. doi: 10.1093/jac/dkab025. J Antimicrob Chemother. 2021. PMID: 33599270 Clinical Trial.
Cohort profile: The Kilombero and Ulanga Antiretroviral Cohort (KIULARCO) - A prospective HIV cohort in rural Tanzania.
Letang E, Kalinjuma AV, Glass TR, Gamell A, Mapesi H, Sikalengo GR, Luwanda LB, Mnzava D, Ntamatungiro AJ, Ndaki R, Francis G, Vanobberghen F, Furrer H, Klimkait T, Felger I, Tanner M, Hatz C, Weisser M, Battegay M, Kiularco Study Group. Letang E, et al. Among authors: vanobberghen f. Swiss Med Wkly. 2017 Jul 4;147:w14485. doi: 10.4414/smw.2017.14485. eCollection 2017. Swiss Med Wkly. 2017. PMID: 28695551 Free article.
SESOTHO trial ("Switch Either near Suppression Or THOusand") - switch to second-line versus WHO-guided standard of care for unsuppressed patients on first-line ART with viremia below 1000 copies/mL: protocol of a multicenter, parallel-group, open-label, randomized clinical trial in Lesotho, Southern Africa.
Amstutz A, Nsakala BL, Vanobberghen F, Muhairwe J, Glass TR, Achieng B, Sepeka M, Tlali K, Sao L, Thin K, Klimkait T, Battegay M, Labhardt ND. Amstutz A, et al. Among authors: vanobberghen f. BMC Infect Dis. 2018 Feb 12;18(1):76. doi: 10.1186/s12879-018-2979-y. BMC Infect Dis. 2018. PMID: 29433430 Free PMC article. Clinical Trial.
Prevalence and Evolution of Renal Impairment in People Living With HIV in Rural Tanzania.
Mapesi H, Kalinjuma AV, Ngerecha A, Franzeck F, Hatz C, Tanner M, Mayr M, Furrer H, Battegay M, Letang E, Weisser M, Glass TR; KIULARCO Study Group. Mapesi H, et al. Open Forum Infect Dis. 2018 Apr 6;5(4):ofy072. doi: 10.1093/ofid/ofy072. eCollection 2018 Apr. Open Forum Infect Dis. 2018. PMID: 29707599 Free PMC article.
The HOSENG trial - Effect of the provision of oral self-testing for absent and refusing individuals during a door-to-door HIV-testing campaign on testing coverage: protocol of a cluster-randomized clinical trial in rural Lesotho.
Amstutz A, Lejone TI, Khesa L, Muhairwe J, Nsakala BL, Tlali K, Bresser M, Vanobberghen F, Kopo M, Kao M, Klimkait T, Battegay M, Labhardt ND, Glass TR. Amstutz A, et al. Among authors: vanobberghen f. Trials. 2019 Aug 13;20(1):496. doi: 10.1186/s13063-019-3469-2. Trials. 2019. PMID: 31409421 Free PMC article.
The viral load monitoring cascade in a resource-limited setting: A prospective multicentre cohort study after introduction of routine viral load monitoring in rural Lesotho.
Glass TR, Motaboli L, Nsakala B, Lerotholi M, Vanobberghen F, Amstutz A, Lejone TI, Muhairwe J, Klimkait T, Labhardt ND. Glass TR, et al. Among authors: vanobberghen f. PLoS One. 2019 Aug 28;14(8):e0220337. doi: 10.1371/journal.pone.0220337. eCollection 2019. PLoS One. 2019. PMID: 31461455 Free PMC article.
Prevalence and management of drug-drug interactions with antiretroviral treatment in 2069 people living with HIV in rural Tanzania: a prospective cohort study.
Schlaeppi C, Vanobberghen F, Sikalengo G, Glass TR, Ndege RC, Foe G, Kuemmerle A, Paris DH, Battegay M, Marzolini C, Weisser M; Kilombero and Ulanga Antiretroviral Cohort (KIULARCO) study group. Schlaeppi C, et al. Among authors: vanobberghen f. HIV Med. 2020 Jan;21(1):53-63. doi: 10.1111/hiv.12801. Epub 2019 Sep 18. HIV Med. 2020. PMID: 31532898 Free PMC article.
Switch to second-line versus continued first-line antiretroviral therapy for patients with low-level HIV-1 viremia: An open-label randomized controlled trial in Lesotho.
Amstutz A, Nsakala BL, Vanobberghen F, Muhairwe J, Glass TR, Namane T, Mpholo T, Battegay M, Klimkait T, Labhardt ND. Amstutz A, et al. Among authors: vanobberghen f. PLoS Med. 2020 Sep 16;17(9):e1003325. doi: 10.1371/journal.pmed.1003325. eCollection 2020 Sep. PLoS Med. 2020. PMID: 32936795 Free PMC article. Clinical Trial.
Home-based oral self-testing for absent and declining individuals during a door-to-door HIV testing campaign in rural Lesotho (HOSENG): a cluster-randomised trial.
Amstutz A, Lejone TI, Khesa L, Muhairwe J, Bresser M, Vanobberghen F, Kopo M, Kao M, Nsakala BL, Tlali K, Klimkait T, Battegay M, Labhardt ND, Glass TR. Amstutz A, et al. Among authors: vanobberghen f. Lancet HIV. 2020 Nov;7(11):e752-e761. doi: 10.1016/S2352-3018(20)30233-2. Epub 2020 Oct 9. Lancet HIV. 2020. PMID: 33045193 Clinical Trial.
52 results