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A 7-month cigarette smoke inhalation study in C57BL/6 mice demonstrates reduced lung inflammation and emphysema following smoking cessation or aerosol exposure from a prototypic modified risk tobacco product.
Phillips B, Veljkovic E, Peck MJ, Buettner A, Elamin A, Guedj E, Vuillaume G, Ivanov NV, Martin F, Boué S, Schlage WK, Schneider T, Titz B, Talikka M, Vanscheeuwijck P, Hoeng J, Peitsch MC. Phillips B, et al. Among authors: vanscheeuwijck p. Food Chem Toxicol. 2015 Jun;80:328-345. doi: 10.1016/j.fct.2015.03.009. Epub 2015 Apr 2. Food Chem Toxicol. 2015. PMID: 25843363 Free article.
Cigarette-smoke-induced atherogenic lipid profiles in plasma and vascular tissue of apolipoprotein E-deficient mice are attenuated by smoking cessation.
Lietz M, Berges A, Lebrun S, Meurrens K, Steffen Y, Stolle K, Schueller J, Boue S, Vuillaume G, Vanscheeuwijck P, Moehring M, Schlage W, De Leon H, Hoeng J, Peitsch M. Lietz M, et al. Among authors: vanscheeuwijck p. Atherosclerosis. 2013 Jul;229(1):86-93. doi: 10.1016/j.atherosclerosis.2013.03.036. Epub 2013 Apr 22. Atherosclerosis. 2013. PMID: 23669247 Free article.
Cigarette smoke induces molecular responses in respiratory tissues of ApoE(-/-) mice that are progressively deactivated upon cessation.
Boué S, De León H, Schlage WK, Peck MJ, Weiler H, Berges A, Vuillaume G, Martin F, Friedrichs B, Lebrun S, Meurrens K, Schracke N, Moehring M, Steffen Y, Schueller J, Vanscheeuwijck P, Peitsch MC, Hoeng J. Boué S, et al. Among authors: vanscheeuwijck p. Toxicology. 2013 Dec 6;314(1):112-24. doi: 10.1016/j.tox.2013.09.013. Epub 2013 Oct 1. Toxicology. 2013. PMID: 24096154 Free article.
A 28-day rat inhalation study with an integrated molecular toxicology endpoint demonstrates reduced exposure effects for a prototypic modified risk tobacco product compared with conventional cigarettes.
Kogel U, Schlage WK, Martin F, Xiang Y, Ansari S, Leroy P, Vanscheeuwijck P, Gebel S, Buettner A, Wyss C, Esposito M, Hoeng J, Peitsch MC. Kogel U, et al. Among authors: vanscheeuwijck p. Food Chem Toxicol. 2014 Jun;68:204-17. doi: 10.1016/j.fct.2014.02.034. Epub 2014 Mar 12. Food Chem Toxicol. 2014. PMID: 24632068 Free article.
Systems toxicology approaches enable mechanistic comparison of spontaneous and cigarette smoke-related lung tumor development in the A/J mouse model.
Luettich K, Xiang Y, Iskandar A, Sewer A, Martin F, Talikka M, Vanscheeuwijck P, Berges A, Veljkovic E, Gonzalez-Suarez I, Schlage W, Hoeng J, Peitsch M. Luettich K, et al. Among authors: vanscheeuwijck p. Interdiscip Toxicol. 2014 Jun;7(2):73-84. doi: 10.2478/intox-2014-0010. Epub 2014 Nov 15. Interdiscip Toxicol. 2014. PMID: 26109882 Free PMC article.
68 results