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MAP kinases and the control of nuclear events.
Turjanski AG, Vaqué JP, Gutkind JS. Turjanski AG, et al. Among authors: vaque jp. Oncogene. 2007 May 14;26(22):3240-53. doi: 10.1038/sj.onc.1210415. Oncogene. 2007. PMID: 17496919 Review.
p73 cooperates with Ras in the activation of MAP kinase signaling cascade.
Fernandez-Garcia B, Vaqué JP, Herreros-Villanueva M, Marques-Garcia F, Castrillo F, Fernandez-Medarde A, León J, Marín MC. Fernandez-Garcia B, et al. Among authors: vaque jp. Cell Death Differ. 2007 Feb;14(2):254-65. doi: 10.1038/sj.cdd.4401945. Epub 2006 Apr 28. Cell Death Differ. 2007. PMID: 16645632
Activation of Ras and Rho GTPases and MAP Kinases by G-protein-coupled receptors.
Chiariello M, Vaqué JP, Crespo P, Gutkind JS. Chiariello M, et al. Among authors: vaque jp. Methods Mol Biol. 2010;661:137-50. doi: 10.1007/978-1-60761-795-2_8. Methods Mol Biol. 2010. PMID: 20811981
A genome-wide RNAi screen reveals a Trio-regulated Rho GTPase circuitry transducing mitogenic signals initiated by G protein-coupled receptors.
Vaqué JP, Dorsam RT, Feng X, Iglesias-Bartolome R, Forsthoefel DJ, Chen Q, Debant A, Seeger MA, Ksander BR, Teramoto H, Gutkind JS. Vaqué JP, et al. Mol Cell. 2013 Jan 10;49(1):94-108. doi: 10.1016/j.molcel.2012.10.018. Epub 2012 Nov 21. Mol Cell. 2013. PMID: 23177739 Free PMC article.
Control of the differentiation of regulatory T cells and T(H)17 cells by the DNA-binding inhibitor Id3.
Maruyama T, Li J, Vaque JP, Konkel JE, Wang W, Zhang B, Zhang P, Zamarron BF, Yu D, Wu Y, Zhuang Y, Gutkind JS, Chen W. Maruyama T, et al. Among authors: vaque jp. Nat Immunol. 2011 Jan;12(1):86-95. doi: 10.1038/ni.1965. Epub 2010 Dec 5. Nat Immunol. 2011. PMID: 21131965 Free PMC article.
Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a trio-regulated rho GTPase signaling circuitry.
Feng X, Degese MS, Iglesias-Bartolome R, Vaque JP, Molinolo AA, Rodrigues M, Zaidi MR, Ksander BR, Merlino G, Sodhi A, Chen Q, Gutkind JS. Feng X, et al. Among authors: vaque jp. Cancer Cell. 2014 Jun 16;25(6):831-45. doi: 10.1016/j.ccr.2014.04.016. Epub 2014 May 29. Cancer Cell. 2014. PMID: 24882515 Free PMC article.
H-, K- and N-Ras inhibit myeloid leukemia cell proliferation by a p21WAF1-dependent mechanism.
Delgado MD, Vaqué JP, Arozarena I, López-Ilasaca MA, Martínez C, Crespo P, León J. Delgado MD, et al. Among authors: vaque jp. Oncogene. 2000 Feb 10;19(6):783-90. doi: 10.1038/sj.onc.1203384. Oncogene. 2000. PMID: 10698496
MYC antagonizes the differentiation induced by imatinib in chronic myeloid leukemia cells through downregulation of p27(KIP1.).
Gómez-Casares MT, García-Alegria E, López-Jorge CE, Ferrándiz N, Blanco R, Alvarez S, Vaqué JP, Bretones G, Caraballo JM, Sánchez-Bailón P, Delgado MD, Martín-Perez J, Cigudosa JC, León J. Gómez-Casares MT, et al. Among authors: vaque jp. Oncogene. 2013 Apr 25;32(17):2239-46. doi: 10.1038/onc.2012.246. Epub 2012 Jun 18. Oncogene. 2013. PMID: 22710719
c-Myc inhibits Ras-mediated differentiation of pheochromocytoma cells by blocking c-Jun up-regulation.
Vaqué JP, Fernández-García B, García-Sanz P, Ferrandiz N, Bretones G, Calvo F, Crespo P, Marín MC, León J. Vaqué JP, et al. Mol Cancer Res. 2008 Feb;6(2):325-39. doi: 10.1158/1541-7786.MCR-07-0180. Mol Cancer Res. 2008. PMID: 18314492
Myc antagonizes Ras-mediated growth arrest in leukemia cells through the inhibition of the Ras-ERK-p21Cip1 pathway.
Vaqué JP, Navascues J, Shiio Y, Laiho M, Ajenjo N, Mauleon I, Matallanas D, Crespo P, León J. Vaqué JP, et al. J Biol Chem. 2005 Jan 14;280(2):1112-22. doi: 10.1074/jbc.M409503200. Epub 2004 Nov 4. J Biol Chem. 2005. PMID: 15528212
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