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239 results
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Loss of RUNX3 expression is an independent adverse prognostic factor in diffuse large B-cell lymphoma.
Duncan VE, Ping Z, Varambally S, Peker D. Duncan VE, et al. Among authors: varambally s. Leuk Lymphoma. 2017 Jan;58(1):179-184. doi: 10.1080/10428194.2016.1180686. Epub 2016 May 17. Leuk Lymphoma. 2017. PMID: 27184221
EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells.
Kleer CG, Cao Q, Varambally S, Shen R, Ota I, Tomlins SA, Ghosh D, Sewalt RG, Otte AP, Hayes DF, Sabel MS, Livant D, Weiss SJ, Rubin MA, Chinnaiyan AM. Kleer CG, et al. Among authors: varambally s. Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11606-11. doi: 10.1073/pnas.1933744100. Epub 2003 Sep 19. Proc Natl Acad Sci U S A. 2003. PMID: 14500907 Free PMC article.
The Polycomb group protein EZH2 impairs DNA repair in breast epithelial cells.
Zeidler M, Varambally S, Cao Q, Chinnaiyan AM, Ferguson DO, Merajver SD, Kleer CG. Zeidler M, et al. Among authors: varambally s. Neoplasia. 2005 Nov;7(11):1011-9. doi: 10.1593/neo.05472. Neoplasia. 2005. PMID: 16331887 Free PMC article.
Identification of GATA3 as a breast cancer prognostic marker by global gene expression meta-analysis.
Mehra R, Varambally S, Ding L, Shen R, Sabel MS, Ghosh D, Chinnaiyan AM, Kleer CG. Mehra R, et al. Among authors: varambally s. Cancer Res. 2005 Dec 15;65(24):11259-64. doi: 10.1158/0008-5472.CAN-05-2495. Cancer Res. 2005. PMID: 16357129
Integrative genomics analysis reveals silencing of beta-adrenergic signaling by polycomb in prostate cancer.
Yu J, Cao Q, Mehra R, Laxman B, Yu J, Tomlins SA, Creighton CJ, Dhanasekaran SM, Shen R, Chen G, Morris DS, Marquez VE, Shah RB, Ghosh D, Varambally S, Chinnaiyan AM. Yu J, et al. Among authors: varambally s. Cancer Cell. 2007 Nov;12(5):419-31. doi: 10.1016/j.ccr.2007.10.016. Cancer Cell. 2007. PMID: 17996646
A polycomb repression signature in metastatic prostate cancer predicts cancer outcome.
Yu J, Yu J, Rhodes DR, Tomlins SA, Cao X, Chen G, Mehra R, Wang X, Ghosh D, Shah RB, Varambally S, Pienta KJ, Chinnaiyan AM. Yu J, et al. Among authors: varambally s. Cancer Res. 2007 Nov 15;67(22):10657-63. doi: 10.1158/0008-5472.CAN-07-2498. Cancer Res. 2007. PMID: 18006806
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer.
Varambally S, Cao Q, Mani RS, Shankar S, Wang X, Ateeq B, Laxman B, Cao X, Jing X, Ramnarayanan K, Brenner JC, Yu J, Kim JH, Han B, Tan P, Kumar-Sinha C, Lonigro RJ, Palanisamy N, Maher CA, Chinnaiyan AM. Varambally S, et al. Science. 2008 Dec 12;322(5908):1695-9. doi: 10.1126/science.1165395. Epub 2008 Nov 13. Science. 2008. PMID: 19008416 Free PMC article.
An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression.
Yu J, Yu J, Mani RS, Cao Q, Brenner CJ, Cao X, Wang X, Wu L, Li J, Hu M, Gong Y, Cheng H, Laxman B, Vellaichamy A, Shankar S, Li Y, Dhanasekaran SM, Morey R, Barrette T, Lonigro RJ, Tomlins SA, Varambally S, Qin ZS, Chinnaiyan AM. Yu J, et al. Among authors: varambally s. Cancer Cell. 2010 May 18;17(5):443-54. doi: 10.1016/j.ccr.2010.03.018. Cancer Cell. 2010. PMID: 20478527 Free PMC article.
Characterization of the EZH2-MMSET histone methyltransferase regulatory axis in cancer.
Asangani IA, Ateeq B, Cao Q, Dodson L, Pandhi M, Kunju LP, Mehra R, Lonigro RJ, Siddiqui J, Palanisamy N, Wu YM, Cao X, Kim JH, Zhao M, Qin ZS, Iyer MK, Maher CA, Kumar-Sinha C, Varambally S, Chinnaiyan AM. Asangani IA, et al. Among authors: varambally s. Mol Cell. 2013 Jan 10;49(1):80-93. doi: 10.1016/j.molcel.2012.10.008. Epub 2012 Nov 15. Mol Cell. 2013. PMID: 23159737 Free PMC article.
Role and regulation of coordinately expressed de novo purine biosynthetic enzymes PPAT and PAICS in lung cancer.
Goswami MT, Chen G, Chakravarthi BV, Pathi SS, Anand SK, Carskadon SL, Giordano TJ, Chinnaiyan AM, Thomas DG, Palanisamy N, Beer DG, Varambally S. Goswami MT, et al. Among authors: varambally s. Oncotarget. 2015 Sep 15;6(27):23445-61. doi: 10.18632/oncotarget.4352. Oncotarget. 2015. PMID: 26140362 Free PMC article.
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