Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.


The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page


My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 1
1981 1
1985 2
1988 1
1990 2
1993 1
1995 2
1996 2
1997 4
1998 2
1999 7
2000 4
2001 5
2003 1
2004 1
2005 2
2006 3
2007 4
2008 4
2009 8
2010 9
2011 16
2012 14
2013 11
2014 13
2015 8
2016 19
2017 17
2018 20
2019 7
2020 16
2021 33
2022 21
2023 16
2024 11

Text availability

Article attribute

Article type

Publication date

Search Results

263 results

Results by year

Filters applied: . Clear all
Page 1
GLP-1 Receptor Signaling in Astrocytes Regulates Fatty Acid Oxidation, Mitochondrial Integrity, and Function.
Timper K, Del Río-Martín A, Cremer AL, Bremser S, Alber J, Giavalisco P, Varela L, Heilinger C, Nolte H, Trifunovic A, Horvath TL, Kloppenburg P, Backes H, Brüning JC. Timper K, et al. Among authors: varela l. Cell Metab. 2020 Jun 2;31(6):1189-1205.e13. doi: 10.1016/j.cmet.2020.05.001. Epub 2020 May 19. Cell Metab. 2020. PMID: 32433922 Free PMC article.
Hepatocyte-specific suppression of ANGPTL4 improves obesity-associated diabetes and mitigates atherosclerosis in mice.
Singh AK, Chaube B, Zhang X, Sun J, Citrin KM, Canfrán-Duque A, Aryal B, Rotllan N, Varela L, Lee RG, Horvath TL, Price N, Suárez Y, Fernandez-Hernando C. Singh AK, et al. Among authors: varela l. J Clin Invest. 2021 Jul 13;131(17):e140989. doi: 10.1172/JCI140989. Online ahead of print. J Clin Invest. 2021. PMID: 34255741 Free PMC article.
CerS6-dependent ceramide synthesis in hypothalamic neurons promotes ER/mitochondrial stress and impairs glucose homeostasis in obese mice.
Hammerschmidt P, Steculorum SM, Bandet CL, Del Río-Martín A, Steuernagel L, Kohlhaas V, Feldmann M, Varela L, Majcher A, Quatorze Correia M, Klar RFU, Bauder CA, Kaya E, Porniece M, Biglari N, Sieben A, Horvath TL, Hornemann T, Brodesser S, Brüning JC. Hammerschmidt P, et al. Among authors: varela l. Nat Commun. 2023 Nov 29;14(1):7824. doi: 10.1038/s41467-023-42595-7. Nat Commun. 2023. PMID: 38016943 Free PMC article.
Oncogenic Pathways in Neurodegenerative Diseases.
Varela L, Garcia-Rendueles MER. Varela L, et al. Int J Mol Sci. 2022 Mar 17;23(6):3223. doi: 10.3390/ijms23063223. Int J Mol Sci. 2022. PMID: 35328644 Free PMC article. Review.
Mitochondrial cristae-remodeling protein OPA1 in POMC neurons couples Ca2+ homeostasis with adipose tissue lipolysis.
Gómez-Valadés AG, Pozo M, Varela L, Boudjadja MB, Ramírez S, Chivite I, Eyre E, Haddad-Tóvolli R, Obri A, Milà-Guasch M, Altirriba J, Schneeberger M, Imbernón M, Garcia-Rendueles AR, Gama-Perez P, Rojo-Ruiz J, Rácz B, Alonso MT, Gomis R, Zorzano A, D'Agostino G, Alvarez CV, Nogueiras R, Garcia-Roves PM, Horvath TL, Claret M. Gómez-Valadés AG, et al. Among authors: varela l. Cell Metab. 2021 Sep 7;33(9):1820-1835.e9. doi: 10.1016/j.cmet.2021.07.008. Epub 2021 Aug 2. Cell Metab. 2021. PMID: 34343501 Free PMC article.
Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability.
García-Cáceres C, Quarta C, Varela L, Gao Y, Gruber T, Legutko B, Jastroch M, Johansson P, Ninkovic J, Yi CX, Le Thuc O, Szigeti-Buck K, Cai W, Meyer CW, Pfluger PT, Fernandez AM, Luquet S, Woods SC, Torres-Alemán I, Kahn CR, Götz M, Horvath TL, Tschöp MH. García-Cáceres C, et al. Among authors: varela l. Cell. 2016 Aug 11;166(4):867-880. doi: 10.1016/j.cell.2016.07.028. Cell. 2016. PMID: 27518562 Free PMC article.
Hypothalamic lipotoxicity and the metabolic syndrome.
Martínez de Morentin PB, Varela L, Fernø J, Nogueiras R, Diéguez C, López M. Martínez de Morentin PB, et al. Among authors: varela l. Biochim Biophys Acta. 2010 Mar;1801(3):350-61. doi: 10.1016/j.bbalip.2009.09.016. Epub 2009 Sep 29. Biochim Biophys Acta. 2010. PMID: 19796707 Review.
263 results