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TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal.
Varelas X, Sakuma R, Samavarchi-Tehrani P, Peerani R, Rao BM, Dembowy J, Yaffe MB, Zandstra PW, Wrana JL. Varelas X, et al. Nat Cell Biol. 2008 Jul;10(7):837-48. doi: 10.1038/ncb1748. Epub 2008 Jun 22. Nat Cell Biol. 2008. PMID: 18568018
The Hippo pathway regulates Wnt/beta-catenin signaling.
Varelas X, Miller BW, Sopko R, Song S, Gregorieff A, Fellouse FA, Sakuma R, Pawson T, Hunziker W, McNeill H, Wrana JL, Attisano L. Varelas X, et al. Dev Cell. 2010 Apr 20;18(4):579-91. doi: 10.1016/j.devcel.2010.03.007. Dev Cell. 2010. PMID: 20412773
Integrating developmental signals: a Hippo in the (path)way.
Mauviel A, Nallet-Staub F, Varelas X. Mauviel A, et al. Oncogene. 2012 Apr 5;31(14):1743-56. doi: 10.1038/onc.2011.363. Epub 2011 Aug 29. Oncogene. 2012. PMID: 21874053 Review.
Coordinating developmental signaling: novel roles for the Hippo pathway.
Varelas X, Wrana JL. Varelas X, et al. Trends Cell Biol. 2012 Feb;22(2):88-96. doi: 10.1016/j.tcb.2011.10.002. Epub 2011 Dec 5. Trends Cell Biol. 2012. PMID: 22153608 Review.
Stem cell regulation by the Hippo pathway.
Hiemer SE, Varelas X. Hiemer SE, et al. Biochim Biophys Acta. 2013 Feb;1830(2):2323-34. doi: 10.1016/j.bbagen.2012.07.005. Epub 2012 Jul 20. Biochim Biophys Acta. 2013. PMID: 22824335 Review.
The transcriptional regulators TAZ and YAP direct transforming growth factor β-induced tumorigenic phenotypes in breast cancer cells.
Hiemer SE, Szymaniak AD, Varelas X. Hiemer SE, et al. J Biol Chem. 2014 May 9;289(19):13461-74. doi: 10.1074/jbc.M113.529115. Epub 2014 Mar 19. J Biol Chem. 2014. PMID: 24648515 Free PMC article.
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