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263 results

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Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer.
Vaishnavi A, Capelletti M, Le AT, Kako S, Butaney M, Ercan D, Mahale S, Davies KD, Aisner DL, Pilling AB, Berge EM, Kim J, Sasaki H, Park S, Kryukov G, Garraway LA, Hammerman PS, Haas J, Andrews SW, Lipson D, Stephens PJ, Miller VA, Varella-Garcia M, Jänne PA, Doebele RC. Vaishnavi A, et al. Nat Med. 2013 Nov;19(11):1469-1472. doi: 10.1038/nm.3352. Epub 2013 Oct 27. Nat Med. 2013. PMID: 24162815 Free PMC article.
Clinical benefit from pemetrexed before and after crizotinib exposure and from crizotinib before and after pemetrexed exposure in patients with anaplastic lymphoma kinase-positive non-small-cell lung cancer.
Berge EM, Lu X, Maxson D, Barón AE, Gadgeel SM, Solomon BJ, Doebele RC, Varella-Garcia M, Camidge DR. Berge EM, et al. Clin Lung Cancer. 2013 Nov;14(6):636-43. doi: 10.1016/j.cllc.2013.06.005. Epub 2013 Aug 6. Clin Lung Cancer. 2013. PMID: 23931899 Free PMC article.
XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer.
Morton JJ, Bird G, Keysar SB, Astling DP, Lyons TR, Anderson RT, Glogowska MJ, Estes P, Eagles JR, Le PN, Gan G, McGettigan B, Fernandez P, Padilla-Just N, Varella-Garcia M, Song JI, Bowles DW, Schedin P, Tan AC, Roop DR, Wang XJ, Refaeli Y, Jimeno A. Morton JJ, et al. Oncogene. 2016 Jan 21;35(3):290-300. doi: 10.1038/onc.2015.94. Epub 2015 Apr 20. Oncogene. 2016. PMID: 25893296 Free PMC article.
EYA2 tyrosine phosphatase inhibition reduces MYC and prevents medulloblastoma progression.
Wolin AR, Vincent MY, Hotz T, Purdy SC, Rosenbaum SR, Hughes CJ, Hsu JY, Oliphant MUJ, Armstrong B, Wessells V, Varella-Garcia M, Galbraith MD, Pierce A, Wang D, Venkataraman S, Danis E, Veo B, Serkova N, Espinosa JM, Gustafson DL, Vibhakar R, Ford HL. Wolin AR, et al. Among authors: varella garcia m. Neuro Oncol. 2023 Dec 8;25(12):2287-2301. doi: 10.1093/neuonc/noad128. Neuro Oncol. 2023. PMID: 37486991
NTRK2 gene fusions are uncommon in pilocytic astrocytoma.
Moreno DA, Becker AP, Scapulatempo-Neto C, Menezes W, Sheren J, Walter AM, Clara C, Machado HR, Oliveira RS, Neder L, Varella-Garcia M, Reis RM. Moreno DA, et al. Among authors: varella garcia m. Mol Biol Rep. 2022 Aug;49(8):7567-7573. doi: 10.1007/s11033-022-07567-y. Epub 2022 Jun 17. Mol Biol Rep. 2022. PMID: 35713800
EGFR High Copy Number Together With High EGFR Protein Expression Predicts Improved Outcome for Cetuximab-based Therapy in Squamous Cell Lung Cancer: Analysis From SWOG S0819, a Phase III Trial of Chemotherapy With or Without Cetuximab in Advanced NSCLC.
Hirsch FR, Redman MW, Moon J, Agustoni F, Herbst RS, Semrad TJ, Varella-Garcia M, Rivard CJ, Kelly K, Gandara DR, Mack PC. Hirsch FR, et al. Among authors: varella garcia m. Clin Lung Cancer. 2022 Jan;23(1):60-71. doi: 10.1016/j.cllc.2021.10.002. Epub 2021 Oct 10. Clin Lung Cancer. 2022. PMID: 34753703 Free PMC article. Clinical Trial.
The International Association for the Study of Lung Cancer Global Survey on Molecular Testing in Lung Cancer.
Smeltzer MP, Wynes MW, Lantuejoul S, Soo R, Ramalingam SS, Varella-Garcia M, Meadows Taylor M, Richeimer K, Wood K, Howell KE, Dalurzo ML, Felip E, Hollenbeck G, Kerr K, Kim ES, Mathias C, Pacheco J, Postmus P, Powell C, Tsuboi M, Wistuba II, Wakelee HA, Belani CP, Scagliotti GV, Hirsch FR. Smeltzer MP, et al. Among authors: varella garcia m. J Thorac Oncol. 2020 Sep;15(9):1434-1448. doi: 10.1016/j.jtho.2020.05.002. Epub 2020 May 20. J Thorac Oncol. 2020. PMID: 32445813 Free article.
Round Robin Evaluation of MET Protein Expression in Lung Adenocarcinomas Improves Interobserver Concordance.
Boyle TA, Khalil FK, Mino-Kenudson M, Sica GL, Moreira AL, Sholl LM, Knight MZ, Zhang L, Saller J, Varella-Garcia M, Berry LD, Chen H, Ellison KE, Rivard CJ, Kugler K, Wistuba II, Fujimoto J, Kwiatkowski DJ, Bunn PA, Kris MG, Haura EB, Hirsch FR; Lung Cancer Mutation Consortium (LCMC) Pathologist Panel Group. Boyle TA, et al. Among authors: varella garcia m. Appl Immunohistochem Mol Morphol. 2020 Oct;28(9):669-677. doi: 10.1097/PAI.0000000000000810. Appl Immunohistochem Mol Morphol. 2020. PMID: 31876606 Free PMC article.
263 results