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Tumor necrosis factor receptor and Fas signaling mechanisms.
Wallach D, Varfolomeev EE, Malinin NL, Goltsev YV, Kovalenko AV, Boldin MP. Wallach D, et al. Among authors: varfolomeev ee. Annu Rev Immunol. 1999;17:331-67. doi: 10.1146/annurev.immunol.17.1.331. Annu Rev Immunol. 1999. PMID: 10358762 Review.
How are the regulators regulated? The search for mechanisms that impose specificity on induction of cell death and NF-kappaB activation by members of the TNF/NGF receptor family.
Wallach D, Arumugam TU, Boldin MP, Cantarella G, Ganesh KA, Goltsev Y, Goncharov TM, Kovalenko AV, Rajput A, Varfolomeev EE, Zhang SQ. Wallach D, et al. Among authors: varfolomeev ee. Arthritis Res. 2002;4 Suppl 3(Suppl 3):S189-96. doi: 10.1186/ar585. Epub 2002 May 9. Arthritis Res. 2002. PMID: 12110139 Free PMC article. Review.
Caspase-8 serves both apoptotic and nonapoptotic roles.
Kang TB, Ben-Moshe T, Varfolomeev EE, Pewzner-Jung Y, Yogev N, Jurewicz A, Waisman A, Brenner O, Haffner R, Gustafsson E, Ramakrishnan P, Lapidot T, Wallach D. Kang TB, et al. Among authors: varfolomeev ee. J Immunol. 2004 Sep 1;173(5):2976-84. doi: 10.4049/jimmunol.173.5.2976. J Immunol. 2004. PMID: 15322156 Free article.
Tumor necrosis factor: an apoptosis JuNKie?
Varfolomeev EE, Ashkenazi A. Varfolomeev EE, et al. Cell. 2004 Feb 20;116(4):491-7. doi: 10.1016/s0092-8674(04)00166-7. Cell. 2004. PMID: 14980217 Free article. Review.
Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.
Varfolomeev EE, Schuchmann M, Luria V, Chiannilkulchai N, Beckmann JS, Mett IL, Rebrikov D, Brodianski VM, Kemper OC, Kollet O, Lapidot T, Soffer D, Sobe T, Avraham KB, Goncharov T, Holtmann H, Lonai P, Wallach D. Varfolomeev EE, et al. Immunity. 1998 Aug;9(2):267-76. doi: 10.1016/s1074-7613(00)80609-3. Immunity. 1998. PMID: 9729047 Free article.
CASH, a novel caspase homologue with death effector domains.
Goltsev YV, Kovalenko AV, Arnold E, Varfolomeev EE, Brodianskii VM, Wallach D. Goltsev YV, et al. Among authors: varfolomeev ee. J Biol Chem. 1997 Aug 8;272(32):19641-4. doi: 10.1074/jbc.272.32.19641. J Biol Chem. 1997. PMID: 9289491 Free article.
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