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Smad-independent transforming growth factor-beta regulation of early growth response-1 and sustained expression in fibrosis: implications for scleroderma.
Bhattacharyya S, Chen SJ, Wu M, Warner-Blankenship M, Ning H, Lakos G, Mori Y, Chang E, Nihijima C, Takehara K, Feghali-Bostwick C, Varga J. Bhattacharyya S, et al. Among authors: varga j. Am J Pathol. 2008 Oct;173(4):1085-99. doi: 10.2353/ajpath.2008.080382. Epub 2008 Sep 4. Am J Pathol. 2008. PMID: 18772333 Free PMC article.
The early growth response gene Egr2 (Alias Krox20) is a novel transcriptional target of transforming growth factor-β that is up-regulated in systemic sclerosis and mediates profibrotic responses.
Fang F, Ooka K, Bhattacharyya S, Wei J, Wu M, Du P, Lin S, Del Galdo F, Feghali-Bostwick CA, Varga J. Fang F, et al. Among authors: varga j. Am J Pathol. 2011 May;178(5):2077-90. doi: 10.1016/j.ajpath.2011.01.035. Am J Pathol. 2011. PMID: 21514423 Free PMC article.
Toll-like receptor 4 signaling augments transforming growth factor-β responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma.
Bhattacharyya S, Kelley K, Melichian DS, Tamaki Z, Fang F, Su Y, Feng G, Pope RM, Budinger GR, Mutlu GM, Lafyatis R, Radstake T, Feghali-Bostwick C, Varga J. Bhattacharyya S, et al. Among authors: varga j. Am J Pathol. 2013 Jan;182(1):192-205. doi: 10.1016/j.ajpath.2012.09.007. Epub 2012 Nov 7. Am J Pathol. 2013. PMID: 23141927 Free PMC article.
Identification of Optimal Mouse Models of Systemic Sclerosis by Interspecies Comparative Genomics.
Sargent JL, Li Z, Aliprantis AO, Greenblatt M, Lemaire R, Wu MH, Wei J, Taroni J, Harris A, Long KB, Burgwin C, Artlett CM, Blankenhorn EP, Lafyatis R, Varga J, Clark SH, Whitfield ML. Sargent JL, et al. Among authors: varga j. Arthritis Rheumatol. 2016 Aug;68(8):2003-15. doi: 10.1002/art.39658. Arthritis Rheumatol. 2016. PMID: 26945694 Free PMC article.
1,224 results