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Endosomal escape pathways for delivery of biologicals.
Varkouhi AK, Scholte M, Storm G, Haisma HJ. Varkouhi AK, et al. J Control Release. 2011 May 10;151(3):220-8. doi: 10.1016/j.jconrel.2010.11.004. Epub 2010 Nov 13. J Control Release. 2011. PMID: 21078351 Review.
Comparison of polymeric siRNA nanocarriers in a murine LPS-activated macrophage cell line: gene silencing, toxicity and off-target gene expression.
Jensen LB, Griger J, Naeye B, Varkouhi AK, Raemdonck K, Schiffelers R, Lammers T, Storm G, de Smedt SC, Sproat BS, Nielsen HM, Foged C. Jensen LB, et al. Among authors: varkouhi ak. Pharm Res. 2012 Mar;29(3):669-82. doi: 10.1007/s11095-011-0589-0. Epub 2011 Oct 5. Pharm Res. 2012. PMID: 21971827
Polyplexes based on cationic polymers with strong nucleic acid binding properties.
Varkouhi AK, Mountrichas G, Schiffelers RM, Lammers T, Storm G, Pispas S, Hennink WE. Varkouhi AK, et al. Eur J Pharm Sci. 2012 Mar 12;45(4):459-66. doi: 10.1016/j.ejps.2011.09.002. Epub 2011 Sep 8. Eur J Pharm Sci. 2012. PMID: 21925599
Gene silencing activity of siRNA polyplexes based on biodegradable polymers.
Varkouhi AK, Lammers T, Schiffelers RM, van Steenbergen MJ, Hennink WE, Storm G. Varkouhi AK, et al. Eur J Pharm Biopharm. 2011 Apr;77(3):450-7. doi: 10.1016/j.ejpb.2010.11.016. Epub 2010 Nov 29. Eur J Pharm Biopharm. 2011. PMID: 21118719
Core-crosslinked polymeric micelles with controlled release of covalently entrapped doxorubicin.
Talelli M, Iman M, Varkouhi AK, Rijcken CJ, Schiffelers RM, Etrych T, Ulbrich K, van Nostrum CF, Lammers T, Storm G, Hennink WE. Talelli M, et al. Biomaterials. 2010 Oct;31(30):7797-804. doi: 10.1016/j.biomaterials.2010.07.005. Epub 2010 Jul 31. Biomaterials. 2010. PMID: 20673684
Gene silencing activity of siRNA polyplexes based on thiolated N,N,N-trimethylated chitosan.
Varkouhi AK, Verheul RJ, Schiffelers RM, Lammers T, Storm G, Hennink WE. Varkouhi AK, et al. Bioconjug Chem. 2010 Dec 15;21(12):2339-46. doi: 10.1021/bc1003789. Epub 2010 Nov 4. Bioconjug Chem. 2010. PMID: 21049986
MRI-assessed therapeutic effects of locally administered PLGA nanoparticles loaded with anti-inflammatory siRNA in a murine arthritis model.
te Boekhorst BC, Jensen LB, Colombo S, Varkouhi AK, Schiffelers RM, Lammers T, Storm G, Nielsen HM, Strijkers GJ, Foged C, Nicolay K. te Boekhorst BC, et al. Among authors: varkouhi ak. J Control Release. 2012 Aug 10;161(3):772-80. doi: 10.1016/j.jconrel.2012.05.004. Epub 2012 May 11. J Control Release. 2012. PMID: 22580113
SiRNA delivery with functionalized carbon nanotubes.
Varkouhi AK, Foillard S, Lammers T, Schiffelers RM, Doris E, Hennink WE, Storm G. Varkouhi AK, et al. Int J Pharm. 2011 Sep 20;416(2):419-25. doi: 10.1016/j.ijpharm.2011.02.009. Epub 2011 Feb 12. Int J Pharm. 2011. PMID: 21320582
Photochemical internalization (PCI)-mediated enhancement of gene silencing efficiency of polymethacrylates and N,N,N-trimethylated chitosan (TMC) based siRNA polyplexes.
Varkouhi AK, Schiffelers RM, van Steenbergen MJ, Lammers T, Hennink WE, Storm G. Varkouhi AK, et al. J Control Release. 2010 Nov 20;148(1):e98-9. doi: 10.1016/j.jconrel.2010.07.072. J Control Release. 2010. PMID: 21529659 No abstract available.
Genetically Modified Mesenchymal Stromal/Stem Cells: Application in Critical Illness.
Varkouhi AK, Monteiro APT, Tsoporis JN, Mei SHJ, Stewart DJ, Dos Santos CC. Varkouhi AK, et al. Stem Cell Rev Rep. 2020 Jul 15:1-16. doi: 10.1007/s12015-020-10000-1. Online ahead of print. Stem Cell Rev Rep. 2020. PMID: 32671645 Free PMC article. Review.
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