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Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance.
Gillet JP, Calcagno AM, Varma S, Marino M, Green LJ, Vora MI, Patel C, Orina JN, Eliseeva TA, Singal V, Padmanabhan R, Davidson B, Ganapathi R, Sood AK, Rueda BR, Ambudkar SV, Gottesman MM. Gillet JP, et al. Among authors: varma s. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18708-13. doi: 10.1073/pnas.1111840108. Epub 2011 Nov 8. Proc Natl Acad Sci U S A. 2011. PMID: 22068913 Free PMC article.
Evaluation of current methods used to analyze the expression profiles of ATP-binding cassette transporters yields an improved drug-discovery database.
Orina JN, Calcagno AM, Wu CP, Varma S, Shih J, Lin M, Eichler G, Weinstein JN, Pommier Y, Ambudkar SV, Gottesman MM, Gillet JP. Orina JN, et al. Among authors: varma s. Mol Cancer Ther. 2009 Jul;8(7):2057-66. doi: 10.1158/1535-7163.MCT-09-0256. Epub 2009 Jul 7. Mol Cancer Ther. 2009. PMID: 19584229 Free PMC article.
Multidrug resistance-linked gene signature predicts overall survival of patients with primary ovarian serous carcinoma.
Gillet JP, Calcagno AM, Varma S, Davidson B, Bunkholt Elstrand M, Ganapathi R, Kamat AA, Sood AK, Ambudkar SV, Seiden MV, Rueda BR, Gottesman MM. Gillet JP, et al. Among authors: varma s. Clin Cancer Res. 2012 Jun 1;18(11):3197-206. doi: 10.1158/1078-0432.CCR-12-0056. Epub 2012 Apr 5. Clin Cancer Res. 2012. PMID: 22492981 Free PMC article.
The clinical relevance of cancer cell lines.
Gillet JP, Varma S, Gottesman MM. Gillet JP, et al. Among authors: varma s. J Natl Cancer Inst. 2013 Apr 3;105(7):452-8. doi: 10.1093/jnci/djt007. Epub 2013 Feb 21. J Natl Cancer Inst. 2013. PMID: 23434901 Free PMC article.
A Gene Expression Signature Associated with Overall Survival in Patients with Hepatocellular Carcinoma Suggests a New Treatment Strategy.
Gillet JP, Andersen JB, Madigan JP, Varma S, Bagni RK, Powell K, Burgan WE, Wu CP, Calcagno AM, Ambudkar SV, Thorgeirsson SS, Gottesman MM. Gillet JP, et al. Among authors: varma s. Mol Pharmacol. 2016 Feb;89(2):263-72. doi: 10.1124/mol.115.101360. Epub 2015 Dec 14. Mol Pharmacol. 2016. PMID: 26668215 Free PMC article.
1,750 results