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Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study.
Varma VR, Oommen AM, Varma S, Casanova R, An Y, Andrews RM, O'Brien R, Pletnikova O, Troncoso JC, Toledo J, Baillie R, Arnold M, Kastenmueller G, Nho K, Doraiswamy PM, Saykin AJ, Kaddurah-Daouk R, Legido-Quigley C, Thambisetty M. Varma VR, et al. Among authors: varma s. PLoS Med. 2018 Jan 25;15(1):e1002482. doi: 10.1371/journal.pmed.1002482. eCollection 2018 Jan. PLoS Med. 2018. PMID: 29370177 Free PMC article.
Alpha-2 macroglobulin in Alzheimer's disease: a marker of neuronal injury through the RCAN1 pathway.
Varma VR, Varma S, An Y, Hohman TJ, Seddighi S, Casanova R, Beri A, Dammer EB, Seyfried NT, Pletnikova O, Moghekar A, Wilson MR, Lah JJ, O'Brien RJ, Levey AI, Troncoso JC, Albert MS, Thambisetty M. Varma VR, et al. Among authors: varma s. Mol Psychiatry. 2017 Jan;22(1):13-23. doi: 10.1038/mp.2016.206. Epub 2016 Nov 22. Mol Psychiatry. 2017. PMID: 27872486 Free PMC article.
Evidence for brain glucose dysregulation in Alzheimer's disease.
An Y, Varma VR, Varma S, Casanova R, Dammer E, Pletnikova O, Chia CW, Egan JM, Ferrucci L, Troncoso J, Levey AI, Lah J, Seyfried NT, Legido-Quigley C, O'Brien R, Thambisetty M. An Y, et al. Among authors: varma s, varma vr. Alzheimers Dement. 2018 Mar;14(3):318-329. doi: 10.1016/j.jalz.2017.09.011. Epub 2017 Oct 19. Alzheimers Dement. 2018. PMID: 29055815 Free PMC article.
Dysregulation of multiple metabolic networks related to brain transmethylation and polyamine pathways in Alzheimer disease: A targeted metabolomic and transcriptomic study.
Mahajan UV, Varma VR, Griswold ME, Blackshear CT, An Y, Oommen AM, Varma S, Troncoso JC, Pletnikova O, O'Brien R, Hohman TJ, Legido-Quigley C, Thambisetty M. Mahajan UV, et al. Among authors: varma s, varma vr. PLoS Med. 2020 Jan 24;17(1):e1003012. doi: 10.1371/journal.pmed.1003012. eCollection 2020 Jan. PLoS Med. 2020. PMID: 31978055 Free PMC article.
Blood Metabolite Signature of Metabolic Syndrome Implicates Alterations in Amino Acid Metabolism: Findings from the Baltimore Longitudinal Study of Aging (BLSA) and the Tsuruoka Metabolomics Cohort Study (TMCS).
Roberts JA, Varma VR, Huang CW, An Y, Oommen A, Tanaka T, Ferrucci L, Elango P, Takebayashi T, Harada S, Iida M, Thambisetty M. Roberts JA, et al. Among authors: varma vr. Int J Mol Sci. 2020 Feb 13;21(4):1249. doi: 10.3390/ijms21041249. Int J Mol Sci. 2020. PMID: 32070008 Free PMC article.
53 results