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Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos.
He X, Saint-Jeannet JP, Woodgett JR, Varmus HE, Dawid IB. He X, et al. Nature. 1995 Apr 13;374(6523):617-22. doi: 10.1038/374617a0. Nature. 1995. PMID: 7715701
A member of the Frizzled protein family mediating axis induction by Wnt-5A.
He X, Saint-Jeannet JP, Wang Y, Nathans J, Dawid I, Varmus H. He X, et al. Science. 1997 Mar 14;275(5306):1652-4. doi: 10.1126/science.275.5306.1652. Science. 1997. PMID: 9054360
The National Institutes of Health and clinical research: a progress report.
Nathan DG, Varmus HE. Nathan DG, et al. Nat Med. 2000 Nov;6(11):1201-4. doi: 10.1038/81282. Nat Med. 2000. PMID: 11062519 No abstract available.
The knockout mouse project.
Austin CP, Battey JF, Bradley A, Bucan M, Capecchi M, Collins FS, Dove WF, Duyk G, Dymecki S, Eppig JT, Grieder FB, Heintz N, Hicks G, Insel TR, Joyner A, Koller BH, Lloyd KC, Magnuson T, Moore MW, Nagy A, Pollock JD, Roses AD, Sands AT, Seed B, Skarnes WC, Snoddy J, Soriano P, Stewart DJ, Stewart F, Stillman B, Varmus H, Varticovski L, Verma IM, Vogt TF, von Melchner H, Witkowski J, Woychik RP, Wurst W, Yancopoulos GD, Young SG, Zambrowicz B. Austin CP, et al. Nat Genet. 2004 Sep;36(9):921-4. doi: 10.1038/ng0904-921. Nat Genet. 2004. PMID: 15340423 Free PMC article.
Science funding: Provocative questions in cancer research.
Varmus H, Harlow E. Varmus H, et al. Nature. 2012 Jan 25;481(7382):436-7. doi: 10.1038/481436a. Nature. 2012. PMID: 22281578 No abstract available.
Characterizing the cancer genome in lung adenocarcinoma.
Weir BA, Woo MS, Getz G, Perner S, Ding L, Beroukhim R, Lin WM, Province MA, Kraja A, Johnson LA, Shah K, Sato M, Thomas RK, Barletta JA, Borecki IB, Broderick S, Chang AC, Chiang DY, Chirieac LR, Cho J, Fujii Y, Gazdar AF, Giordano T, Greulich H, Hanna M, Johnson BE, Kris MG, Lash A, Lin L, Lindeman N, Mardis ER, McPherson JD, Minna JD, Morgan MB, Nadel M, Orringer MB, Osborne JR, Ozenberger B, Ramos AH, Robinson J, Roth JA, Rusch V, Sasaki H, Shepherd F, Sougnez C, Spitz MR, Tsao MS, Twomey D, Verhaak RG, Weinstock GM, Wheeler DA, Winckler W, Yoshizawa A, Yu S, Zakowski MF, Zhang Q, Beer DG, Wistuba II, Watson MA, Garraway LA, Ladanyi M, Travis WD, Pao W, Rubin MA, Gabriel SB, Gibbs RA, Varmus HE, Wilson RK, Lander ES, Meyerson M. Weir BA, et al. Nature. 2007 Dec 6;450(7171):893-8. doi: 10.1038/nature06358. Epub 2007 Nov 4. Nature. 2007. PMID: 17982442 Free PMC article.
Defining the steps in a multistep mouse model for mammary carcinogenesis.
Varmus HE, Godley LA, Roy S, Taylor IC, Yuschenkoff L, Shi YP, Pinkel D, Gray J, Pyle R, Aldaz CM, et al. Varmus HE, et al. Cold Spring Harb Symp Quant Biol. 1994;59:491-9. doi: 10.1101/sqb.1994.059.01.054. Cold Spring Harb Symp Quant Biol. 1994. PMID: 7587104 Review. No abstract available.
A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice.
Holland EC, Hively WP, DePinho RA, Varmus HE. Holland EC, et al. Genes Dev. 1998 Dec 1;12(23):3675-85. doi: 10.1101/gad.12.23.3675. Genes Dev. 1998. PMID: 9851974 Free PMC article.
Modeling mutations in the G1 arrest pathway in human gliomas: overexpression of CDK4 but not loss of INK4a-ARF induces hyperploidy in cultured mouse astrocytes.
Holland EC, Hively WP, Gallo V, Varmus HE. Holland EC, et al. Genes Dev. 1998 Dec 1;12(23):3644-9. doi: 10.1101/gad.12.23.3644. Genes Dev. 1998. PMID: 9851971 Free PMC article.
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