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Therapeutic potential of breakers of advanced glycation end product-protein crosslinks.
Vasan S, Foiles P, Founds H. Vasan S, et al. Arch Biochem Biophys. 2003 Nov 1;419(1):89-96. doi: 10.1016/ Arch Biochem Biophys. 2003. PMID: 14568012 Review.
A cross-link breaker has sustained effects on arterial and ventricular properties in older rhesus monkeys.
Vaitkevicius PV, Lane M, Spurgeon H, Ingram DK, Roth GS, Egan JJ, Vasan S, Wagle DR, Ulrich P, Brines M, Wuerth JP, Cerami A, Lakatta EG. Vaitkevicius PV, et al. Among authors: vasan s. Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):1171-5. doi: 10.1073/pnas.98.3.1171. Proc Natl Acad Sci U S A. 2001. PMID: 11158613 Free PMC article.
An advanced glycation endproduct cross-link breaker can reverse age-related increases in myocardial stiffness.
Asif M, Egan J, Vasan S, Jyothirmayi GN, Masurekar MR, Lopez S, Williams C, Torres RL, Wagle D, Ulrich P, Cerami A, Brines M, Regan TJ. Asif M, et al. Among authors: vasan s. Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2809-13. doi: 10.1073/pnas.040558497. Proc Natl Acad Sci U S A. 2000. PMID: 10706607 Free PMC article.
Breakers of advanced glycation end products restore large artery properties in experimental diabetes.
Wolffenbuttel BH, Boulanger CM, Crijns FR, Huijberts MS, Poitevin P, Swennen GN, Vasan S, Egan JJ, Ulrich P, Cerami A, Lévy BI. Wolffenbuttel BH, et al. Among authors: vasan s. Proc Natl Acad Sci U S A. 1998 Apr 14;95(8):4630-4. doi: 10.1073/pnas.95.8.4630. Proc Natl Acad Sci U S A. 1998. PMID: 9539789 Free PMC article.
An agent cleaving glucose-derived protein crosslinks in vitro and in vivo.
Vasan S, Zhang X, Zhang X, Kapurniotu A, Bernhagen J, Teichberg S, Basgen J, Wagle D, Shih D, Terlecky I, Bucala R, Cerami A, Egan J, Ulrich P. Vasan S, et al. Nature. 1996 Jul 18;382(6588):275-8. doi: 10.1038/382275a0. Nature. 1996. PMID: 8717046
Advanced glycation has also been implicated in the pathology of Alzheimer's disease. Because AGEs may form by a pathway involving reactive alpha-dicarbonyl intermediates, we investigated a potential pharmacological strategy for selectively cleaving the resultant glucose-de …
Advanced glycation has also been implicated in the pathology of Alzheimer's disease. Because AGEs may form by a pathway involving rea …
Therapeutic potential of AGE inhibitors and breakers of AGE protein cross-links.
Vasan S, Foiles PG, Founds HW. Vasan S, et al. Expert Opin Investig Drugs. 2001 Nov;10(11):1977-87. doi: 10.1517/13543784.10.11.1977. Expert Opin Investig Drugs. 2001. PMID: 11772301 Review.
Renoprotective effects of a novel inhibitor of advanced glycation.
Forbes JM, Soulis T, Thallas V, Panagiotopoulos S, Long DM, Vasan S, Wagle D, Jerums G, Cooper ME. Forbes JM, et al. Among authors: vasan s. Diabetologia. 2001 Jan;44(1):108-14. doi: 10.1007/s001250051587. Diabetologia. 2001. PMID: 11206401
Prevalence, incidence and predictors of cardiovascular risk factors: longitudinal data from rural and urban South India and comparison with global data.
Vasan SK, Antonisamy B, Gowri M, Selliah HY, Geethanjali FS, Jebasingh FS, Paul TV, Thomas N, Karpe F, Johnson M, Osmond C, Fall CHD. Vasan SK, et al. BMJ Open Diabetes Res Care. 2020 Oct;8(1):e001782. doi: 10.1136/bmjdrc-2020-001782. BMJ Open Diabetes Res Care. 2020. PMID: 33093130
Experimental and in silico evidence suggests vaccines are unlikely to be affected by D614G mutation in SARS-CoV-2 spike protein.
McAuley AJ, Kuiper MJ, Durr PA, Bruce MP, Barr J, Todd S, Au GG, Blasdell K, Tachedjian M, Lowther S, Marsh GA, Edwards S, Poole T, Layton R, Riddell SJ, Drew TW, Druce JD, Smith TRF, Broderick KE, Vasan SS. McAuley AJ, et al. Among authors: vasan ss. NPJ Vaccines. 2020 Oct 8;5:96. doi: 10.1038/s41541-020-00246-8. eCollection 2020. NPJ Vaccines. 2020. PMID: 33083031 Free PMC article.
IgG3 collaborates with IgG1 and IgA to recruit effector function in RV144 vaccinees.
Fischinger S, Dolatshahi S, Jennewein MF, Rerks-Ngarm S, Pitisuttithum P, Nitayaphan S, Michael NL, Vasan S, Ackerman ME, Streeck H, Alter G. Fischinger S, et al. Among authors: vasan s. JCI Insight. 2020 Oct 8:140925. doi: 10.1172/jci.insight.140925. Online ahead of print. JCI Insight. 2020. PMID: 33031099 Free article.
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