Vasavada RC - Search Results

1

Novel proapoptotic effect of hepatocyte growth factor: synergy with palmitate to cause pancreatic {beta}-cell apoptosis.

González-Pertusa JA, Dubé J, Valle SR, Rosa TC, Takane KK, Mellado-Gil JM, Perdomo G, Vasavada RC, García-Ocaña A. González-Pertusa JA, et al. Among authors: vasavada rc. Endocrinology. 2010 Apr;151(4):1487-98. doi: 10.1210/en.2009-0975. Epub 2010 Feb 22. Endocrinology. 2010. PMID: 20176723 Free PMC article.

2

Overexpression of parathyroid hormone-related protein inhibits pancreatic beta-cell death in vivo and in vitro.

Cebrian A, García-Ocaña A, Takane KK, Sipula D, Stewart AF, Vasavada RC. Cebrian A, et al. Among authors: vasavada rc. Diabetes. 2002 Oct;51(10):3003-13. doi: 10.2337/diabetes.51.10.3003. Diabetes. 2002. PMID: 12351440

3

Adenovirus-mediated hepatocyte growth factor expression in mouse islets improves pancreatic islet transplant performance and reduces beta cell death.

Garcia-Ocana A, Takane KK, Reddy VT, Lopez-Talavera JC, Vasavada RC, Stewart AF. Garcia-Ocana A, et al. Among authors: vasavada rc. J Biol Chem. 2003 Jan 3;278(1):343-51. doi: 10.1074/jbc.M207848200. Epub 2002 Oct 25. J Biol Chem. 2003. PMID: 12403787 Free article.

4

Targeted inactivation of hepatocyte growth factor receptor c-met in beta-cells leads to defective insulin secretion and GLUT-2 downregulation without alteration of beta-cell mass.

Roccisana J, Reddy V, Vasavada RC, Gonzalez-Pertusa JA, Magnuson MA, Garcia-Ocaña A. Roccisana J, et al. Among authors: vasavada rc. Diabetes. 2005 Jul;54(7):2090-102. doi: 10.2337/diabetes.54.7.2090. Diabetes. 2005. PMID: 15983210

5

Growth factors and beta cell replication.

Vasavada RC, Gonzalez-Pertusa JA, Fujinaka Y, Fiaschi-Taesch N, Cozar-Castellano I, Garcia-Ocaña A. Vasavada RC, et al. Int J Biochem Cell Biol. 2006;38(5-6):931-50. doi: 10.1016/j.biocel.2005.08.003. Epub 2005 Aug 31. Int J Biochem Cell Biol. 2006. PMID: 16168703 Review.

6

Protein kinase C-zeta activation markedly enhances beta-cell proliferation: an essential role in growth factor mediated beta-cell mitogenesis.

Vasavada RC, Wang L, Fujinaka Y, Takane KK, Rosa TC, Mellado-Gil JM, Friedman PA, Garcia-Ocaña A. Vasavada RC, et al. Diabetes. 2007 Nov;56(11):2732-43. doi: 10.2337/db07-0461. Epub 2007 Aug 8. Diabetes. 2007. PMID: 17686945

7

Disruption of hepatocyte growth factor/c-Met signaling enhances pancreatic beta-cell death and accelerates the onset of diabetes.

Mellado-Gil J, Rosa TC, Demirci C, Gonzalez-Pertusa JA, Velazquez-Garcia S, Ernst S, Valle S, Vasavada RC, Stewart AF, Alonso LC, Garcia-Ocaña A. Mellado-Gil J, et al. Among authors: vasavada rc. Diabetes. 2011 Feb;60(2):525-36. doi: 10.2337/db09-1305. Epub 2010 Oct 27. Diabetes. 2011. PMID: 20980460 Free PMC article.

8

Activation of protein kinase C-ζ in pancreatic β-cells in vivo improves glucose tolerance and induces β-cell expansion via mTOR activation.

Velazquez-Garcia S, Valle S, Rosa TC, Takane KK, Demirci C, Alvarez-Perez JC, Mellado-Gil JM, Ernst S, Scott DK, Vasavada RC, Alonso LC, Garcia-Ocaña A. Velazquez-Garcia S, et al. Among authors: vasavada rc. Diabetes. 2011 Oct;60(10):2546-59. doi: 10.2337/db10-1783. Epub 2011 Sep 12. Diabetes. 2011. PMID: 21911744 Free PMC article.

9

Loss of HGF/c-Met signaling in pancreatic β-cells leads to incomplete maternal β-cell adaptation and gestational diabetes mellitus.

Demirci C, Ernst S, Alvarez-Perez JC, Rosa T, Valle S, Shridhar V, Casinelli GP, Alonso LC, Vasavada RC, García-Ocana A. Demirci C, et al. Among authors: vasavada rc. Diabetes. 2012 May;61(5):1143-52. doi: 10.2337/db11-1154. Epub 2012 Mar 16. Diabetes. 2012. PMID: 22427375 Free PMC article.

10

Hepatocyte growth factor ameliorates hyperglycemia and corrects β-cell mass in IRS2-deficient mice.

Alvarez-Perez JC, Rosa TC, Casinelli GP, Valle SR, Lakshmipathi J, Rosselot C, Rausell-Palamos F, Vasavada RC, García-Ocaña A. Alvarez-Perez JC, et al. Among authors: vasavada rc. Mol Endocrinol. 2014 Dec;28(12):2038-48. doi: 10.1210/me.2014-1207. Mol Endocrinol. 2014. PMID: 25361392 Free PMC article.

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