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Vascular endothelial growth factor (VEGF) - part 1: in physiology and pathophysiology.
Kajdaniuk D, Marek B, Borgiel-Marek H, Kos-Kudła B. Kajdaniuk D, et al. Endokrynol Pol. 2011;62(5):444-55. Endokrynol Pol. 2011. PMID: 22069106 Free article. Review.
Angiogenesis is an important component of many physiological processes, such as the female sexual cycle, placenta formation, the processes of growth and differentiation of tissues, and reparative processes including wound healing, fracture repair, and liver regenera …
Angiogenesis is an important component of many physiological processes, such as the female sexual cycle, placenta formation, the processes o …
Vascular inflammation and endothelial dysfunction in fracture healing.
Blum A, Zarqh O, Peleg A, Sirchan R, Blum N, Salameh Y, Ganaem M. Blum A, et al. Am J Orthop (Belle Mead NJ). 2012 Feb;41(2):87-91. Am J Orthop (Belle Mead NJ). 2012. PMID: 22482094
Angiogenesis is an important step in bone fracture healing. In this article, we report on the healing of long bone fractures, and the involvement of the vascular and the inflammatory systems in the process. ...In vivo measurements demonstrated severe …
Angiogenesis is an important step in bone fracture healing. In this article, we report on the healing of long bone frac …
Extracellular signaling molecules to promote fracture healing and bone regeneration.
Hankenson KD, Gagne K, Shaughnessy M. Hankenson KD, et al. Adv Drug Deliv Rev. 2015 Nov 1;94:3-12. doi: 10.1016/j.addr.2015.09.008. Epub 2015 Sep 30. Adv Drug Deliv Rev. 2015. PMID: 26428617 Review.
Vascular Endothelial Growth Factor (VEGF) likely has a special role. Not only does it induce new blood vessel formation, it also has direct effects on osteoblasts through endothelial cell-based BMP production. In addition to these pathways that classic
Vascular Endothelial Growth Factor (VEGF) likely has a special role. Not only does it induce new blood vessel formation
TNFalpha contributes to diabetes impaired angiogenesis in fracture healing.
Lim JC, Ko KI, Mattos M, Fang M, Zhang C, Feinberg D, Sindi H, Li S, Alblowi J, Kayal RA, Einhorn TA, Gerstenfeld LC, Graves DT. Lim JC, et al. Bone. 2017 Jun;99:26-38. doi: 10.1016/j.bone.2017.02.014. Epub 2017 Mar 8. Bone. 2017. PMID: 28285015 Free PMC article.
Diabetes increases the likelihood of fracture, interferes with fracture healing and impairs angiogenesis. The latter may be significant due to the critical nature of angiogenesis in fracture healing. Although it is known that diabetes interferes …
Diabetes increases the likelihood of fracture, interferes with fracture healing and impairs angiogenesis. The latter ma …
Localization of VEGF, TGF-β1, BMP-2, and Apoptosis Factors in Hypertrophic Nonunion of Human Tubular Bones.
Kostiv RE, Matveeva NY, Kalinichenko SG. Kostiv RE, et al. Bull Exp Biol Med. 2022 May;173(1):160-168. doi: 10.1007/s10517-022-05513-3. Epub 2022 May 28. Bull Exp Biol Med. 2022. PMID: 35624354
The number of immunopositive cells expressing TGF-beta1 and TNFalpha in the callus exceeded that in the control and correlated with the expression of caspase-3 in fibroblast-like cells, osteoblasts, chondroblasts, and microvascular endotheliocytes. The results allow considering …
The number of immunopositive cells expressing TGF-beta1 and TNFalpha in the callus exceeded that in the control and correlated with the expr …
Temporal profile of microvascular disturbances in rat tibial periosteum following closed soft tissue trauma.
Schaser KD, Zhang L, Haas NP, Mittlmeier T, Duda G, Bail HJ. Schaser KD, et al. Langenbecks Arch Surg. 2003 Oct;388(5):323-30. doi: 10.1007/s00423-003-0411-5. Epub 2003 Oct 8. Langenbecks Arch Surg. 2003. PMID: 14534794
BACKGROUND AND AIMS: Bone devascularization due to impaired periosteal perfusion following fracture with severe soft tissue trauma has been proposed to precede and underlie perturbed bone healing. ...Microcirculation of tibial periosteum in control rats demonstrated …
BACKGROUND AND AIMS: Bone devascularization due to impaired periosteal perfusion following fracture with severe soft tissue trauma ha …