Vasudevan SG - Search Results

1

Towards the design of antiviral inhibitors against flaviviruses: the case for the multifunctional NS3 protein from Dengue virus as a target.

Lescar J, Luo D, Xu T, Sampath A, Lim SP, Canard B, Vasudevan SG. Lescar J, et al. Among authors: vasudevan sg. Antiviral Res. 2008 Nov;80(2):94-101. doi: 10.1016/j.antiviral.2008.07.001. Epub 2008 Jul 30. Antiviral Res. 2008. PMID: 18674567 Review.

2

Functional profiling of recombinant NS3 proteases from all four serotypes of dengue virus using tetrapeptide and octapeptide substrate libraries.

Li J, Lim SP, Beer D, Patel V, Wen D, Tumanut C, Tully DC, Williams JA, Jiricek J, Priestle JP, Harris JL, Vasudevan SG. Li J, et al. Among authors: vasudevan sg. J Biol Chem. 2005 Aug 5;280(31):28766-74. doi: 10.1074/jbc.M500588200. Epub 2005 Jun 1. J Biol Chem. 2005. PMID: 15932883 Free article.

3

Structure of the Dengue virus helicase/nucleoside triphosphatase catalytic domain at a resolution of 2.4 A.

Xu T, Sampath A, Chao A, Wen D, Nanao M, Chene P, Vasudevan SG, Lescar J. Xu T, et al. Among authors: vasudevan sg. J Virol. 2005 Aug;79(16):10278-88. doi: 10.1128/JVI.79.16.10278-10288.2005. J Virol. 2005. PMID: 16051821 Free PMC article.

4

Peptide inhibitors of Dengue virus NS3 protease. Part 1: Warhead.

Yin Z, Patel SJ, Wang WL, Wang G, Chan WL, Rao KR, Alam J, Jeyaraj DA, Ngew X, Patel V, Beer D, Lim SP, Vasudevan SG, Keller TH. Yin Z, et al. Among authors: vasudevan sg. Bioorg Med Chem Lett. 2006 Jan 1;16(1):36-9. doi: 10.1016/j.bmcl.2005.09.062. Epub 2005 Oct 21. Bioorg Med Chem Lett. 2006. PMID: 16246553

5

Peptide inhibitors of dengue virus NS3 protease. Part 2: SAR study of tetrapeptide aldehyde inhibitors.

Yin Z, Patel SJ, Wang WL, Chan WL, Ranga Rao KR, Wang G, Ngew X, Patel V, Beer D, Knox JE, Ma NL, Ehrhardt C, Lim SP, Vasudevan SG, Keller TH. Yin Z, et al. Among authors: vasudevan sg. Bioorg Med Chem Lett. 2006 Jan 1;16(1):40-3. doi: 10.1016/j.bmcl.2005.09.049. Epub 2005 Oct 21. Bioorg Med Chem Lett. 2006. PMID: 16246563

6

Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus.

Erbel P, Schiering N, D'Arcy A, Renatus M, Kroemer M, Lim SP, Yin Z, Keller TH, Vasudevan SG, Hommel U. Erbel P, et al. Among authors: vasudevan sg. Nat Struct Mol Biol. 2006 Apr;13(4):372-3. doi: 10.1038/nsmb1073. Epub 2006 Mar 12. Nat Struct Mol Biol. 2006. PMID: 16532006

7

Structure-based mutational analysis of the NS3 helicase from dengue virus.

Sampath A, Xu T, Chao A, Luo D, Lescar J, Vasudevan SG. Sampath A, et al. Among authors: vasudevan sg. J Virol. 2006 Jul;80(13):6686-90. doi: 10.1128/JVI.02215-05. J Virol. 2006. PMID: 16775356 Free PMC article.

8

Dengue virus NS4B interacts with NS3 and dissociates it from single-stranded RNA.

Umareddy I, Chao A, Sampath A, Gu F, Vasudevan SG. Umareddy I, et al. Among authors: vasudevan sg. J Gen Virol. 2006 Sep;87(Pt 9):2605-2614. doi: 10.1099/vir.0.81844-0. J Gen Virol. 2006. PMID: 16894199

9

Peptide inhibitors of West Nile NS3 protease: SAR study of tetrapeptide aldehyde inhibitors.

Knox JE, Ma NL, Yin Z, Patel SJ, Wang WL, Chan WL, Ranga Rao KR, Wang G, Ngew X, Patel V, Beer D, Lim SP, Vasudevan SG, Keller TH. Knox JE, et al. Among authors: vasudevan sg. J Med Chem. 2006 Nov 2;49(22):6585-90. doi: 10.1021/jm0607606. J Med Chem. 2006. PMID: 17064076

10

A multi-step strategy to obtain crystals of the dengue virus RNA-dependent RNA polymerase that diffract to high resolution.

Yap TL, Chen YL, Xu T, Wen D, Vasudevan SG, Lescar J. Yap TL, et al. Among authors: vasudevan sg. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Feb 1;63(Pt 2):78-83. doi: 10.1107/S1744309106055084. Epub 2007 Jan 17. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007. PMID: 17277444 Free PMC article.

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