Vecellio ML - Search Results

1

Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy.

Picaud S, Fedorov O, Thanasopoulou A, Leonards K, Jones K, Meier J, Olzscha H, Monteiro O, Martin S, Philpott M, Tumber A, Filippakopoulos P, Yapp C, Wells C, Che KH, Bannister A, Robson S, Kumar U, Parr N, Lee K, Lugo D, Jeffrey P, Taylor S, Vecellio ML, Bountra C, Brennan PE, O'Mahony A, Velichko S, Müller S, Hay D, Daniels DL, Urh M, La Thangue NB, Kouzarides T, Prinjha R, Schwaller J, Knapp S. Picaud S, et al. Among authors: vecellio ml. Cancer Res. 2015 Dec 1;75(23):5106-5119. doi: 10.1158/0008-5472.CAN-15-0236. Epub 2015 Nov 9. Cancer Res. 2015. PMID: 26552700 Free PMC article.

2

CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses.

Hammitzsch A, Tallant C, Fedorov O, O'Mahony A, Brennan PE, Hay DA, Martinez FO, Al-Mossawi MH, de Wit J, Vecellio M, Wells C, Wordsworth P, Müller S, Knapp S, Bowness P. Hammitzsch A, et al. Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):10768-73. doi: 10.1073/pnas.1501956112. Epub 2015 Aug 10. Proc Natl Acad Sci U S A. 2015. PMID: 26261308 Free PMC article.

3

The histone acetylase activator pentadecylidenemalonate 1b rescues proliferation and differentiation in the human cardiac mesenchymal cells of type 2 diabetic patients.

Vecellio M, Spallotta F, Nanni S, Colussi C, Cencioni C, Derlet A, Bassetti B, Tilenni M, Carena MC, Farsetti A, Sbardella G, Castellano S, Mai A, Martelli F, Pompilio G, Capogrossi MC, Rossini A, Dimmeler S, Zeiher A, Gaetano C. Vecellio M, et al. Diabetes. 2014 Jun;63(6):2132-47. doi: 10.2337/db13-0731. Epub 2014 Jan 23. Diabetes. 2014. PMID: 24458358

4

ERAP1 association with ankylosing spondylitis is attributable to common genotypes rather than rare haplotype combinations.

Roberts AR, Appleton LH, Cortes A, Vecellio M, Lau J, Watts L, Brown MA, Wordsworth P. Roberts AR, et al. Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):558-561. doi: 10.1073/pnas.1618856114. Epub 2017 Jan 3. Proc Natl Acad Sci U S A. 2017. PMID: 28049827 Free PMC article.

5

RUNX3 and T-Bet in Immunopathogenesis of Ankylosing Spondylitis-Novel Targets for Therapy?

Vecellio M, Cohen CJ, Roberts AR, Wordsworth PB, Kenna TJ. Vecellio M, et al. Front Immunol. 2019 Jan 10;9:3132. doi: 10.3389/fimmu.2018.03132. eCollection 2018. Front Immunol. 2019. PMID: 30687330 Free PMC article. Review.

6

The genetic association of RUNX3 with ankylosing spondylitis can be explained by allele-specific effects on IRF4 recruitment that alter gene expression.

Vecellio M, Roberts AR, Cohen CJ, Cortes A, Knight JC, Bowness P, Wordsworth BP. Vecellio M, et al. Ann Rheum Dis. 2016 Aug;75(8):1534-40. doi: 10.1136/annrheumdis-2015-207490. Epub 2015 Oct 9. Ann Rheum Dis. 2016. PMID: 26452539 Free PMC article.

7

MicroRNAs in Axial Spondylarthritis: an Overview of the Recent Progresses in the Field with a Focus on Ankylosing Spondylitis and Psoriatic Arthritis.

Motta F, Pederzani A, Carena MC, Ceribelli A, Wordsworth PB, De Santis M, Selmi C, Vecellio M. Motta F, et al. Curr Rheumatol Rep. 2021 Jul 3;23(8):59. doi: 10.1007/s11926-021-01027-5. Curr Rheumatol Rep. 2021. PMID: 34216293 Free PMC article. Review.

8

An ankylosing spondylitis-associated genetic variant in the IL23R-IL12RB2 intergenic region modulates enhancer activity and is associated with increased Th1-cell differentiation.

Roberts AR, Vecellio M, Chen L, Ridley A, Cortes A, Knight JC, Bowness P, Cohen CJ, Wordsworth BP. Roberts AR, et al. Ann Rheum Dis. 2016 Dec;75(12):2150-2156. doi: 10.1136/annrheumdis-2015-208640. Epub 2016 Feb 25. Ann Rheum Dis. 2016. PMID: 26916345 Free PMC article.

9

Disruption of c-MYC Binding and Chromosomal Looping Involving Genetic Variants Associated With Ankylosing Spondylitis Upstream of the RUNX3 Promoter.

Cohen CJ, Davidson C, Selmi C, Bowness P, Knight JC, Wordsworth BP, Vecellio M. Cohen CJ, et al. Front Genet. 2022 Jan 7;12:741867. doi: 10.3389/fgene.2021.741867. eCollection 2021. Front Genet. 2022. PMID: 35069677 Free PMC article.

10

Evidence for a second ankylosing spondylitis-associated RUNX3 regulatory polymorphism.

Vecellio M, Cortes A, Roberts AR, Ellis J, Cohen CJ, Knight JC, Brown MA, Bowness P, Wordsworth BP. Vecellio M, et al. RMD Open. 2018 Feb 8;4(1):e000628. doi: 10.1136/rmdopen-2017-000628. eCollection 2018. RMD Open. 2018. PMID: 29531791 Free PMC article.

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