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Huperzine A, a potential therapeutic agent for dementia, reduces neuronal cell death caused by glutamate.
Ved HS, Koenig ML, Dave JR, Doctor BP. Ved HS, et al. Neuroreport. 1997 Mar 3;8(4):963-8. doi: 10.1097/00001756-199703030-00029. Neuroreport. 1997. PMID: 9141073
Identification and characterization of the major huperzine a metabolite in rat blood.
Garcia GE, Hicks RP, Skanchy D, Moorad-Doctor DR, Doctor BP, Ved HS. Garcia GE, et al. Among authors: ved hs. J Anal Toxicol. 2004 Jul-Aug;28(5):379-83. doi: 10.1093/jat/28.5.379. J Anal Toxicol. 2004. PMID: 15239859
The NMDA receptor ion channel: a site for binding of Huperzine A.
Gordon RK, Nigam SV, Weitz JA, Dave JR, Doctor BP, Ved HS. Gordon RK, et al. Among authors: ved hs. J Appl Toxicol. 2001 Dec;21 Suppl 1:S47-51. doi: 10.1002/jat.805. J Appl Toxicol. 2001. PMID: 11920920
Synthesis, chiral chromatographic separation, and biological activities of the enantiomers of 10,10-dimethylhuperzine A.
Rajendran V, Prakash KR, Ved HS, Saxena A, Doctor BP, Kozikowski AP. Rajendran V, et al. Among authors: ved hs. Bioorg Med Chem Lett. 2000 Nov 6;10(21):2467-9. doi: 10.1016/s0960-894x(00)00494-7. Bioorg Med Chem Lett. 2000. PMID: 11078202
Neuroprotective role of c-fos antisense oligonucleotide: in vitro and in vivo studies.
Lu XC, Tortella FC, Ved HS, Garcia GE, Dave JR. Lu XC, et al. Among authors: ved hs. Neuroreport. 1997 Sep 8;8(13):2925-9. doi: 10.1097/00001756-199709080-00024. Neuroreport. 1997. PMID: 9376532
Dodecylglycerol provides partial protection against glutamate toxicity in neuronal cultures derived from different regions of embryonic rat brain.
Dave JR, Koenig ML, Tortella FC, Pieringer RA, Doctor BP, Ved HS. Dave JR, et al. Among authors: ved hs. Mol Chem Neuropathol. 1997 Jan-Feb;30(1-2):1-13. doi: 10.1007/BF02815146. Mol Chem Neuropathol. 1997. PMID: 9138422
RS-100642-198, a novel sodium channel blocker, provides differential neuroprotection against hypoxia/hypoglycemia, veratridine or glutamate-mediated neurotoxicity in primary cultures of rat cerebellar neurons.
Dave JR, Lin Y, Ved HS, Koenig ML, Clapp L, Hunter J, Tortella FC. Dave JR, et al. Among authors: ved hs. Neurotox Res. 2001 Aug;3(4):381-95. doi: 10.1007/BF03033199. Neurotox Res. 2001. PMID: 14715468
Neuroprotection produced by the NAALADase inhibitor 2-PMPA in rat cerebellar neurons.
Tortella FC, Lin Y, Ved H, Slusher BS, Dave JR. Tortella FC, et al. Eur J Pharmacol. 2000 Aug 18;402(1-2):31-7. doi: 10.1016/s0014-2999(00)00519-7. Eur J Pharmacol. 2000. PMID: 10940354
Regulation of neuronal differentiation in neuron-enriched primary cultures from embryonic rat cerebra by platelet activating factor and the structurally related glycerol ether lipid, dodecylglycerol.
Ved HS, Gustow E, Pieringer RA. Ved HS, et al. J Neurosci Res. 1991 Oct;30(2):353-8. doi: 10.1002/jnr.490300211. J Neurosci Res. 1991. PMID: 1798056
Effect of hydrocortisone on myelin basic protein in developing primary brain cultures.
Ved HS, Gustow E, Pieringer RA. Ved HS, et al. Neurosci Lett. 1989 Apr 24;99(1-2):203-7. doi: 10.1016/0304-3940(89)90290-5. Neurosci Lett. 1989. PMID: 2473427
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