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Are substitutions in the first hypervariable region of the mitochondrial DNA displacement-loop in sudden infant death syndrome due to maternal inheritance?
Arnestad M, Opdal SH, Musse MA, Vege A, Rognum TO. Arnestad M, et al. Among authors: vege a. Acta Paediatr. 2002;91(10):1060-4. doi: 10.1080/080352502760311557. Acta Paediatr. 2002. PMID: 12434891
DISCUSSION: In patients with known mitochondrial (mt) DNA disease, a large number of sequence variants have been found in the D-loop region. Substitutions in the D-loop may be part of a haplotype with mutations elsewhere in the mtDNA. CONCLUSION: HVR1 substitutions …
DISCUSSION: In patients with known mitochondrial (mt) DNA disease, a large number of sequence variants have been found in the D-loop …
Changes in the concentration and distribution of immunoglobulin-producing cells in SIDS palatine tonsils.
Stoltenberg L, Vege A, Saugstad OD, Rognum TO. Stoltenberg L, et al. Among authors: vege a. Pediatr Allergy Immunol. 1995 Feb;6(1):48-55. doi: 10.1111/j.1399-3038.1995.tb00258.x. Pediatr Allergy Immunol. 1995. PMID: 7550766
SIDS cases have increased levels of interleukin-6 in cerebrospinal fluid.
Vege A, Rognum TO, Scott H, Aasen AO, Saugstad OD. Vege A, et al. Acta Paediatr. 1995 Feb;84(2):193-6. doi: 10.1111/j.1651-2227.1995.tb13608.x. Acta Paediatr. 1995. PMID: 7756807
Since IL-6 plays an important role in immune responses and may induce fever, the findings may suggest that immune activation plays a role in SIDS. ...
Since IL-6 plays an important role in immune responses and may induce fever, the findings may suggest that immune activation plays a
Vitreous humor hypoxanthine levels in SIDS and infectious death.
Vege A, Chen Y, Opdal SH, Saugstad OD, Rognum TO. Vege A, et al. Acta Paediatr. 1994 Jun;83(6):634-9. doi: 10.1111/j.1651-2227.1994.tb13096.x. Acta Paediatr. 1994. PMID: 7919762

The hypoxanthine measurements were made using a high-performance liquid chromatography method. The hypoxanthine levels were significantly (p < 0.01) higher in SIDS than in violent deaths, while no significant difference was found between SIDS and infectious deaths. The

The hypoxanthine measurements were made using a high-performance liquid chromatography method. The hypoxanthine levels were significa …
Is partial deletion of the complement C4 genes associated with sudden infant death?
Opdal SH, Vege A, Saugstad OD, Rognum TO. Opdal SH, et al. Among authors: vege a. Eur J Pediatr. 1994 Apr;153(4):287-90. doi: 10.1007/BF01954522. Eur J Pediatr. 1994. PMID: 8194566
This observation may indicate that a proportion of SID victims are more vulnerable to infections than other infants....
This observation may indicate that a proportion of SID victims are more vulnerable to infections than other infants....
Use of new Nordic criteria for classification of SIDS to re-evaluate diagnoses of sudden unexpected infant death in the Nordic countries.
Vege A, Rognum TO. Vege A, et al. Acta Paediatr. 1997 Apr;86(4):391-6. doi: 10.1111/j.1651-2227.1997.tb09029.x. Acta Paediatr. 1997. PMID: 9174226
To investigate whether changes in diagnostic practice might be the cause of the SIDS epidemic in the Nordic countries in the 1970s and 1980s a cooperative study was initiated in 1990. ...
To investigate whether changes in diagnostic practice might be the cause of the SIDS epidemic in the Nordic countries in the 1970s and 1980s …
Hypoxanthine levels in vitreous humor: a study of influencing factors in sudden infant death syndrome.
Opdal SH, Rognum TO, Vege A, Saugstad OD. Opdal SH, et al. Among authors: vege a. Pediatr Res. 1998 Aug;44(2):192-6. doi: 10.1203/00006450-199808000-00009. Pediatr Res. 1998. PMID: 9702913
Thirteen cases of violent death, 11 cases of borderline SIDS, 22 cases of death from infectious disease, and 17 cases of death from heart/lung disease were compared with a 3-fold number of SIDS cases. ...
Thirteen cases of violent death, 11 cases of borderline SIDS, 22 cases of death from infectious disease, and 17 cases of death from heart/lu …
SIDS--changes in the epidemiological pattern in eastern Norway 1984-1996.
Vege A, Rognum TO, Opdal SH. Vege A, et al. Forensic Sci Int. 1998 May 11;93(2-3):155-66. doi: 10.1016/s0379-0738(98)00048-6. Forensic Sci Int. 1998. PMID: 9717266
Are elevated cerebrospinal fluid levels of IL-6 in sudden unexplained deaths, infectious deaths and deaths due to heart/lung disease in infants and children due to hypoxia?
Vege A, Rognum TO, Aasen AO, Saugstad OD. Vege A, et al. Acta Paediatr. 1998 Aug;87(8):819-24. doi: 10.1080/080352598750013563. Acta Paediatr. 1998. PMID: 9736227
In the cases studied IL-6 elevation is probably not induced by hypoxia, but is rather a result of immunological stimulation....
In the cases studied IL-6 elevation is probably not induced by hypoxia, but is rather a result of immunological stimulation....
Increased number of substitutions in the D-loop of mitochondrial DNA in the sudden infant death syndrome.
Opdal SH, Rognum TO, Vege A, Stave AK, Dupuy BM, Egeland T. Opdal SH, et al. Among authors: vege a. Acta Paediatr. 1998 Oct;87(10):1039-44. doi: 10.1080/080352598750031347. Acta Paediatr. 1998. PMID: 9825969
These include elevated levels of vitreous humour hypoxanthine in SIDS victims, familial clustering without mendelian traits, and observations of increased sleepiness and a lower activity score in infants who later succumbed to SIDS. ...The SIDS cases had a tendency …
These include elevated levels of vitreous humour hypoxanthine in SIDS victims, familial clustering without mendelian traits, and observation …
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